scholarly journals Exploration of symptom dimensions and duration of untreated psychosis within a staging model of schizophrenia spectrum disorders

2020 ◽  
Author(s):  
Steven Berendsen ◽  
Henricus L. Van ◽  
Jasper W. Paardt ◽  
Olav R. Peuter ◽  
Marion Bruggen ◽  
...  
Keyword(s):  
Duration Of Untreated Psychosis ◽  
Schizophrenia Spectrum Disorders ◽  
Symptom Dimensions ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Staging Model

scholarly journals Clinical Staging in Schizophrenia Spectrum Disorders

2021 ◽  
Author(s):  
Zsófia Borbála Dombi ◽  
Ágota Barabássy ◽  
Barbara Sebe ◽  
István Laszlovszky ◽  
György Németh
Keyword(s):  
Gold Standard ◽  
State Of The Art ◽  
Treatment Strategies ◽  
Clinical Staging ◽  
Schizophrenia Spectrum Disorders ◽  
The Past ◽  
Schizophrenia Spectrum ◽  
Appropriate Treatment ◽  
Spectrum Disorders ◽  
Staging Model

The aim of this chapter is to summarize the state-of-the-art knowledge of clinical staging in schizophrenia spectrum disorders. Clinical staging has been introduced to psychiatry in the past two decades. Its primary goal is to divide the course of the disorder into recognizable stages based on seriousness, development and symptom characteristics in order to better predict prognosis and to adopt the most appropriate treatment strategies. The first staging model was developed in 1982. Since then several distinct concepts of clinical staging in psychiatry have emerged. To date, there is no clinical consensus regarding which staging model is the gold standard, nonetheless when merging them together an integrated staging concept arises. The integrated staging model of schizophrenia spectrum disorders is composed of four stages. The chapter will introduce the different staging models in a historical order as well as present the integrated staging model detailing the characteristics, timeline and dominating symptoms of each stage. Appropriate treatment strategies for the distinct stages will also be outlined.

“Pseudoneurotic Schizophrenia” Revisited: The role of obsessive-compulsive symptoms in low-level disorganization psychosishosiser

2017 ◽  
Vol 41 (S1) ◽  
pp. s841-s841
Author(s):  
M. Tonna ◽  
R. Ottoni ◽  
F. Paglia ◽  
C. De Panfilis ◽  
C. marchesi
Keyword(s):  
Gradual Transition ◽  
Schizophrenia Spectrum Disorders ◽  
Obsessive Compulsive ◽  
Symptom Dimensions ◽  
Schizophrenia Spectrum ◽  
Obsessive Compulsive Symptom ◽  
Spectrum Disorders ◽  
Competing Interest ◽  
Levels Of Functioning

ObjectiveRecent research has suggested a dual impact of obsessive-compulsive dimension on functioning in schizophrenia with a gradual transition from an improving to a worsening effect depending on obsessive-compulsive symptom (OCS) severity (from mild to moderate-severe). Aim of the present study was to investigate whether this varying effect of OCS on functioning might be mediated or moderated by schizophrenia symptom dimensions or occur independently.MethodSeventy-five patients affected by schizophrenia were administered the SCID-IV, the PANSS, the YBOCS and the SOFAS.The sample was divided into two groups according to the severity of OCS (absent/mild and moderate/high).ResultsIn both groups, a significant interaction between OCS and disorganization dimension was found: the dual effect of OCS on functioning occurred only among patients with low disorganization symptoms while it was no more apparent at higher levels of disorganization (Figure 1).ConclusionData suggest that in patients with schizophrenia, functioning at least in part depends on the interaction between disorganization and OCS. Particularly, mild OCS contributes to higher levels of functioning in patients with psychosis at low levels of disorganization. In keeping with the historical concept of “pseudoneurotic schizophrenia”, we speculate that obsessive dimension might have a pathoplastic influence in milder forms of schizophrenia spectrum disorders, balancing the effect of underlying low disorganization symptoms.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Psychosis in Women: Time for Personalized Treatment

2021 ◽  
Vol 11 (12) ◽  
pp. 1279
Author(s):  
Marianna Mazza ◽  
Emanuele Caroppo ◽  
Domenico De Berardis ◽  
Giuseppe Marano ◽  
Carla Avallone ◽  
...  
Keyword(s):  
Great Part ◽  
Healthcare Services ◽  
Psychosocial Treatment ◽  
Schizophrenia Spectrum Disorders ◽  
Drug Induced ◽  
Clinical Onset ◽  
Schizophrenia Spectrum ◽  
Treatment Plans ◽  
Spectrum Disorders ◽  
Staging Model

Early detection and prompt treatment of psychosis is of the utmost importance. The great variability in clinical onset, illness course, and response to pharmacological and psychosocial treatment is in great part gender-related. Our aim has been to review narratively the literature focusing on gender related differences in the psychoses, i.e., schizophrenia spectrum disorders. We searched the PubMed/Medline, Scopus, Embase, and ScienceDirect databases on 31 July 2021, focusing on recent research regarding sex differences in early psychosis. Although women, compared to men, tend to have better overall functioning at psychotic symptom onset, they often present with more mood symptoms, may undergo misdiagnosis and delay in treatment and are at a higher risk for antipsychotic drug-induced metabolic and endocrine-induced side effects. Furthermore, women with schizophrenia spectrum disorders have more than double the odds of having physical comorbidities than men. Tailored treatment plans delivered by healthcare services should consider gender differences in patients with a diagnosis of psychosis, with a particular attention to early phases of disease in the context of the staging model of psychosis onset.

Screening Adolescents for Schizophrenia-Spectrum Disorders

2000 ◽  
Author(s):  
B. Cornblatt ◽  
M. Obuchowski ◽  
S. Roberts ◽  
S. Pollack ◽  
L. Erienmeyer-Kimling
Keyword(s):  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

Sleep and cognition in schizophrenia spectrum disorders: A systematic review protocol.

2020 ◽  
Author(s):  
Sean Carruthers ◽  
Gemma Brunetti ◽  
Susan Rossell
Keyword(s):  
Systematic Review ◽  
Mental Illnesses ◽  
Schizophrenia Spectrum Disorders ◽  
Systematic Review Protocol ◽  
Schizophrenia Spectrum Disorder ◽  
Schizophrenia Spectrum ◽  
Review Protocol ◽  
Spectrum Disorders ◽  
Sleep And Cognition ◽  
The Relationship

Schizophrenia spectrum disorders are chronic and debilitating mental illnesses characterised by both cognitive impairments and sleep deficits. In this systematic review protocol, we outline an approach to examine the available literature investigating the relationship between sleep and cognition in individuals with schizophrenia spectrum disorder.

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