NJUCal‐1: A New Calcite Oxygen Isotope Reference Material for Microbeam Analysis

2021 ◽  
Author(s):  
Rucao Li ◽  
Xiao‐Lei Wang ◽  
Huayong Chen ◽  
Hui Zheng ◽  
Yue Guan ◽  
...  
Keyword(s):  
Reference Material ◽  
Oxygen Isotope ◽  
Microbeam Analysis

Revisiting apatite SIMS oxygen isotope analysis and qinghu reference material

2021 ◽  
pp. 120445
Author(s):  
Yang Li ◽  
Guo-Qiang Tang ◽  
Yu Liu ◽  
Sheng He ◽  
Bo Chen ◽  
...  
Keyword(s):  
Reference Material ◽  
Oxygen Isotope ◽  
Isotope Analysis

A new isotopic reference material for stable hydrogen and oxygen isotope-ratio measurements of water - USGS50 Lake Kyoga Water

2015 ◽  
Vol 29 (21) ◽  
pp. 2078-2082 ◽  
Author(s):  
Tyler B. Coplen ◽  
Leonard I. Wassenaar ◽  
Christine Mukwaya ◽  
Haiping Qi ◽  
Jennifer M. Lorenz
Keyword(s):  
Reference Material ◽  
Oxygen Isotope ◽  
Isotope Ratio ◽  
Oxygen Isotope Ratio ◽  
Hydrogen And Oxygen Isotope ◽  
Isotope Ratio Measurements

A novel micro-structured reference material for microbeam analysis

2000 ◽  
Vol 161-163 ◽  
pp. 359-365 ◽  
Author(s):  
Uwe Wätjen ◽  
Csaba Dücsö ◽  
Antonella Tajani ◽  
Frans Munnik ◽  
Frank Lechtenberg
Keyword(s):  
Reference Material ◽  
Microbeam Analysis

A Novel Micro-Structured Reference Material for Ion and X-Ray Microbeam Analysis

2000 ◽  
Vol 132 (2-4) ◽  
pp. 521-525
Author(s):  
Uwe Wätjen ◽  
István Bársony ◽  
Csaba Dücsö
Keyword(s):  
Reference Material ◽  
X Ray ◽  
Microbeam Analysis

Lateral resolution of the electron microbeam analysis

1978 ◽  
Vol 36 (1) ◽  
pp. 542-543
Author(s):  
H.J. Dudek
Keyword(s):  
Quantitative Analysis ◽  
Depth Resolution ◽  
Lateral Resolution ◽  
Cylindrical Particle ◽  
Correction Procedure ◽  
X Ray ◽  
Element Concentrations ◽  
Microbeam Analysis ◽  
The Matrix

The chemical inhomogenities in modern materials such as fibers, phases and inclusions, often have diameters in the region of one micrometer. Using electron microbeam analysis for the determination of the element concentrations one has to know the smallest possible diameter of such regions for a given accuracy of the quantitative analysis.In th is paper the correction procedure for the quantitative electron microbeam analysis is extended to a spacial problem to determine the smallest possible measurements of a cylindrical particle P of high D (depth resolution) and diameter L (lateral resolution) embeded in a matrix M and which has to be analysed quantitative with the accuracy q. The mathematical accounts lead to the following form of the characteristic x-ray intens ity of the element i of a particle P embeded in the matrix M in relation to the intensity of a standard S

Landscape development in response to climatic change during Oxygen Isotope Stage 5 in the southern Siberian loess region

Boreas ◽  
2004 ◽  
Vol 33 (2) ◽  
pp. 164-180 ◽  
Author(s):  
Jiri Chlachula ◽  
Rob Kemp ◽  
Catherine Jessen ◽  
Adrian Palmer ◽  
Phillip Toms
Keyword(s):  
Oxygen Isotope ◽  
Climatic Change ◽  
Landscape Development ◽  
Oxygen Isotope Stage ◽  
Loess Region

Multi-Center Calibration of the Second Reference Material for Thromboplastin, Rabbit, Plain, Coded CRM 149R

1991 ◽  
Vol 65 (03) ◽  
pp. 263-267 ◽  
Author(s):  
A M H P van den Besselaar ◽  
R M Bertina
Keyword(s):  
Reference Material ◽  
Standard Error ◽  
Standard Errors ◽  
Sensitivity Index ◽  
Long Term Stability ◽  
Significant Bias ◽  
The Mean ◽  
The Relationship ◽  
International Sensitivity Index

