scholarly journals Epigenetic regulation of cellular functions in wound healing

2021 ◽  
Author(s):  
Irena Pastar ◽  
Jelena Marjanovic ◽  
Rivka C. Stone ◽  
Vivien Chen ◽  
Jamie L. Burgess ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Pawel Olczyk ◽  
Łukasz Mencner ◽  
Katarzyna Komosinska-Vassev

Wound healing is the physiologic response to tissue trauma proceeding as a complex pathway of biochemical reactions and cellular events, secreted growth factors, and cytokines. Extracellular matrix constituents are essential components of the wound repair phenomenon. Firstly, they create a provisional matrix, providing a structural integrity of matrix during each stage of healing process. Secondly, matrix molecules regulate cellular functions, mediate the cell-cell and cell-matrix interactions, and serve as a reservoir and modulator of cytokines and growth factors’ action. Currently known mechanisms, by which extracellular matrix components modulate each stage of the process of soft tissue remodeling after injury, have been discussed.


2014 ◽  
Vol 22 (3) ◽  
pp. 305-312 ◽  
Author(s):  
Dongdong Ti ◽  
Meirong Li ◽  
Xiaobing Fu ◽  
Weidong Han

2015 ◽  
Vol 17 (1) ◽  
pp. 16 ◽  
Author(s):  
Sabita Saldanha ◽  
Kendra Royston ◽  
Neha Udayakumar ◽  
Trygve Tollefsbol

2018 ◽  
Vol 216 (2) ◽  
pp. 253-266 ◽  
Author(s):  
Yuxiang Zheng ◽  
Lewis C. Cantley

Folate metabolism is crucial for many biochemical processes, including purine and thymidine monophosphate (dTMP) biosynthesis, mitochondrial protein translation, and methionine regeneration. These biochemical processes in turn support critical cellular functions such as cell proliferation, mitochondrial respiration, and epigenetic regulation. Not surprisingly, abnormal folate metabolism has been causally linked with a myriad of diseases. In this review, we provide a historical perspective, delve into folate chemistry that is often overlooked, and point out various missing links and underdeveloped areas in folate metabolism for future exploration.


2020 ◽  
Vol 72 (1) ◽  
pp. e260
Author(s):  
Frank M. Davis ◽  
Aaron Dendekker ◽  
Amrita Joshi ◽  
Sonya Wolf ◽  
Bethany Moore ◽  
...  

2013 ◽  
Vol 25 (1) ◽  
pp. 101-107 ◽  
Author(s):  
Jelena Mann ◽  
Derek A. Mann

2020 ◽  
Vol 28 (6) ◽  
pp. 710-718 ◽  
Author(s):  
Christopher J. Lewis ◽  
Andrew Stevenson ◽  
Mark W. Fear ◽  
Fiona M. Wood

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201975 ◽  
Author(s):  
Tram T. Vuong ◽  
Sissel B. Rønning ◽  
Tamer A. E. Ahmed ◽  
Kristiane Brathagen ◽  
Vibeke Høst ◽  
...  

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