Dizziness in patients with early stages of Parkinson's disease: Prevalence, clinical characteristics and implications

2020 ◽  
Vol 20 (5) ◽  
pp. 443-447
Author(s):  
Kyum‐Yil Kwon ◽  
Suyeon Park ◽  
Mina Lee ◽  
Hyunjin Ju ◽  
Kayeong Im ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Characteristics ◽  
Disease Prevalence ◽  
Early Stages

scholarly journals Autonomic Dysfunctions in Parkinson’s Disease: Prevalence, Clinical Characteristics, Potential Diagnostic Markers, and Treatment

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Zhe Zhang ◽  
Sheng-Di Chen
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Characteristics ◽  
Treatment Options ◽  
Clinical Manifestations ◽  
The Elderly ◽  
Disease Prevalence ◽  
Autonomic Dysfunctions

Parkinson’s disease (PD) is a common neurodegenerative disease in the middle-aged and the elderly. Symptoms of autonomic dysfunctions are frequently seen in PD patients, severely affecting the quality of life. This review summarizes the epidemiology, clinical manifestations, and treatment options of autonomic dysfunctions. The clinical significance of autonomic dysfunctions in PD early diagnosis and differential diagnosis is also discussed.

scholarly journals Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson’s Disease and Idiopathic Anosmia

2021 ◽  
pp. 1-15
Author(s):  
Cristina Simonet ◽  
Miquel A. Galmes ◽  
Christian Lambert ◽  
Richard N. Rees ◽  
Tahrina Haque ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rating Scales ◽  
Early Stage ◽  
Slow Motion ◽  
Motor Dysfunction ◽  
Prodromal Phase ◽  
Floor Effect ◽  
Cross Sectional ◽  
Early Stages

Background: Bradykinesia is the defining motor feature of Parkinson’s disease (PD). There are limitations to its assessment using standard clinical rating scales, especially in the early stages of PD when a floor effect may be observed. Objective: To develop a quantitative method to track repetitive tapping movements and to compare people in the early stages of PD, healthy controls, and individuals with idiopathic anosmia. Methods: This was a cross-sectional study of 99 participants (early-stage PD = 26, controls = 64, idiopathic anosmia = 9). For each participant, repetitive finger tapping was recorded over 20 seconds using a smartphone at 240 frames per second. From each video, amplitude between fingers, frequency (number of taps per second), and velocity (distance travelled per second) was extracted. Clinical assessment was based on the motor section of the MDS-UPDRS. Results: People in the early stage of PD performed the task with slower velocity (p <  0.001) and with greater frequency slope than controls (p = 0.003). The combination of reduced velocity and greater frequency slope obtained the best accuracy to separate early-stage PD from controls based on metric thresholds alone (AUC = 0.88). Individuals with anosmia exhibited slower velocity (p = 0.001) and smaller amplitude (p <  0.001) compared with controls. Conclusion: We present a simple, proof-of-concept method to detect early motor dysfunction in PD. Mean tap velocity appeared to be the best parameter to differentiate patients with PD from controls. Patients with anosmia also showed detectable differences in motor performance compared with controls which may suggest that some are in the prodromal phase of PD.

Clinical characteristics of Parkinson's disease in Sudanese patients attending Daoud Charity Clinic in 2020–2021

2021 ◽  
Vol 429 ◽  
pp. 119594
Author(s):  
Radi Tofaha Alhusseini ◽  
Abbasher Hussien ◽  
Khabab Mohamed Ahmed ◽  
Hussien Abbashar ◽  
Amira Abdelgalil ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Characteristics

scholarly journals The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson’s Disease

2019 ◽  
Vol 9 (3) ◽  
pp. 553-563 ◽  
Author(s):  
Diane Stephenson ◽  
Derek Hill ◽  
Jesse M. Cedarbaum ◽  
Maria Tome ◽  
Spiros Vamvakas ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Trials ◽  
Early Stages

Camptocormia in Idiopathic Parkinson’s Disease: [123I]β-CIT SPECT and Clinical Characteristics

2003 ◽  
Vol 50 (2) ◽  
pp. 118-120 ◽  
Author(s):  
Iris Holler ◽  
Georg Dirnberger ◽  
Walter Pirker ◽  
Eduard Auff ◽  
Willibald Gerschlager
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Characteristics ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease
Sign in / Sign up

Export Citation Format

Share Document