scholarly journals Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential

Epilepsia ◽  
2013 ◽  
Vol 55 (2) ◽  
pp. 353-361 ◽  
Author(s):  
Tawfeeq Shekh-Ahmad ◽  
Naama Hen ◽  
Boris Yagen ◽  
John H. McDonough ◽  
Richard H. Finnell ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Pharmacokinetic Analysis ◽  
Active Derivative ◽  
Teratogenic Potential

Pharmacokinetic analysis and anticonvulsant activity of two polyesteric prodrugs of valproic acid

1993 ◽  
Vol 14 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Salim Hadad ◽  
Tom B. Vree ◽  
Eppo Van Der Kleijn ◽  
Meir Bialer
Keyword(s):  
Valproic Acid ◽  
Anticonvulsant Activity ◽  
Pharmacokinetic Analysis

Pharmacokinetic analysis of valdice — a diethylcarbonate prodrug of valproic acid

1994 ◽  
Vol 2 (3) ◽  
pp. 239-244 ◽  
Author(s):  
Meir Bialer ◽  
Zharura Pharaj ◽  
Shulamit Zuckerman ◽  
Itamar Raz ◽  
Oded Abramsky ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Pharmacokinetic Analysis

Stereoselective Pharmacokinetic Analysis of Valnoctamide, a CNS-Active Chiral Amide Analogue of Valproic Acid, in Dogs, Rats, and Mice

2000 ◽  
Vol 22 (5) ◽  
pp. 574-581 ◽  
Author(s):  
Ofer Spiegelstein ◽  
Boris Yagen ◽  
Gregory D. Bennett ◽  
Richard H. Finnell ◽  
Simcha Blotnik ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Pharmacokinetic Analysis ◽  
Rats And Mice

Predicting the human teratogenic potential of the anticonvulsant, valproic acid, from a non-human primate model

Toxicology ◽  
1986 ◽  
Vol 39 (2) ◽  
pp. 111-119 ◽  
Author(s):  
Terryl J. Mast ◽  
Mark A. Cukierski ◽  
Heinz Nau ◽  
Andrew G. Hendrickx
Keyword(s):  
Valproic Acid ◽  
Primate Model ◽  
Teratogenic Potential ◽  
Human Teratogenic Potential ◽  
Human Primate

Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide — Amide derivatives of valproic acid

2015 ◽  
Vol 46 ◽  
pp. 72-78 ◽  
Author(s):  
Hafiz Mawasi ◽  
Tawfeeq Shekh-Ahmad ◽  
Richard H. Finnell ◽  
Bogdan J. Wlodarczyk ◽  
Meir Bialer
Keyword(s):  
Valproic Acid ◽  
Pharmacokinetic Analysis ◽  
Amide Derivatives ◽  
Derivatives Of

scholarly journals Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid

Epilepsia ◽  
2014 ◽  
Vol 55 (12) ◽  
pp. 1944-1952 ◽  
Author(s):  
Tawfeeq Shekh-Ahmad ◽  
Hafiz Mawasi ◽  
John H. McDonough ◽  
Richard H. Finnell ◽  
Bogdan J. Wlodarczyk ◽  
...  
Keyword(s):  
Valproic Acid ◽  
Pharmacokinetic Analysis ◽  
Derivatives Of
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