A longitudinal cohort study on the impact of the clobazam shortage on patients with epilepsy

Epilepsia ◽  
2017 ◽  
Vol 59 (2) ◽  
pp. 468-478 ◽  
Author(s):  
Sara Lukmanji ◽  
Khara M. Sauro ◽  
Colin B. Josephson ◽  
K. Chelsea Altura ◽  
Samuel Wiebe ◽  
...  
Keyword(s):  
Cohort Study ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort ◽  
Patients With Epilepsy ◽  
The Impact

scholarly journals Adolescent depression, early psychiatric comorbidities, and adulthood welfare burden: a 25-year longitudinal cohort study

2021 ◽  
Author(s):  
Iman Alaie ◽  
Richard Ssegonja ◽  
Anna Philipson ◽  
Anne-Liis von Knorring ◽  
Margareta Möller ◽  
...  
Keyword(s):  
Cohort Study ◽  
Early Life ◽  
Adolescent Depression ◽  
Longitudinal Cohort Study ◽  
Health Concern ◽  
Psychiatric Comorbidities ◽  
Longitudinal Cohort ◽  
Transfer Payments ◽  
Social Transfer ◽  
The Impact

Abstract Purpose Depression at all ages is recognized as a global public health concern, but less is known about the welfare burden following early-life depression. This study aimed to (1) estimate the magnitude of associations between depression in adolescence and social transfer payments in adulthood; and (2) address the impact of major comorbid psychopathology on these associations. Methods This is a longitudinal cohort study of 539 participants assessed at age 16–17 using structured diagnostic interviews. An ongoing 25-year follow-up linked the cohort (n = 321 depressed; n = 218 nondepressed) to nationwide population-based registries. Outcomes included consecutive annual data on social transfer payments due to unemployment, work disability, and public assistance, spanning from age 18 to 40. Parameter estimations used the generalized estimating equations approach. Results Adolescent depression was associated with all forms of social transfer payments. The estimated overall payment per person and year was 938 USD (95% CI 551–1326) over and above the amount received by nondepressed controls. Persistent depressive disorder was associated with higher recipiency across all outcomes, whereas the pattern of findings was less clear for subthreshold and episodic major depression. Moreover, depressed adolescents presenting with comorbid anxiety and disruptive behavior disorders evidenced particularly high recipiency, exceeding the nondepressed controls with an estimated 1753 USD (95% CI 887–2620). Conclusion Adolescent depression is associated with considerable public expenditures across early-to-middle adulthood, especially for those exposed to chronic/persistent depression and psychiatric comorbidities. This finding suggests that the clinical heterogeneity of early-life depression needs to be considered from a longer-term societal perspective.

scholarly journals The impact of the Safer Anaesthesia from Education (SAFE) Obstetric Anaesthesia training course in Ethiopia: A mixed methods longitudinal cohort study

2020 ◽  
Vol 48 (4) ◽  
pp. 297-305
Author(s):  
Jolene N Moore ◽  
Wayne W Morriss ◽  
Gebrehiwot Asfaw ◽  
Gosa Tesfaye ◽  
Aaliya R Ahmed ◽  
...  
Keyword(s):  
Cohort Study ◽  
Mixed Methods ◽  
Maternal Mortality ◽  
Longitudinal Cohort Study ◽  
Structured Interviews ◽  
Middle Income ◽  
Longitudinal Cohort ◽  
Obstetric Anaesthesia ◽  
The Impact

Summary Reducing maternal mortality remains a global priority, particularly in low- and middle-income countries (LMICs). The Safer Anaesthesia from Education (SAFE) Obstetric Anaesthesia (OB) course is a three-day refresher course for trained anaesthesia providers addressing common causes of maternal mortality in LMICs. This aim of this study was to investigate the impact of SAFE training for a cohort of anaesthesia providers in Ethiopia. We conducted a mixed methods longitudinal cohort study incorporating a behavioural questionnaire, multiple-choice questionnaires (MCQs), structured observational skills tests and structured interviews for anaesthesia providers who attended one of four SAFE-OB courses conducted in two regions of Ethiopia from October 2017 to May 2018. Some 149 participants from 60 facilities attended training. Behavioural questionnaires were completed at baseline ( n = 101, 69% response rate). Pre- and post-course MCQs ( n = 121, n = 123 respectively) and pre- and post-course skills tests ( n = 123, n = 105 respectively) were completed, with repeat MCQ and skills tests, and semi-structured interviews completed at follow-up ( n = 88, n = 76, n = 49 respectively). The mean MCQ scores for all participants improved from 80.3% prior to training to 85.4% following training ( P < 0.0001) and skills test scores improved from 56.5% to 83.2% ( P < 0.0001). Improvements in MCQs and skills were maintained at follow-up 3–11 months post-training compared to baseline ( P = 0.0006, < 0.0001 respectively). Participants reported improved confidence, teamwork and communication at follow-up. This study suggests that the SAFE-OB course can have a sustained impact on knowledge and skills and can improve the confidence of anaesthesia providers and communication within surgical teams.

scholarly journals The impact of antiretroviral therapy on symptom burden among HIV outpatients with low CD4 count in rural Uganda: nested longitudinal cohort study

2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Katie Wakeham ◽  
Richard Harding ◽  
Jonathan Levin ◽  
Rosalind Parkes-Ratanshi ◽  
Anatoli Kamali ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antiretroviral Therapy ◽  
Symptom Burden ◽  
Cd4 Count ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort ◽  
The Impact

scholarly journals The Impact of Child Behaviour Problems on Maternal Employment: A Longitudinal Cohort Study

2013 ◽  
Vol 35 (3) ◽  
pp. 351-361 ◽  
Author(s):  
Ragnhild Bang Nes ◽  
Lars Johan Hauge ◽  
Tom Kornstad ◽  
Petter Kristensen ◽  
Markus A. Landolt ◽  
...  
Keyword(s):  
Cohort Study ◽  
Maternal Employment ◽  
Child Behaviour ◽  
Longitudinal Cohort Study ◽  
Behaviour Problems ◽  
Longitudinal Cohort ◽  
Child Behaviour Problems ◽  
The Impact

scholarly journals A longitudinal cohort study of the impact of first- and both-eye cataract surgery on falls and other injuries in Vietnam

2014 ◽  
pp. 743 ◽  
Author(s):  
Michelle Fraser ◽  
Lynn Meuleners ◽  
Max Bulsara ◽  
Dat Van Duong ◽  
Dung Van Do ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cataract Surgery ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort ◽  
The Impact
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