scholarly journals Left ventricular diastolic dysfunction is associated with cerebral white matter lesions (leukoaraiosis) in elderly patients without ischemic heart disease and stroke

2014 ◽  
Vol 14 ◽  
pp. 71-76 ◽  
Author(s):  
Atsuya Shimizu ◽  
Takashi Sakurai ◽  
Toko Mitsui ◽  
Motohiro Miyagi ◽  
Kenichiro Nomoto ◽  
...  
Keyword(s):  
Heart Disease ◽  
White Matter ◽  
Elderly Patients ◽  
Ischemic Heart Disease ◽  
White Matter Lesions ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Cerebral White Matter ◽  
Cerebral White Matter Lesions ◽  
Ventricular Diastolic Dysfunction

scholarly journals Connecting Cerebral White Matter Lesions and Hypertensive Target Organ Damage

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Cristina Sierra ◽  
Alfons López-Soto ◽  
Antonio Coca
Keyword(s):  
Risk Factor ◽  
White Matter ◽  
Brain Damage ◽  
White Matter Lesions ◽  
Organ Damage ◽  
Left Ventricular ◽  
Cerebral White Matter ◽  
Chronic Hypertension ◽  
Cerebral White Matter Lesions ◽  
The Brain

Chronic hypertension leads to concomitant remodeling of the cardiac and vascular systems and various organs, especially the brain, kidney, and retina. The brain is an early target of organ damage due to high blood pressure, which is the major modifiable risk factor for stroke and small vessel disease. Stroke is the second leading cause of death and the number one cause of disability worldwide and over 80% of strokes occur in the elderly. Preclinical hypertensive lesions in most target organs are clearly identified: left ventricular hypertrophy for the heart, microalbuminuria for the kidney, fundus abnormalities for the eye, and intima-media thickness and pulse wave velocity for the vessels. However, early hypertensive brain damage is not fully studied due to difficulties in access and the expense of techniques. After age, hypertension is the most-important risk factor for cerebral white matter lesions, which are an important prognostic factor for stroke, cognitive impairment, dementia, and death. Studies have shown an association between white matter lesions and a number of extracranial systems affected by high BP and also suggest that correct antihypertensive treatment could slow white matter lesions progression. There is strong evidence that cerebral white matter lesions in hypertensive patients should be considered a silent early marker of brain damage.

scholarly journals Left ventricular diastolic dysfunction in women with nonobstructive ischemic heart disease: insights from magnetic resonance imaging and spectroscopy

2017 ◽  
Vol 313 (4) ◽  
pp. R322-R329 ◽  
Author(s):  
Michael D. Nelson
Keyword(s):  
Heart Failure ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Obstructive Coronary Artery Disease ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Major Adverse Cardiovascular Events ◽  
Ventricular Diastolic Dysfunction

Ischemic heart disease, in the absence of obstructive coronary artery disease, is prevalent in women and constitutes a major risk factor for developing major adverse cardiovascular events, including myocardial infarction, stroke, and heart failure. For decades, diagnosis was considered benign and often minimized; however, it is now known that this etiology carries much risk and is a significant burden to the health care system. This review summarizes the current state of knowledge on nonobstructive ischemic heart disease (NOIHD), the association between NOIHD and left ventricular diastolic dysfunction, potential links between NOIHD and the development of heart failure with preserved ejection fraction (HFpEF), and therapeutic options and knowledge gaps for patients living with NOIHD.

scholarly journals Left ventricular diastolic dysfunction in primary hypertension and ischemic heart disease-evaluation by doppler echocardiography

2021 ◽  
Vol 8 (6) ◽  
pp. 770
Author(s):  
Rahul Kumar ◽  
Sanjeev Diwakar ◽  
Srinivas .
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diastolic Dysfunction ◽  
Diastolic Function ◽  
Doppler Echocardiography ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Filling Fraction ◽  
Ventricular Diastolic Dysfunction

Background: Congestive heart failure caused by a predominant abnormality in diastolic function is both common and causes significant morbidity and mortality. The objective of the study was to evaluate application of doppler echocardiography in determining left ventricular diastolic dysfunction in ischemic heart disease and essential hypertension.Methods: Present study is based on analysis of 75 patients of hypertension and 60 patients of IHD (UA, AMI, IMI) admitted to Bapuji and Chigateri general hospital during December 2019 to November 2020. Detailed history and physical examination were done. Every patient was subjected to ECG, CXR, routine investigations and Doppler Echo cardiography.Results: A total of 75 patients of primary hypertension were studied. 37 patients showed diastolic dysfunction with E/A ratio <1, with increased atrial filling fraction. Out of 37 patients, 24 showed LVH and 13 cases did not have LVH. A total of 60 patients of ischemic heart disease were studied. 23 patients showed diastolic dysfunction with E/A ratio <1, with increased atrial filling fraction and prolonged isovolumetric relaxation time.Conclusions: Our findings suggest that myocardial damage in patients with HTN and IHD affects diastolic dysfunction before systolic dysfunction. Doppler echocardiography is a valuable non-invasive method to detect left ventricular diastolic impairment and the intentional assessment of diastolic function is advisable for early detection of LV dysfunction before clinical symptoms appear.

Sign in / Sign up

Export Citation Format

Share Document