scholarly journals Sleep disorders in children with Down syndrome

2013 ◽  
Vol 55 (7) ◽  
pp. 675-675 ◽  
Author(s):  
Tomoyuki Kawada
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Children With Down Syndrome

611 Sleep Disorders in a Longitudinal Community Cohort of Children with Down Syndrome

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A240-A240
Author(s):  
Nisha Patel ◽  
Timothy Morgenthaler ◽  
Julie Baughn
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Screening Tools ◽  
Treatment Needs ◽  
Cross Sectional Survey ◽  
Periodic Limb Movement Disorder ◽  
Cross Sectional ◽  
Children With Down Syndrome ◽  
Obstructive Sleep ◽  
Respiratory Sleep Disorders

Abstract Introduction Obstructive sleep apnea (OSA) affects 50–79% of children with Down Syndrome (CDS) prompting the development of guidelines to increase early detection of OSA. Cross-sectional survey based data shows that CDS have higher rates of bedtime resistance, sleep anxiety, night waking and parasomnias, which are also under-recognized. However, due to increased survival of CDS it may be that OSA treated in childhood returns or worsens, or that CDS may develop other sleep disorders as their life experience and exposure to comorbidities expands. Little is known about sleep disorders across the life span of CDS and screening guidelines leave a gap beyond early childhood. We determined to enhance understanding of respiratory and non-respiratory sleep disorders in a community population of CDS. Methods A retrospective population based observational study of CDS born between 1995–2011 was performed using the Rochester Epidemiology Project database. Medical records from all encounters through July 2020 were reviewed to identify sleep disorders. Sleep diagnoses, sleep test results, and treatments aimed at sleep disorders were recorded. Results 94 CDS were identified with 85 providing consent for research. 54 out of 85 individuals were diagnosed with OSA with 26 diagnosed prior to age 4 and 25 undergoing polysomnography prior to treatment. 26 individuals underwent polysomnography following surgery of which 16 continued to have clinically significant OSA requiring further treatment with secondary surgery, CPAP or anti-inflammatory therapy. Other sleep disorders observed included insomnia (n=16), restless leg syndrome (n=7), periodic limb movement disorder (n=10), idiopathic hypersomnia (n=1), nightmares (n=1), nocturnal enuresis (n=1), bruxism (n=1) and delayed sleep phase disorder (n=1). Most non-OSA sleep disorders were diagnosed during OSA evaluation by sleep medicine providers. However, many children were on melatonin without a formal sleep disorder diagnosis. Conclusion Both OSA and other sleep disorders remain under-diagnosed in CDS. This may be due to lack of validated screening tools that can be administered at the primary care level. Screening recommendations should consider the longitudinal nature of OSA in CDS and the presence of non-respiratory sleep disorders. Adenotonsillectomy is not as effective in CDS and postsurgical polysomnography is warranted along with long term follow-up to assess for further treatment needs. Support (if any):

scholarly journals Evaluation of Sleep Disorders in Children with Down Syndrome

2019 ◽  
Vol 20 (-1) ◽  
pp. 413-413
Author(s):  
Mina Gharibzadeh Hizal ◽  
◽  
Sanem Eryilmaz Polat ◽  
Dilber Ademhan ◽  
Nagehan Emiralioglu ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Children With Down Syndrome

Evaluation of Sleep Disorders In Children with Down Syndrome

2019 ◽  
Author(s):  
Mina Gharibzadeh Hizal ◽  
Sanem Eryılmaz Polat ◽  
Dilber Ademhsn ◽  
Nagehan Emiralioglu ◽  
Ozlem Kiper ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Children With Down Syndrome

scholarly journals Sleep, Function, Behaviour and Cognition in a Cohort of Children with Down Syndrome

2021 ◽  
Vol 11 (10) ◽  
pp. 1317
Author(s):  
Jasneek K Chawla ◽  
Anne Bernard ◽  
Helen Heussler ◽  
Scott Burgess
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Sleep Problem ◽  
Sleep Problems ◽  
Functional Impairments ◽  
Sleep Habits ◽  
Sleep Study ◽  
Children With Down Syndrome ◽  
Daytime Function ◽  
The Impact

Objective: To describe the sleep problems experienced by children with Down syndrome attending a tertiary sleep clinic and relationship with behaviour, function and cognition. Methods: Data were collected from children with Down syndrome aged 3–18 years old. Carers completed the Abbreviated Child Sleep Habits Questionnaire, Child Behaviour Checklist and Life-Habits Questionnaire at enrolment. Cognitive assessment (Stanford-Binet 5) was undertaken by a trained psychologist. Children received management for their sleep problem as clinically indicated. Results: Forty-two subjects with a median age of 6.8 years (Interquartile Range-IQR 4.5, 9.8) were enrolled. A total of 92% were referred with snoring or symptoms of Obstructive Sleep Apnoea (OSA), with 79% of those referred having had previous ENT surgery. Thus, 85% of all participants underwent a sleep study and 61% were diagnosed with OSA (OAHI ≥ 1/h). Based on questionnaires, 86% of respondents indicated that their child had a significant sleep disorder and non-respiratory sleep problems were common. Non-respiratory problems included: trouble going to sleep independently (45%), restless sleep (76%), night-time waking (24%) and bedtime resistance (22%). No significant correlations were found between sleep measures (behavioural and medical sleep problems) and the behavioural, functional or cognitive parameters. Conclusion: Sleep disorders were very common, especially non-respiratory sleep problems. OSA was common despite previous surgery. No association was found between sleep-related problems (snoring, sleep-study-confirmed OSA or non-respiratory sleep problem) and parent-reported behavioural problems, functional impairments or intellectual performance. This may reflect limitations of the measures used in this study, that in this population ongoing problems with daytime function are not sleep related or that a cross-sectional assessment does not adequately take into account the impacts of past disease/treatments. Further research is required to further evaluate the tools used to evaluate sleep disorders, the impact of those disorder on children with Down syndrome and interventions which improve both sleep and daytime function.

scholarly journals High Prevalence of Sleep Disorders and Associated Comorbidities in a Community Sample of Children with Down Syndrome

2014 ◽  
Vol 10 (04) ◽  
pp. 411-419 ◽  
Author(s):  
Claire A. Hoffmire ◽  
Caroline I. Magyar ◽  
Heidi V. Connolly ◽  
I. Diana Fernandez ◽  
Edwin van Wijngaarden
Keyword(s):  
Down Syndrome ◽  
Sleep Disorders ◽  
Community Sample ◽  
Children With Down Syndrome ◽  
High Prevalence
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