Utility of platelet rich fibrin gel therapy in nonhealing ulcer secondary to ecthyma gangrenosum

2019 ◽  
Vol 32 (3) ◽  
Author(s):  
Bandhala Rajan M ◽  
Saurabh Singh
2017 ◽  
Vol 33 (02) ◽  
pp. 225-232 ◽  
Author(s):  
Milos Kovacevic ◽  
Frank Riedel ◽  
Jochen Wurm ◽  
Gregor Bran

Multiple techniques have been described for dorsal nasal augmentation in rhinoplasty. In this article, we review common surgical techniques for raising the dorsum or eliminating dorsal irregularities, by highlighting inherent advantages and disadvantages of each method. Within the past few years, the use of diced cartilage grafts has become the workhorse in this field of interest. To overcome drawbacks of methods based on diced cartilage, we present a new concept for autologous augmentation, using regenerative medicine protocols. A mix of cartilage scales with cartilage pâté was embedded in platelet-rich fibrin (PRF). Since December 2015, a total of 48 patients were treated with this technique. Based on our preliminary results, cartilage scales in PRF appear to be a promising and reliable alternative to existing procedures for dorsal nasal augmentation.


2018 ◽  
Vol 173 ◽  
pp. 1-12 ◽  
Author(s):  
Gamze Dereli Can ◽  
Özge Ekin Akdere ◽  
Mehmet Erol Can ◽  
Bahri Aydın ◽  
Nurullah Cagil ◽  
...  

2014 ◽  
Vol 5 (3) ◽  
pp. 77-83
Author(s):  
Ebrahim Al-Khawlani ◽  
Osama Antar Adly ◽  
Tamer Abd Albari Hamed ◽  
Ashraf Hussein Abass ◽  
Abdelbadia Abdallah Abdelmabood

2021 ◽  
Vol 13 (2) ◽  
pp. 170-7
Author(s):  
Ronald Winardi Kartika ◽  
Idrus Alwi ◽  
Franciscus Dhyanagiri Suyatna ◽  
Em Yunir ◽  
Sarwono Waspadji ◽  
...  

BACKGROUND: Diabetic foot ulcer (DFU) is the most common and threatening complication of Diabetes Mellitus (DM). Ideal wound dressing for DFU management should relieve symptoms, provide wound protection, and encourage healing. Advanced-Platelet Rich Fibrin (A-PRF) and Hyaluronic Acid (HA) have been proven to improve wound healing process. This study was aimed to demonstrate the ability of combination of A-PRF and HA in reducing inflammation and improving DFU tissue healing.METHODS: Twenty DFU subjects were involved in this study, and divided into two groups based on the topical fibrin gel treatment: A-PRF + HA group and A-PRF only group. A-PRF was obtained by peripheral blood centrifugation. A-PRF + HA was prepared by homogening A-PRF and AH with a ratio of 1:0.6. Interleukin-6 (IL-6) level, granulation index (GI), numeric pain score (NPS), and inflammation clinical symptoms (ICS) were assessed on day-0, 3, 7 and 14.RESULTS: Wound swabs’ IL-6 level on day-7 was found to be significantly lower in A-PRF + HA compared to A-PRF alone (p=0.041). The IL-6 level reduction also found to be significant higher either in wound swabs (day 0-7, p=0.015) or fibrin gel (day 0-3, p=0.049; day 0-7, p=0.034). A-PRF + HA treatment significantly increased the GI even since day-3 (p=0.043), with lower NPS (p<0.001), and ICS score.CONCLUSION: The combination of A-PRF and HA increases the GI in DFU healing by reducing the inflammation state which will induce the angiogenesis process, as well as reducing pain in DFU subjects better than A-PRF alone.KEYWORDS: inflammation, interleukin-6, wound healing, angiogenesis, proliferation 


2012 ◽  
Vol 12 (1) ◽  
pp. 11-16 ◽  
Author(s):  
S. Girish Rao ◽  
Preethi Bhat ◽  
K. S. Nagesh ◽  
Gundu H. R. Rao ◽  
Bharthi Mirle ◽  
...  

2019 ◽  
Vol 47 (4) ◽  
pp. 455-462 ◽  
Author(s):  
Ruben Dukan ◽  
Aude Bommier ◽  
Marc-Antoine Rousseau ◽  
Patrick Boyer

2012 ◽  
Vol 100B (4) ◽  
pp. 948-955 ◽  
Author(s):  
Chi-Sheng Chien ◽  
Hsiu-O Ho ◽  
Yu-Chih Liang ◽  
Pai-Hung Ko ◽  
Ming-Thau Sheu ◽  
...  

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