scholarly journals Real-time analysis of conformational control in electron transfer reactions of human cytochrome P450 reductase with cytochromec

FEBS Journal ◽  
2015 ◽  
Vol 282 (22) ◽  
pp. 4357-4375 ◽  
Author(s):  
Tobias M. Hedison ◽  
Sam Hay ◽  
Nigel S. Scrutton
Keyword(s):  
Electron Transfer ◽  
Cytochrome P450 ◽  
Real Time ◽  
Transfer Reactions ◽  
Cytochrome P450 Reductase ◽  
Time Analysis ◽  
Electron Transfer Reactions ◽  
P450 Reductase ◽  
Real Time Analysis ◽  
Human Cytochrome

Electron transfer in human cytochrome P450 reductase

2003 ◽  
Vol 31 (3) ◽  
pp. 497-501 ◽  
Author(s):  
A. Gutierrez ◽  
A. Grunau ◽  
M. Paine ◽  
A.W. Munro ◽  
C.R. Wolf ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Cytochrome P450 ◽  
Site Directed Mutagenesis ◽  
Cytochrome P450 Reductase ◽  
Cytochrome P450 Enzymes ◽  
P450 Reductase ◽  
Human Cytochrome ◽  
Redox Potentiometry ◽  
Electron Donation

Cytochrome P450 reductase (CPR) is a diflavin enzyme responsible for electron donation to mammalian cytochrome P450 enzymes in the endoplasmic reticulum. Dissection of the enzyme into functional domains and studies by site-directed mutagenesis have enabled detailed characterization of the mechanism of electron transfer using stopped-flow and equilibrium-perturbation methods, and redox potentiometry. These studies and the mechanism of electron transfer in CPR are reported herein.

Electron transfer in human cytochrome P450 reductase

2001 ◽  
Vol 29 (1) ◽  
pp. A9-A9
Author(s):  
N. S. Scrutton ◽  
A. Gutierrez ◽  
G. C. K. Roberts
Keyword(s):  
Electron Transfer ◽  
Cytochrome P450 ◽  
Cytochrome P450 Reductase ◽  
P450 Reductase ◽  
Human Cytochrome

Construction ofSalmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase

2001 ◽  
Vol 38 (4) ◽  
pp. 329-338 ◽  
Author(s):  
Ken-ichi Fujita ◽  
Kazuo Nakayama ◽  
Yoshiyuki Yamazaki ◽  
Kazuhiro Tsuruma ◽  
Masami Yamada ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 Reductase ◽  
Nadph Cytochrome ◽  
P450 Reductase ◽  
Human Cytochrome ◽  
Nadph Cytochrome P450 Reductase
Sign in / Sign up

Export Citation Format

Share Document