scholarly journals MORE THAN ONE WAY TO PRODUCE PROTEIN DIVERSITY: DUPLICATION AND LIMITED ALTERNATIVE SPLICING OF AN ADHESION MOLECULE GENE IN BASAL ARTHROPODS

Evolution ◽  
2013 ◽  
pp. n/a-n/a ◽  
Author(s):  
Daniela Brites ◽  
Carlo Brena ◽  
Dieter Ebert ◽  
Louis Du Pasquier
Keyword(s):  
Alternative Splicing ◽  
Adhesion Molecule ◽  
Protein Diversity ◽  
Adhesion Molecule Gene

Ethanol Increases Fetal Human Neurosphere Size and Alters Adhesion Molecule Gene Expression

2008 ◽  
Vol 32 (2) ◽  
pp. 339-347 ◽  
Author(s):  
Sharada D. Vangipuram ◽  
William E. Grever ◽  
Graham C. Parker ◽  
William D. Lyman
Keyword(s):  
Gene Expression ◽  
Adhesion Molecule ◽  
Adhesion Molecule Gene

Abstract 353: Mechanical (or “Gravitational”) Unloading Reduces Inflammatory and Cell Adhesion Molecule Gene Expression in Human Endothelial Cells

2012 ◽  
Vol 32 (suppl_1) ◽  
Author(s):  
S Marlene Grenon ◽  
Jesus Aguado-Zuniga ◽  
Michael Conte ◽  
Millie Hughes-Fulford
Keyword(s):  
Gene Expression ◽  
Endothelial Cells ◽  
Adhesion Molecule ◽  
Cell Function ◽  
Quantitative Polymerase Chain Reaction ◽  
Cellular Interactions ◽  
Gravitational Unloading ◽  
Experimental Conditions ◽  
Adhesion Molecule Gene ◽  
The Impact

Objectives: Mechanical forces including gravity affect mechanotransduction and subsequent cell function. The goal of this study was to investigate the impact of mechanical unloading (MU) and loading (ML) of endothelial cells (ECs) with microgravity and hypergravity respectively, with the hypothesis that MU alters expression of inflammatory and adhesion molecule gene expression and these changes are reversed by ML. Methods: Human umbilical vascular endothelial cells (HUVECs) grown to confluency were studied. A desktop random positioning machine and a gravitational cell-loading apparatus provided MU and ML conditions, respectively. The experimental conditions included: 1) controls exposed to 1-gravity environment for 24 h (CL), 2) MU for 24 hours, 3) MU for 24 hours with three 30-minutes periods of ML of 12-gravity (MU/ML). Gene expression was studied with reverse transcription followed by real-time quantitative polymerase chain reaction (qRTPCR). Results: MU led to a significant decrease in gene expression of the adhesion molecules ICAM-1, VCAM-1, E-Selectin, as well as TNF-α, IL-6 and VEGF. In contrast, NOS-3, Caveolin-1 and -2 were significantly increased with MU. The changes observed in gene expression with MU were reversed by gravitational mechanical loading (MU/ML). Conclusions: Gravitational MU decreases inflammatory and adhesion molecule gene expression and these changes are reversed by short periods of ML. This points towards the importance of gravitational loading in ECs function and cellular interactions.

Herpes virus OsHV-1 and the protistPerkinsus marinusmodify the expression of the Down syndrome cell adhesion molecule gene in gill and mantle ofCrassostreaspp.

2018 ◽  
Vol 49 (11) ◽  
pp. 3638-3646 ◽  
Author(s):  
Lilián Arzeta-Pino ◽  
Armando Acosta ◽  
Maria E. Sarmiento ◽  
Maurilia Rojas-Contreras ◽  
Carmen Rodríguez-Jaramillo ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Cell Adhesion Molecule ◽  
Herpes Virus ◽  
Adhesion Molecule Gene ◽  
Herpès Virus

A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population

2002 ◽  
Vol 29 (2) ◽  
pp. 109-111 ◽  
Author(s):  
R. A. Gbadegesin ◽  
C. J. Watson ◽  
S. A. Cotton ◽  
P. E. C. Brenchley ◽  
N. J. A. Webb
Keyword(s):  
Adhesion Molecule ◽  
Gene Polymorphisms ◽  
Allele Frequencies ◽  
Typing Method ◽  
Pcr Rflp ◽  
Adhesion Molecule Gene ◽  
Rflp Typing
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