Endothelin uncouples gap junctions in sustentacular cells and olfactory ensheathing cells of the olfactory mucosa

2014 ◽  
Vol 40 (6) ◽  
pp. 2878-2887 ◽  
Author(s):  
Mikaël Le Bourhis ◽  
Stéphanie Rimbaud ◽  
Denise Grebert ◽  
Patrice Congar ◽  
Nicolas Meunier
Keyword(s):  
Gap Junctions ◽  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Sustentacular Cells ◽  
Ensheathing Cells

OBTAINING OF CELLULAR PREPARATIONS OF RAT AND HUMAN OLFACTORY MUCOSA AND THEIR INFLUENCE ON THE SIZE OF MODELED SPINAL CORD CYSTALS

2021 ◽  
Vol 1 (19) ◽  
pp. 75-77
Author(s):  
O.V. Stepanova ◽  
E.K. Karsuntseva ◽  
G.A. Fursa ◽  
A.V. Chadin ◽  
M.P. Valikhov ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Progenitor Cells ◽  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Complete Disappearance ◽  
Ensheathing Cells ◽  
Neural Stem Progenitor Cells ◽  
Human Olfactory Mucosa ◽  
Enriched Cultures

Enriched cultures of olfactory ensheathing cells and neural stem/progenitor cells were obtained according to our developed protocols from the olfactory mucosa of rat and human. It has been shown that only transplantation of human and rat olfactory ensheathing cells leads to a significant decrease in the size of cysts, as well as their complete disappearance in some animals.

Panglial gap junctions between astrocytes and olfactory ensheathing cells mediate transmission of Ca 2+ transients and neurovascular coupling

Glia ◽  
2019 ◽  
Vol 67 (7) ◽  
pp. 1385-1400 ◽  
Author(s):  
Antonia Beiersdorfer ◽  
Anja Scheller ◽  
Frank Kirchhoff ◽  
Christian Lohr
Keyword(s):  
Gap Junctions ◽  
Neurovascular Coupling ◽  
Olfactory Ensheathing Cells ◽  
Ensheathing Cells

scholarly journals In vitro Maintenance of Olfactory Mucosa: with Enriched Olfactory Ensheathing Cells

2013 ◽  
Vol 03 (01) ◽  
Author(s):  
Neetu Singh ◽  
Saroj Chooramani Gopal ◽  
Rajeshwar Nath Srivastava ◽  
Tulika Chandra ◽  
Satya Prakash Agarwal
Keyword(s):  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Ensheathing Cells ◽  
In Vitro Maintenance

Calcium-induced calcium release and gap junctions mediate large-scale calcium waves in olfactory ensheathing cells in situ

Cell Calcium ◽  
2015 ◽  
Vol 58 (2) ◽  
pp. 215-225 ◽  
Author(s):  
Maren Stavermann ◽  
Patrick Meuth ◽  
Michael Doengi ◽  
Anne Thyssen ◽  
Joachim W. Deitmer ◽  
...  
Keyword(s):  
Gap Junctions ◽  
Large Scale ◽  
Calcium Release ◽  
Olfactory Ensheathing Cells ◽  
Calcium Waves ◽  
Ensheathing Cells ◽  
Calcium Induced Calcium Release

The olfactory bulb and olfactory mucosa obtained from human cadaver donors as a source of olfactory ensheathing cells

Glia ◽  
2006 ◽  
Vol 54 (6) ◽  
pp. 557-565 ◽  
Author(s):  
Ryszard Miedzybrodzki ◽  
Pawel Tabakow ◽  
Wojciech Fortuna ◽  
Bogdan Czapiga ◽  
Wlodzimierz Jarmundowicz
Keyword(s):  
Olfactory Bulb ◽  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Human Cadaver ◽  
Ensheathing Cells

scholarly journals High-Yield Mucosal Olfactory Ensheathing Cells Restore Loss of Function in Rat Dorsal Root Injury

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1186
Author(s):  
Kamile Minkelyte ◽  
Andrew Collins ◽  
Modinat Liadi ◽  
Ahmed Ibrahim ◽  
Daqing Li ◽  
...  
Keyword(s):  
Clinical Application ◽  
Fluorescent Protein ◽  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Functional Improvement ◽  
High Yield ◽  
Loss Of Function ◽  
Dorsal Rhizotomy ◽  
Ensheathing Cells ◽  
Green Fluorescent

In a previous study, we reported that no axons were crossing from the severed dorsal roots to the spinal cord using the rat dorsal rhizotomy paradigm. The injury caused ipsilateral deficits of forepaw function. An attempt to restore the function by transplanting cells containing 5% olfactory ensheathing cells (OECs) cultured from the olfactory mucosa did not succeed. However, obtaining OECs from the olfactory mucosa has an advantage for clinical application. In the present study, we used the same rhizotomy paradigm, but rats with an injury received cells from a modified mucosal culture containing around 20% OECs mixed in collagen. The forelimb proprioception assessment showed that 80% of the rats receiving the transplants had functional improvement over six weeks of the study. The adhesive removal test showed that the time taken for the rats to notice the adhesive label and remove it almost returned to the normal level after receiving the transplants. Transplanted cells were identified with the expression of green fluorescent protein (ZsGreen). Some regeneration fibres immunostained for neurofilament (NF) or traced by biotinylated dextran amine (BDA) in the injury area were associated with the transplanted cells. The evidence in this study improves the prospect of clinical application using OECs from the olfactory mucosa to treat CNS injuries.

Comparative gene expression profiling of olfactory ensheathing cells from olfactory bulb and olfactory mucosa

Glia ◽  
2010 ◽  
Vol 58 (13) ◽  
pp. 1570-1580 ◽  
Author(s):  
Nicolas Guérout ◽  
Céline Derambure ◽  
Laurent Drouot ◽  
Nicolas Bon-Mardion ◽  
Célia Duclos ◽  
...  
Keyword(s):  
Gene Expression ◽  
Olfactory Bulb ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Olfactory Mucosa ◽  
Olfactory Ensheathing Cells ◽  
Ensheathing Cells
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