Seizure outcome after hippocampal deep brain stimulation in patients with refractory temporal lobe epilepsy: A prospective, controlled, randomized, double-blind study

Epilepsia ◽  
2017 ◽  
Vol 58 (10) ◽  
pp. 1728-1733 ◽  
Author(s):  
Arthur Cukiert ◽  
Cristine Mella Cukiert ◽  
Jose Augusto Burattini ◽  
Pedro Paulo Mariani ◽  
Daniela Fontes Bezerra
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Blind Study ◽  
Seizure Outcome ◽  
Double Blind Study ◽  
Double Blind ◽  
Deep Brain

scholarly journals Seizure outcome after hippocampal deep brain stimulation in a prospective cohort of patients with refractory temporal lobe epilepsy

Seizure ◽  
2014 ◽  
Vol 23 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Arthur Cukiert ◽  
Cristine Mella Cukiert ◽  
Jose Augusto Burattini ◽  
Alessandra Moura Lima
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Prospective Cohort ◽  
Seizure Outcome ◽  
Deep Brain

A double-blind study on a patient with tardive dyskinesia treated with pallidal deep brain stimulation

2009 ◽  
Vol 119 (4) ◽  
pp. 269-273 ◽  
Author(s):  
Z. Kefalopoulou ◽  
A. Paschali ◽  
E. Markaki ◽  
P. Vassilakos ◽  
J. Ellul ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Tardive Dyskinesia ◽  
Brain Stimulation ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Pallidal Deep Brain Stimulation ◽  
Deep Brain

The cognitive effects of amygdalohippocampal deep brain stimulation in patients with temporal lobe epilepsy

2011 ◽  
Vol 22 (4) ◽  
pp. 759-764 ◽  
Author(s):  
Marijke Miatton ◽  
Dirk Van Roost ◽  
Evert Thiery ◽  
Evelien Carrette ◽  
Annelies Van Dycke ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Cognitive Effects ◽  
Deep Brain

Deep Brain Stimulation in Patients with Refractory Temporal Lobe Epilepsy

Epilepsia ◽  
2007 ◽  
Vol 48 (8) ◽  
pp. 1551-1560 ◽  
Author(s):  
Paul Boon ◽  
Kristl Vonck ◽  
Veerle De Herdt ◽  
Annelies Van Dycke ◽  
Maarten Goethals ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Deep Brain

scholarly journals Hippocampal deep brain stimulation in nonlesional refractory mesial temporal lobe epilepsy

Seizure ◽  
2016 ◽  
Vol 37 ◽  
pp. 1-7 ◽  
Author(s):  
Hongbo Jin ◽  
Wenling Li ◽  
Changzheng Dong ◽  
Jiang Wu ◽  
Wenqing Zhao ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Mesial Temporal Lobe Epilepsy ◽  
Mesial Temporal Lobe ◽  
Deep Brain

A DOUBLE BLIND STUDY OF CARBAMAZEPINE AND DIPHENYLHYDANTOIN IN TEMPORAL LOBE EPILEPSY

1975 ◽  
Vol 51 ◽  
pp. 39-42 ◽  
Author(s):  
Niels Simonsen ◽  
Poul Zander Olsen ◽  
Viggo Kühl ◽  
Mogens Lund ◽  
Jørgen Wendelboe
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind

scholarly journals Long-term Deep Brain Stimulation for Refractory Temporal Lobe Epilepsy

Epilepsia ◽  
2005 ◽  
Vol 46 (s5) ◽  
pp. 98-99 ◽  
Author(s):  
Kristl Vonck ◽  
Paul Boon ◽  
Pieter Claeys ◽  
Stefanie Dedeurwaerdere ◽  
Rik Achten ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Brain Stimulation ◽  
Deep Brain

Cerebellar stimulation in the management of medically intractable epilepsy: a systematic and critical review

2010 ◽  
Vol 29 (2) ◽  
pp. E8 ◽  
Author(s):  
Kostas N. Fountas ◽  
Eftychia Kapsalaki ◽  
Georgios Hadjigeorgiou
Keyword(s):  
Deep Brain Stimulation ◽  
Seizure Frequency ◽  
Brain Stimulation ◽  
Clinical Studies ◽  
Intractable Epilepsy ◽  
Implantation Technique ◽  
Seizure Outcome ◽  
Double Blind ◽  
Deep Brain ◽  
Cerebellar Stimulation

Object The wide application of deep brain stimulation in the management of movement as well as other degenerative neurological and psychiatric disorders has renewed the interest in using deep brain stimulation in the management of medically intractable epilepsy. Various stimulation targets have been used with significantly varying results in aborting seizure activity. Electrical cerebellar stimulation (CS) has been used for more than 50 years in the management of epilepsy, with conflicting results. In the current study, the authors review the pertinent literature to outline the role of CS in the management of medically refractory epilepsy. Methods The PubMed medical database was systematically searched for the following terms: “cerebellar,” “epilepsy,” “stimulation,” and “treatment,” and all their combinations. Case reports were excluded from this study. Results The pertinent articles were categorized into 2 large groups: animal experimental and human clinical studies. Particular emphasis on the following aspects was given when reviewing the human clinical studies: their methodological characteristics, the number of participants, their seizure types, the implantation technique and its associated complications, the exact stimulation target, the stimulation technique, the seizure outcome, and the patients' psychological and social poststimulation status. Three clinical double-blind studies were found, with similar implantation surgical technique, stimulation target, and stimulation parameters, but quite contradictory results. Two of these studies failed to demonstrate any significant seizure reduction, whereas the third one showed a significant poststimulation decrease in seizure frequency. All possible factors responsible for these differences in the findings are analyzed in the present study. Conclusions Cerebellar stimulation seems to remain a stimulation target worth exploring for defining its potential in the treatment of medically intractable epilepsy, although the data from the double-blind clinical studies that were performed failed to establish a clear benefit in regard to seizure frequency. A large-scale, double-blind clinical study is required for accurately defining the efficacy of CS in epilepsy treatment.

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