scholarly journals Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy

2019 ◽  
Vol 61 (8) ◽  
pp. 924-928 ◽  
Author(s):  
Jennifer M Ryan ◽  
Mark D Peterson ◽  
Nicola Ryan ◽  
Kimberley J Smith ◽  
Neil E O'connell ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cerebral Palsy ◽  
Respiratory Disease

scholarly journals Noncommunicable disease among adults with cerebral palsy

Neurology ◽  
2019 ◽  
Vol 93 (14) ◽  
pp. e1385-e1396 ◽  
Author(s):  
Jennifer M. Ryan ◽  
Mark D. Peterson ◽  
Anthony Matthews ◽  
Nicola Ryan ◽  
Kimberley J. Smith ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Cerebral Palsy ◽  
Respiratory Disease ◽  
Noncommunicable Disease ◽  
Increased Risk ◽  
Risk Of Cancer

ObjectiveTo compare the incidence of noncommunicable diseases between adults with and without cerebral palsy (CP).MethodsA cohort study was conducted using primary care data from the Clinical Practice Research Datalink. Cox models, stratified by matched set and adjusted for potential confounders, were fitted to compare the risk of any noncommunicable disease, cancer, cardiovascular disease, type 2 diabetes mellitus, and respiratory disease between adults with and without CP.ResultsThe analysis included 1,705 adults with CP and 5,115 age-, sex-, and general practice–matched adults without CP. There was evidence from adjusted analyses that adults with CP had 75% increased risk of developing any noncommunicable disease compared to adults without CP (hazard ratio [HR] 1.75, 95% confidence interval [CI] 1.58–1.94). Specifically, they had increased risk of cardiovascular disease (HR 1.76, 95% CI 1.48–2.11) and respiratory disease (HR 2.61, 95% CI 2.14–3.19). There was no evidence of increased risk of cancer or type 2 diabetes mellitus.ConclusionsAdults with CP had increased risk of noncommunicable disease, specifically cardiovascular and respiratory disease. These findings highlight the need for clinical vigilance regarding identification of noncommunicable disease in people with CP and further research into the etiology and management of noncommunicable disease in this population.

scholarly journals Low‐Trauma Fracture Increases 12‐Month Incidence of Cardiovascular Disease for Adults With Cerebral Palsy

2019 ◽  
Vol 38 (4) ◽  
pp. 803-810 ◽  
Author(s):  
Daniel G. Whitney ◽  
Rachael T. Whitney ◽  
Rhonda D. Prisby ◽  
Karl J. Jepsen
Keyword(s):  
Cardiovascular Disease ◽  
Cerebral Palsy ◽  
Low Trauma Fracture

scholarly journals The Impact of Non-optimum Ambient Temperature on Years of Life Lost: A Multi-county Observational Study in Hunan, China

2020 ◽  
Vol 17 (8) ◽  
pp. 2699
Author(s):  
Ling-Shuang Lv ◽  
Dong-Hui Jin ◽  
Wen-Jun Ma ◽  
Tao Liu ◽  
Yi-Qing Xu ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Ambient Temperature ◽  
Respiratory Disease ◽  
Age Groups ◽  
The Elderly ◽  
Cold Temperature ◽  
Years Of Life Lost ◽  
Distributed Lag ◽  
Preventative Measures ◽  
The Impact

The ambient temperature–health relationship is of growing interest as the climate changes. Previous studies have examined the association between ambient temperature and mortality or morbidity, however, there is little literature available on the ambient temperature effects on year of life lost (YLL). Thus, we aimed to quantify the YLL attributable to non-optimum ambient temperature. We obtained data from 1 January 2013 to 31 December 2017 of 70 counties in Hunan, China. In order to combine the effects of each county, we used YLL rate as a health outcome indicator. The YLL rate was equal to the total YLL divided by the population of each county, and multiplied by 100,000. We estimated the associations between ambient temperature and YLL with a distributed lag non-linear model (DNLM) in a single county, and then pooled them in a multivariate meta-regression. The daily mean YLL rates were 22.62 y/(p·100,000), 10.14 y/(p·100,000) and 2.33 y/(p·100,000) within the study period for non-accidental, cardiovascular, and respiratory disease death. Ambient temperature was responsible for advancing a substantial fraction of YLL, with attributable fractions of 10.73% (4.36–17.09%) and 16.44% (9.09–23.79%) for non-accidental and cardiovascular disease death, respectively. However, the ambient temperature effect was not significantly for respiratory disease death, corresponding to 5.47% (−2.65–13.60%). Most of the YLL burden was caused by a cold temperature than the optimum temperature, with an overall estimate of 10.27% (4.52–16.03%) and 15.94% (8.82–23.05%) for non-accidental and cardiovascular disease death, respectively. Cold and heat temperature-related YLLs were higher in the elderly and females than the young and males. Extreme cold temperature had an effect on all age groups in different kinds of disease-caused death. This study highlights that general preventative measures could be important for moderate temperatures, whereas quick and effective measures should be provided for extreme temperatures.

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