Pressure pain threshold is higher in hypertensive compared with normotensive older adults: A case-control study

2016 ◽  
Vol 17 (6) ◽  
pp. 967-972 ◽  
Author(s):  
Marcelo Nascimento Rebelatto ◽  
Francisco Alburquerque-Sendín ◽  
João Flavio Guimarães ◽  
Tania Fatima Salvini
Keyword(s):  
Older Adults ◽  
Pain Threshold ◽  
Case Control Study ◽  
Pressure Pain Threshold ◽  
Case Control ◽  
Pressure Pain ◽  
Control Study

scholarly journals Identification of the optimal points for the acupuncture treatment of neck pain in China: protocol for a multicenter, matched, case-control study

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e029194 ◽  
Author(s):  
Mingsheng Sun ◽  
Siyuan Tao ◽  
Guoyan Geng ◽  
Jieru Peng ◽  
Xingsha Ma ◽  
...  
Keyword(s):  
Neck Pain ◽  
Pain Threshold ◽  
Case Control Study ◽  
Skin Resistance ◽  
Pressure Pain Threshold ◽  
Case Control ◽  
Body Regions ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

IntroductionNeck pain (NP) is a common condition that can be effectively treated by acupuncture. However, several treatment point prescriptions (ie, local acupoints, distal acupoints, and sensitised acupoints) may be used. The present study aims to identify the types of sensitisation and the distribution of sensitised points in patients with NP, to analyse the cut-off values and sensitisation rate for acupoint sensitisation, and to summarise the dominant forms of optimally sensitised points. This information will be helpful when choosing the optimal points to treat NP.Methods and analysisThis multicentre, matched, case–control study will enrol 224 patients with NP, and 224 age-matched and sex-matched healthy participants as controls. Body surface temperature, mechanical pain threshold, pressure pain threshold and skin resistance will be assessed at the 15 acupoints most frequently used to treat NP, and at the five body regions in which pain occurs most frequently. Hypothesis testing will be used to compare the differences in variables between cases and controls. In addition, receiver operating characteristic curve analysis will be used to explore the cut-off values of the sensitive states of heat, pain and electrical resistance, which indicate sensitisation of the acupoint. The optimal points will be comprehensively determined by the acupoint sensitisation rate and OR.Ethics and disseminationEthical approval of this study has been granted by the Research Ethical Committee of the Teaching Hospital of Chengdu University of Traditional Chinese Medicine (ID: 2018 KL-016). The outcomes of the study will be disseminated through peer-reviewed publications.Trial registrationChiCTR1800016220.

scholarly journals Plasma acylcarnitines and risk of lower-extremity functional impairment in older adults: a nested case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Francisco Félix Caballero ◽  
Ellen A. Struijk ◽  
Alberto Lana ◽  
Antonio Buño ◽  
Fernando Rodríguez-Artalejo ◽  
...  
Keyword(s):  
Older Adults ◽  
Confidence Interval ◽  
Lower Extremity ◽  
Functional Impairment ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Community Dwelling ◽  
Control Study ◽  
Long Chain

AbstractElevated concentrations of acylcarnitines have been associated with higher risk of obesity, type 2 diabetes and cardiovascular disease. The aim of the present study was to assess the association between L-carnitine and acylcarnitine profiles, and 2-year risk of incident lower-extremity functional impairment (LEFI). This case–control study is nested in the Seniors-ENRICA cohort of community-dwelling older adults, which included 43 incident cases of LEFI and 86 age- and sex- matched controls. LEFI was assessed with the Short Physical Performance Battery. Plasma L-carnitine and 28 acylcarnitine species were measured. After adjusting for potential confounders, medium-chain acylcarnitines levels were associated with 2-year incidence of LEFI [odds ratio per 1-SD increase: 1.69; 95% confidence interval: 1.08, 2.64; p = 0.02]. Similar results were observed for long-chain acylcarnitines [odds ratio per 1-SD increase: 1.70; 95% confidence interval: 1.03, 2.80; p = 0.04]. Stratified analyses showed a stronger association between medium- and long-chain acylcarnitines and incidence of LEFI among those with body mass index and energy intake below the median value. In conclusion, higher plasma concentrations of medium- and long-chain acylcarnitines were associated with higher risk of LEFI. Given the role of these molecules on mitochondrial transport of fatty acids, our results suggest that bioenergetics dysbalance contributes to LEFI.

