Comparative evaluation of therapeutic efficacy and safety of intralesional triamcinolone acetonide injection vs intralesional radiofrequency with intralesional triamcinolone acetonide in treatment of keloids

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Vishw Kaushal ◽  
Sumir Kumar ◽  
Balwinder Kaur Brar ◽  
Amarbir Singh
Keyword(s):  
Triamcinolone Acetonide ◽  
Therapeutic Efficacy ◽  
Comparative Evaluation ◽  
Efficacy And Safety

Therapeutic Efficacy and Safety of Korean Red Ginseng During Cyclosporine Treatment.

2014 ◽  
Vol 98 ◽  
pp. 283
Author(s):  
S. Lim ◽  
K. Doh ◽  
L. Jin ◽  
S. Piao ◽  
S. Heo ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Efficacy And Safety ◽  
Red Ginseng ◽  
Korean Red Ginseng

scholarly journals Therapeutic Efficacy and Safety of Amitriptyline in Patients with Cystic Fibrosis

2009 ◽  
Vol 24 (1-2) ◽  
pp. 65-72 ◽  
Author(s):  
Joachim Riethmüller ◽  
Janina Anthonysamy ◽  
Emilio Serra ◽  
Matthias Schwab ◽  
Gerd Döring ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Therapeutic Efficacy ◽  
Efficacy And Safety

scholarly journals A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, andIn VivoAntitumor Efficacy and Safety

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Ying Wang ◽  
Ke-Chun Wu ◽  
Bing-Xiang Zhao ◽  
Xin Zhao ◽  
Xin Wang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Therapeutic Efficacy ◽  
Antitumor Efficacy ◽  
Allergic Reactions ◽  
Cremophor El ◽  
Efficacy And Safety ◽  
Tumor Bearing ◽  
Allergic Effect ◽  
Injection Product

The purpose of this study was to prepare a novel paclitaxel (PTX) microemulsion containing a reduced amount of Cremophor EL (CrEL) which had similar pharmacokinetics and antitumor efficacy as the commercially available PTX injection, but a significantly reduced allergic effect due to the CrEL. The pharmacokinetics, biodistribution,in vivoantitumor activity and safety of PTX microemulsion was evaluated. The results of pharmacokinetic and distribution properties of PTX in the microemulsion were similar to those of the PTX injection. The antitumor efficacy of the PTX microemulsion in OVCRA-3 and A 549 tumor-bearing animals was similar to that of PTX injection. The PTX microemulsion did not cause haemolysis, erythrocyte agglutination or simulative reaction. The incidence and degree of allergic reactions exhibited by the PTX microemulsion group, with or without premedication, were significantly lower than those in the PTX injection group (P<.01). In conclusion, the PTX microemulsion had similar pharmacokinetics and anti-tumor efficacy to the PTX injection, but a significantly reduced allergic effect due to CrEL, indicating that the PTX microemulsion overcomes the disadvantages of the conventional PTX injection and is one way of avoiding the limitations of current injection product while providing suitable therapeutic efficacy.

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