Placental passage of antiepileptic drugs at delivery and neonatal outcomes

Anna M. Bank; Zachary N. Stowe; D. Jeffrey Newport; James C. Ritchie; Page B. Pennell

doi:10.1111/epi.13733

Placental passage of antiepileptic drugs at delivery and neonatal outcomes

Epilepsia ◽

10.1111/epi.13733 ◽

2017 ◽

Vol 58 (5) ◽

pp. e82-e86 ◽

Cited By ~ 6

Author(s):

Anna M. Bank ◽

Zachary N. Stowe ◽

D. Jeffrey Newport ◽

James C. Ritchie ◽

Page B. Pennell

Keyword(s):

Antiepileptic Drugs ◽

Neonatal Outcomes ◽

Placental Passage

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Differential effects of antiepileptic drugs on neonatal outcomes

Epilepsy & Behavior ◽

10.1016/j.yebeh.2012.05.010 ◽

2012 ◽

Vol 24 (4) ◽

pp. 449-456 ◽

Cited By ~ 34

Author(s):

P.B. Pennell ◽

A.M. Klein ◽

N. Browning ◽

G.A. Baker ◽

J. Clayton-Smith ◽

...

Keyword(s):

Antiepileptic Drugs ◽

Neonatal Outcomes ◽

Differential Effects

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A 27-Year-Old Woman with Epilepsy Planning for Pregnancy

10.1093/med/9780190609917.003.0028 ◽

2017 ◽

Author(s):

P. Emanuela Voinescu

Keyword(s):

Adverse Effects ◽

Antiepileptic Drugs ◽

Neonatal Outcomes ◽

Preconception Counseling ◽

Childbearing Age ◽

Adverse Neonatal Outcomes ◽

Neurodevelopmental Problems ◽

Remarkable Progress ◽

Made In

Treatment for women with epilepsy (WWE) of childbearing age should be cautiously selected, given that the benefits of treatment during potential future pregnancies have to be weighed against the adverse effects on the developing fetus. The number of antiepileptic drugs (AEDs) has increased significantly in the last 20 years, and remarkable progress has been made in characterizing their teratogenicity, adverse neonatal outcomes, and neurodevelopmental problems. Not only the AED choice, but the number of AEDs used and their dose are also important. This chapter aims to introduce some of the basic guidelines for preconception counseling.

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