scholarly journals Association between anxiety symptoms and atrial fibrillation in a community cohort of Chinese older adults: a case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhu-Xia Shen ◽  
Yu-Min Sun ◽  
Hui-Hui Gu ◽  
Yan Zhang ◽  
Zhi-Wen Shen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Older Adults ◽  
Heart Disease ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Anxiety Symptoms ◽  
Control Group ◽  
Community Based ◽  
Control Study

Abstract Background The association between anxiety and atrial fibrillation (AF) remains unclear. Moreover, this association has rarely been studied in Chinese individuals aged 60 years or older. This study investigated the association between anxiety and AF in a community-based case-control study of older adult residents in urban China. Methods The cases and controls were from a community-based study conducted in the Jingansi community in Shanghai, China, between January 2010 and December 2012. A total of 3622 residents aged 60 years or older without severe vision, hearing, or speaking impairments were eligible to participate in the physical examinations and questionnaire survey. AF was assessed based on a previous physician’s diagnosis, electrocardiogram, ambulatory electrocardiogram, or echocardiogram. Anxiety was evaluated using the Zung Self-Rating Anxiety Scale (ZSAS). Using the AF group as a reference, the control group consisted of randomly selected age- and sex-matched individuals in a 1:5 ratio (case:control = 1:5). The association between anxiety and AF in the AF group and the multifactor-matched control group was explored using logistic regression. Results In the AF and control groups, after adjusting for a history of coronary heart disease, valvular heart disease, hypertension, stroke, hyperlipidemia, and diabetes, as well as depression score, ZSAS scores (odds ratio 1.07; 95% confidence interval 1.02–1.12; p = 0.003), and anxiety symptoms (odds ratio 3.94; 95% confidence interval 1.06–14.70; p = 0.041) were associated with AF. Conclusions Anxiety symptoms were associated with AF in a Chinese older population. This suggests that older adults who have anxiety symptoms may need psychological intervention or treatment in daily life and care.

Use of medications that antagonize mediators of inflammatory responses may reduce the risk of delirium in older adults: a nested case-control study

2016 ◽  
Vol 32 (2) ◽  
pp. 208-213 ◽  
Author(s):  
Martin G. Cole ◽  
Jane McCusker ◽  
Machelle Wilchesky ◽  
Philippe Voyer ◽  
Johanne Monette ◽  
...  
Keyword(s):  
Older Adults ◽  
Case Control Study ◽  
Inflammatory Responses ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

Changes in Health-Related Quality of Life Among Older Adults with Prostate Cancer: A Case-Control Study

2017 ◽  
Vol 225 (4) ◽  
pp. e105
Author(s):  
Gopal L. Narang ◽  
Angela B. Smith ◽  
Byron Jaeger ◽  
Laura Pinheiro ◽  
Lloyd J. Edwards ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Older Adults ◽  
Case Control Study ◽  
Case Control ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Control Study

scholarly journals Repeated influenza vaccination for preventing severe and fatal influenza infection in older adults: a multicentre case–control study

2018 ◽  
Vol 190 (1) ◽  
pp. E3-E12 ◽  
Author(s):  
Itziar Casado ◽  
Ángela Domínguez ◽  
Diana Toledo ◽  
Judith Chamorro ◽  
Jenaro Astray ◽  
...  
Keyword(s):  
Older Adults ◽  
Influenza Vaccination ◽  
Case Control Study ◽  
Influenza Infection ◽  
Case Control ◽  
Control Study
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