Utility of SOX11 for the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas on Cytological Preparations

Cytopathology ◽  
2021 ◽  
Author(s):  
Peyman Dinarvand ◽  
Wei‐Lien Wang ◽  
Sinchita Roy‐Chowdhuri
Keyword(s):  
Solid Pseudopapillary Neoplasm

scholarly journals Solid-pseudopapillary neoplasm of the pancreas in a patient with familial adenomatous polyposis: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daishi Naoi ◽  
Koji Koinuma ◽  
Hideki Sasanuma ◽  
Yasunaru Sakuma ◽  
Hisanaga Horie ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Pancreatic Tumor ◽  
Laparoscopic Resection ◽  
Tumor Development ◽  
Colonic Polyps ◽  
Pancreatic Tumors ◽  
Beta Catenin ◽  
Adenomatous Polyposis ◽  
Solid Pseudopapillary Neoplasm ◽  
Extracolonic Manifestations

Abstract Background Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of colonic polyps, and extracolonic manifestations are likely to occur. Pancreatic tumors are rare extracolonic manifestations in patients with FAP, among which solid-pseudopapillary neoplasm (SPN) are extremely rare. We report here a patient with an SPN of the pancreas found during the follow-up of FAP. Case presentation A 20-year-old woman was diagnosed with FAP 3 years previously by colonoscopy which revealed less than 100 colonic polyps within the entire colon. She complained of left upper abdominal pain and a 10-cm solid and cystic pancreatic tumor was found by computed tomography scan. Solid and cystic components within the tumor were seen on abdominal magnetic resonance imaging. Simultaneous laparoscopic resection of the distal pancreas and subtotal colectomy was performed. Histopathological findings confirmed the pancreatic tumor as an SPN without malignancy. Abnormal staining of beta-catenin was observed by immunohistochemical study. Multiple polyps in the colorectum were not malignant. Molecular biological analysis from peripheral blood samples revealed a decrease in the copy number of the promoter 1A and 1B region of the APC gene, which resulted in decreased expression of the APC gene. Conclusions A rare association of SPN with FAP is reported. The genetic background with relation to beta-catenin abnormalities is interesting to consider tumor development. So far, there are few reports of SPN in a patient with FAP. Both lesions were treated simultaneously by laparoscopic resection.

scholarly journals A case of repeat hepatectomy for liver metastasis from solid pseudopapillary neoplasm of the pancreas: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Atsushi Morito ◽  
Kojiro Eto ◽  
Kozue Matsuishi ◽  
Hirokazu Hamasaki ◽  
Keisuke Morita ◽  
...  
Keyword(s):  
Liver Metastasis ◽  
Liver Metastases ◽  
Distal Pancreatectomy ◽  
Treatment Guidelines ◽  
Histopathological Examination ◽  
Repeat Hepatectomy ◽  
R0 Resection ◽  
Solid Pseudopapillary Neoplasm ◽  
Long Term Prognosis

Abstract Background Solid pseudopapillary neoplasm of the pancreas is a rare tumor in young women, metastasizing in only 5–15% of cases, and most commonly to the liver. Although treatment guidelines have not been established, surgical resection is usually performed. We report a rare case of repeat hepatectomy for liver metastases after distal pancreatectomy with solid pseudopapillary neoplasm. Case presentation The patient was a 71-year-old woman who underwent distal pancreatectomy for solid pseudopapillary neoplasm, and liver metastasis occurred 4 years after the first surgery. Partial liver resection was performed for four liver metastases, and histopathological examination revealed a diagnosis of liver metastasis from solid pseudopapillary neoplasm. However, 18 months later, liver metastases were detected again; three tumors were identified, and partial resection was performed, which has provided 18 months’ recurrence-free survival. Conclusions Long-term prognosis can be expected following R0 resection for resectable liver metastasis from solid pseudopapillary neoplasm.

Solid pseudopapillary neoplasm of the pancreas: distinct patterns of onset, diagnosis, and prognosis for male versus female patients

Surgery ◽  
2008 ◽  
Vol 143 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Marcel C.C. Machado ◽  
Marcel Autran C. Machado ◽  
Telesforo Bacchella ◽  
José Jukemura ◽  
José L. Almeida ◽  
...  
Keyword(s):  
Solid Pseudopapillary Neoplasm ◽  
Female Patients ◽  
Diagnosis And Prognosis

Atypical cytological features of a solid pseudopapillary neoplasm of the pancreas metastatic to the liver

Cytopathology ◽  
2015 ◽  
Vol 27 (3) ◽  
pp. 218-220
Author(s):  
A. Kakkar ◽  
D. Jain ◽  
S. R. Mathur ◽  
V. K. Iyer ◽  
C. Sarkar ◽  
...  
Keyword(s):  
Solid Pseudopapillary Neoplasm ◽  
Cytological Features

A resected case of solid pseudopapillary neoplasm of the pancreas complicated with familial adenomatous polyposis

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S138
Author(s):  
Yuko Suzuki ◽  
Kenji Takahashi ◽  
Hidetaka Iwamoto ◽  
Keisuke Yamakita ◽  
Yohei Kitano ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Solid Pseudopapillary Neoplasm ◽  
Resected Case

Successful laparoscopic distal pancreatectomy for a large solid pseudopapillary neoplasm: A case report

2017 ◽  
Vol 10 (3) ◽  
pp. 317-320 ◽  
Author(s):  
Seiichiro Tada ◽  
Taku Iida ◽  
Takayuki Anazawa ◽  
Shintaro Yagi ◽  
Satoru Seo ◽  
...  
Keyword(s):  
Case Report ◽  
Distal Pancreatectomy ◽  
Laparoscopic Distal Pancreatectomy ◽  
Solid Pseudopapillary Neoplasm

scholarly journals Solid pseudopapillary neoplasm of the head of the pancreas: A case report

2021 ◽  
Vol 69 ◽  
pp. 102708
Author(s):  
Driss Erguibi ◽  
Yassine El Berni ◽  
Aziz Moufakkir ◽  
Rachid Boufettal ◽  
Rifki jai saad ◽  
...  
Keyword(s):  
Case Report ◽  
Solid Pseudopapillary Neoplasm ◽  
Head Of The Pancreas

The prognosis and clinical characteristics of advanced (malignant) solid pseudopapillary neoplasm of the pancreas

Tumor Biology ◽  
2015 ◽  
Vol 37 (4) ◽  
pp. 5347-5353 ◽  
Author(s):  
Hongkai Zhang ◽  
Wenze Wang ◽  
Shuangni Yu ◽  
Yu Xiao ◽  
Jie Chen
Keyword(s):  
Clinical Characteristics ◽  
Solid Pseudopapillary Neoplasm
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