In Vivo Reflectance Confocal Microscopy to Optimize the Spaghetti Technique for Defining Surgical Margins of Lentigo Maligna

2014 ◽  
Vol 40 (3) ◽  
pp. 247-256 ◽  
Author(s):  
Julie Champin ◽  
Jean-Luc Perrot ◽  
Elisa Cinotti ◽  
Bruno Labeille ◽  
Catherine Douchet ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Surgical Margins ◽  
Reflectance Confocal Microscopy ◽  
Lentigo Maligna

scholarly journals Comparing preoperative mapping with reflectance confocal microscopy to surgical markings in lentigo maligna excision of the face: a pilot study

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Lipi Shukla ◽  
Louise Photiou ◽  
Alan Pham ◽  
Catriona McLean ◽  
Raquel Ruiz ◽  
...  
Keyword(s):  
Pilot Study ◽  
Confocal Microscopy ◽  
Surgical Margin ◽  
Surgical Excision ◽  
Reflectance Confocal Microscopy ◽  
Histopathological Analysis ◽  
Lentigo Maligna ◽  
Complete Excision ◽  
Preoperative Mapping

Background: Lentigo maligna (LM) characteristically has an ill-defined margin and may require multiple excisions to achieve complete excision with 5mm margins. In vivo reflectance confocal microscopy (RCM) is a non-invasive tool recognised as useful in the management of LM. The authors aimed to determine whether the use of RCM prior to surgical excision reliably increased the rate of complete excision when compared with standard surgical excision. Methods: This prospective pilot study included patients with biopsy-proven LM of head and neck region who sought consultation for surgical management from May 2017 to May 2019 at the Victorian Melanoma Service, Melbourne. Patients were randomised to two groups based on the availability of RCM — Group 1, RCM-guided surgical excision, and Group 2, standard surgical excision. Outcomes were measured based on clinical markings and histopathological margins achieved and reported as RCM or surgical margin excess or deficit. Ethics approval for the study was obtained from the Research Governance Unit of The Alfred Hospital, Melbourne. Results: Results demonstrated that RCM marking of lesion margins was in excess in 69 percent of cases, in deficit in 22 per cent and accurate in nine per cent after histopathological analysis of the specimens. In comparison, lesions that were surgically marked were removed with margins in excess in 43 per cent of cases, in deficit in 11 per cent and accurate in 46 per cent. Conclusion: This pilot study demonstrates that RCM did not increase the accuracy of LM surgical excision in comparison with standard surgically marked excisions.

In vivo reflectance confocal microscopy to monitor the response of lentigo maligna to imiquimod

2014 ◽  
Vol 71 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Ivette Alarcon ◽  
Cristina Carrera ◽  
Llucia Alos ◽  
Josep Palou ◽  
Josep Malvehy ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Reflectance Confocal Microscopy ◽  
Lentigo Maligna

scholarly journals The Impact of In Vivo Reflectance Confocal Microscopy on the Diagnostic Accuracy of Lentigo Maligna and Equivocal Pigmented and Nonpigmented Macules of the Face

2010 ◽  
Vol 130 (8) ◽  
pp. 2080-2091 ◽  
Author(s):  
Pascale Guitera ◽  
Giovanni Pellacani ◽  
Kerry A. Crotty ◽  
Richard A. Scolyer ◽  
Ling-Xi L. Li ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Diagnostic Accuracy ◽  
Reflectance Confocal Microscopy ◽  
Lentigo Maligna ◽  
The Face ◽  
The Impact

scholarly journals Pigmented actinic lichen planus (PALP) mimicking lentigo maligna melanoma: Usefulness of in vivo reflectance confocal microscopy in diagnosis and follow-up

2018 ◽  
Vol 4 (6) ◽  
pp. 568-572 ◽  
Author(s):  
Marina Venturini ◽  
Ausilia Maria Manganoni ◽  
Arianna Zanca ◽  
Stefania Bassissi ◽  
Laura Pavoni ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Lichen Planus ◽  
Reflectance Confocal Microscopy ◽  
Lentigo Maligna ◽  
Lentigo Maligna Melanoma
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