SummaryIn a collaborative trial of eleven laboratories which was performed mainly within the framework of the European Community Bureau of Reference (BCR), a second reference material for thromboplastin, rabbit, plain, was calibrated against its predecessor RBT/79. This second reference material (coded CRM 149R) has a mean International Sensitivity Index (ISI) of 1.343 with a standard error of the mean of 0.035. The standard error of the ISI was determined by combination of the standard errors of the ISI of RBT/79 and the slope of the calibration line in this trial.The BCR reference material for thromboplastin, human, plain (coded BCT/099) was also included in this trial for assessment of the long-term stability of the relationship with RBT/79. The results indicated that this relationship has not changed over a period of 8 years. The interlaboratory variation of the slope of the relationship between CRM 149R and RBT/79 was significantly lower than the variation of the slope of the relationship between BCT/099 and RBT/79. In addition to the manual technique, a semi-automatic coagulometer according to Schnitger & Gross was used to determine prothrombin times with CRM 149R. The mean ISI of CRM 149R was not affected by replacement of the manual technique by this particular coagulometer.Two lyophilized plasmas were included in this trial. The mean slope of relationship between RBT/79 and CRM 149R based on the two lyophilized plasmas was the same as the corresponding slope based on fresh plasmas. Tlowever, the mean slope of relationship between RBT/79 and BCT/099 based on the two lyophilized plasmas was 4.9% higher than the mean slope based on fresh plasmas. Thus, the use of these lyophilized plasmas induced a small but significant bias in the slope of relationship between these thromboplastins of different species.

Effect of Concentration of Trisodium Citrate Anticoagulant on Calculation of the International Normalised Ratio and the International Sensitivity Index of Thromboplastin

1994 ◽  
Vol 72 (01) ◽  
pp. 084-088 ◽  
Author(s):  
E M Duncan ◽  
C R Casey ◽  
B M Duncan ◽  
J V Lloyd
Keyword(s):  
Reference Material ◽  
Oral Anticoagulants ◽  
Reference Method ◽  
Trisodium Citrate ◽  
Sensitivity Index ◽  
Blood Samples ◽  
Orthogonal Regression ◽  
Significant Difference ◽  
International Normalised Ratio ◽  
International Sensitivity Index

SummaryThe aim of this study was to determine whether the concentration of trisodium citrate used to anticoagulate blood has an effect on the INR of the sample and the ISI of the thromboplastin. Five thromboplastins including and Australian reference material were used to measure the prothrombin time of normal and patient samples collected into two concentrations of trisodium citrate - 109 mM and 129 mM. There was no effect of citrate concentration on the INRs determined with the reference material. However for the other four thromboplastins there was a significant difference between INRs for the two citrate groups. The prothrombin times of the samples collected into 129 mM were longer than those collected into 109 mM. This difference was only slight in normal plasma but more marked in patients receiving oral anticoagulants, causing the INRs for patient plasmas collected into 129 mM citrate to be higher then the corresponding samples collected into 109 mM citrate.From orthogonal regression of log prothrombin times by the reference method against each thromboplastin, we found that the ISI for each thromboplastin was approximately 10% lower when determined with samples collected into 129 mM citrate than with samples collected into 109 mM. These results suggest that the concentration of trisodium citrate used for collection of blood samples can affect the calculation of the INR and the calibration of the ISI of thromboplastin. This was found both for commercial thromboplastins prepared by tissue extraction and for a recombinant tissue factor.

BIOASSAY CHARACTERISTICS OF INDIVIDUAL URINARY GONADOTROPHIN EXTRACTS

1963 ◽  
Vol 42 (2) ◽  
pp. 214-224
Author(s):  
Raymond C. Mellinger ◽  
Jalileh A. Mansour ◽  
Richmond W. Smith
Keyword(s):  
Reference Material ◽  
Young Women ◽  
Reference Standard ◽  
General Acceptance ◽  
Modifying Factors ◽  
Large Numbers ◽  
The World ◽  
Quantitative Bioassay ◽  
Different Parts ◽  
Age And Sex

ABSTRACT A reference standard is widely sought for use in the quantitative bioassay of pituitary gonadotrophin recovered from urine. The biologic similarity of pooled urinary extracts obtained from large numbers of subjects, utilizing groups of different age and sex, preparing and assaying the materials by varying techniques in different parts of the world, has lead to a general acceptance of such preparations as international gonadotrophin reference standards. In the present study, however, the extract of pooled urine from a small number of young women is shown to produce a significantly different bioassay response from that of the reference materials. Gonadotrophins of individual subjects likewise varied from the multiple subject standards in many instances. The cause of these differences is thought to be due to the modifying influence of non-hormonal substances extracted from urine with the gonadotrophin and not necessarily to variations in the gonadotrophins themselves. Such modifying factors might have similar effects in a comparative assay of pooled extracts contributed by many subjects, but produce significant variations when material from individual subjects is compared. It is concluded that the expression of potency of a gonadotrophic extract in terms of pooled reference material to which it is not essentially similar may diminish rather than enhance the validity of the assay.

Sign in / Sign up

Export Citation Format

Share Document