scholarly journals Peri‐ictal hypoxia is related to extent of regional brain volume loss accompanying generalized tonic‐clonic seizures

Epilepsia ◽  
2020 ◽  
Vol 61 (8) ◽  
pp. 1570-1580
Author(s):  
Luke A. Allen ◽  
Ronald M. Harper ◽  
Sjoerd B. Vos ◽  
Catherine A. Scott ◽  
Nuria Lacuey ◽  
...  
2016 ◽  
Vol 26 (5) ◽  
pp. 532-538 ◽  
Author(s):  
Angela Vidal-Jordana ◽  
Jaume Sastre-Garriga ◽  
Francisco Pérez-Miralles ◽  
Deborah Pareto ◽  
Jordi Rio ◽  
...  

2019 ◽  
Vol 267 (2) ◽  
pp. 395-405
Author(s):  
Juichi Fujimori ◽  
Kazuo Fujihara ◽  
Ryo Ogawa ◽  
Toru Baba ◽  
Mike Wattjes ◽  
...  

2015 ◽  
Vol 168 (1-2) ◽  
pp. 297-304 ◽  
Author(s):  
Joyce Y. Guo ◽  
Sanna Huhtaniska ◽  
Jouko Miettunen ◽  
Erika Jääskeläinen ◽  
Vesa Kiviniemi ◽  
...  

2011 ◽  
Vol 70 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Wen-Chun J Lan ◽  
Matthew Priestley ◽  
Sonia R Mayoral ◽  
Lu Tian ◽  
Mehrdad Shamloo ◽  
...  

2007 ◽  
Vol 8 (6) ◽  
pp. 328-336 ◽  
Author(s):  
Jan Kassubek ◽  
Freimut D. Juengling ◽  
Annette Baumgartner ◽  
Alexander Unrath ◽  
Albert C. Ludolph ◽  
...  

2017 ◽  
Vol 25 (4) ◽  
pp. 541-553 ◽  
Author(s):  
Tomas Uher ◽  
Manuela Vaneckova ◽  
Jan Krasensky ◽  
Lukas Sobisek ◽  
Michaela Tyblova ◽  
...  

Background: Volumetric MRI surrogate markers of disease progression are lacking. Objective: To establish cut-off values of brain volume loss able to discriminate between healthy controls and MS patients. Methods: In total, 386 patients after first demyelinating event suggestive of MS (CIS), 964 relapsing-remitting MS (RRMS) patients, 63 secondary-progressive MS (SPMS) patients and 58 healthy controls were included in this longitudinal study. A total of 11,438 MRI scans performed on the same MRI scanner with the same protocol were analysed. Annualised percentage changes of whole brain, grey matter, thalamus and corpus callosum volumes were estimated. We investigated cut-offs able to discriminate between healthy controls and MS patients. Results: At a predefined specificity of 90%, the annualised percentage change cut-off of corpus callosum volume (−0.57%) was able to distinguish between healthy controls and patients with the highest sensitivity (51% in CIS, 48% in RRMS and 42% in SPMS patients). Lower sensitivities (22%−49%) were found for cut-offs of whole brain, grey matter and thalamic volume loss. Among CIS and RRMS patients, cut-offs were associated with greater accumulation of disability. Conclusion: We identified cut-offs of annualised global and regional brain volume loss rates able to discriminate between healthy controls and MS patients.


2017 ◽  
Vol 128 (10) ◽  
pp. e328
Author(s):  
O. Vintonyak ◽  
M. Gorges ◽  
H.P. Müller ◽  
E.H. Pinkhardt ◽  
A.C. Ludolph ◽  
...  

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