scholarly journals Motif‐driven protein binder design towards transferrin receptor helical domain

FEBS Journal ◽  
2021 ◽  
Author(s):  
Dick J Sjöström ◽  
Camilla Mohlin ◽  
Elena Ambrosetti ◽  
Scott J Garforth ◽  
Ana I Teixeira ◽  
...  
Keyword(s):  
Transferrin Receptor ◽  
Helical Domain

Structural Reorganization of the Transferrin C-Lobe and Transferrin Receptor upon Complex Formation:  The C-Lobe Binds to the Receptor Helical Domain†

Biochemistry ◽  
2003 ◽  
Vol 42 (43) ◽  
pp. 12447-12454 ◽  
Author(s):  
Rutao Liu ◽  
Jing-Qu Guan ◽  
Olga Zak ◽  
Philip Aisen ◽  
Mark R. Chance
Keyword(s):  
Complex Formation ◽  
Transferrin Receptor ◽  
Structural Reorganization ◽  
Helical Domain

scholarly journals Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis

mAbs ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 1874121
Author(s):  
Hsueh-Yuan Chang ◽  
Shengjia Wu ◽  
Yingyi Li ◽  
Wanying Zhang ◽  
Matthew Burrell ◽  
...  
Keyword(s):  
Transferrin Receptor ◽  
Antibody Affinity ◽  
Receptor Antibody

scholarly journals Effect of Fortification with Multiple Micronutrient Powder on the Prevention and Treatment of Iron Deficiency and Anaemia in Brazilian Children: A Randomized Clinical Trial

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2160
Author(s):  
Malaine Morais Alves Machado ◽  
Mirella de Paiva Lopes ◽  
Raquel Machado Schincaglia ◽  
Paulo Sérgio Sucasas da Costa ◽  
Alexandre Siqueira Guedes Coelho ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Transferrin Receptor ◽  
Ferrous Sulfate ◽  
Soluble Transferrin Receptor ◽  
Standard Drug ◽  
Micronutrient Powder ◽  
Prevention And Treatment ◽  
Multiple Micronutrient ◽  
Multiple Micronutrient Powder

Fortification with multiple micronutrient powder has been proposed as a public health intervention able to reduce micronutrient deficiencies in children. Our objective was to compare the effectiveness of fortification with multiple micronutrient powder with drug supplementation in the prevention and treatment of iron deficiency and anaemia. This was a cluster trial with anemic and non-anaemic children between six and 42 months old, in randomization data. Non anaemic children received fortification with multiple micronutrient powder or standard drug supplementation of ferrous sulfate associated with folic acid in a prevention dose. Anaemic children who were randomized to receive multiple micronutrient powder also received the recommended iron complementation for anaemia treatment. A total of 162 children were evaluated. The prevalence of anaemia decreased from 13.58 to 1.85%. Iron deficiency decreased from 21.74% to 7.89% (by serum ferritin) and iron deficiency decreased from 66.81 to 38.27% (by soluble transferrin receptor). No difference was identified between interventions for hemoglobin (p = 0.142), serum ferritin (p = 0.288), and soluble transferrin receptor (p = 0.156). Fortification with multiple micronutrient powder was effective in preventing iron deficiency and anaemia in children aged six to 48 months. In anaemic children; it was necessary to supplement the dose of multiple micronutrient powder with ferrous sulfate.

scholarly journals Roquin is a major mediator of iron-regulated changes to transferrin receptor-1 mRNA stability

iScience ◽  
2021 ◽  
Vol 24 (4) ◽  
pp. 102360
Author(s):  
Victor M. Corral ◽  
Eric R. Schultz ◽  
Richard S. Eisenstein ◽  
Gregory J. Connell
Keyword(s):  
Mrna Stability ◽  
Transferrin Receptor ◽  
Transferrin Receptor 1 ◽  
Major Mediator
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