Laparoscopic Resection of a Giant Solid Pseudopapillary Neoplasm of Uncinate Process of the Pancreas in a Child

2011 ◽  
Vol 21 (10) ◽  
pp. 979-982 ◽  
Author(s):  
Feng-Ji Tsai ◽  
Jui-Ying Lee ◽  
Yu-Tang Chang
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daishi Naoi ◽  
Koji Koinuma ◽  
Hideki Sasanuma ◽  
Yasunaru Sakuma ◽  
Hisanaga Horie ◽  
...  

Abstract Background Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of colonic polyps, and extracolonic manifestations are likely to occur. Pancreatic tumors are rare extracolonic manifestations in patients with FAP, among which solid-pseudopapillary neoplasm (SPN) are extremely rare. We report here a patient with an SPN of the pancreas found during the follow-up of FAP. Case presentation A 20-year-old woman was diagnosed with FAP 3 years previously by colonoscopy which revealed less than 100 colonic polyps within the entire colon. She complained of left upper abdominal pain and a 10-cm solid and cystic pancreatic tumor was found by computed tomography scan. Solid and cystic components within the tumor were seen on abdominal magnetic resonance imaging. Simultaneous laparoscopic resection of the distal pancreas and subtotal colectomy was performed. Histopathological findings confirmed the pancreatic tumor as an SPN without malignancy. Abnormal staining of beta-catenin was observed by immunohistochemical study. Multiple polyps in the colorectum were not malignant. Molecular biological analysis from peripheral blood samples revealed a decrease in the copy number of the promoter 1A and 1B region of the APC gene, which resulted in decreased expression of the APC gene. Conclusions A rare association of SPN with FAP is reported. The genetic background with relation to beta-catenin abnormalities is interesting to consider tumor development. So far, there are few reports of SPN in a patient with FAP. Both lesions were treated simultaneously by laparoscopic resection.


HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S709
Author(s):  
M.A. Machado ◽  
R. Surjan ◽  
T. Basseres ◽  
F. Makdissi

2011 ◽  
Vol 25 (10) ◽  
pp. 3426-3427 ◽  
Author(s):  
Fernando Rotellar ◽  
Fernando Pardo ◽  
Alberto Benito ◽  
Pablo Martí-Cruchaga ◽  
Gabriel Zozaya ◽  
...  

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S709-S710
Author(s):  
I. Poves ◽  
O. Morató ◽  
F. Burdío ◽  
L. Grande

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S934
Author(s):  
M.A. Machado ◽  
R. Surjan ◽  
T. Basseres ◽  
F. Makdissi

Cureus ◽  
2021 ◽  
Author(s):  
Muhammad Rafay Khan Niazi ◽  
Samyak Dhruv ◽  
Abhishek Polavarapu ◽  
Mesut Toprak ◽  
Indraneil Mukherjee

HPB ◽  
2017 ◽  
Vol 19 ◽  
pp. S111
Author(s):  
F. Makdissi ◽  
T. Basseres ◽  
R. Surjan ◽  
M.A. Machado

2021 ◽  
Author(s):  
Rohit Bhatta ◽  
Santosh Irrinki ◽  
Vikas Gupta ◽  
Thakur Deen Yadav ◽  
Yashwant Raj Sakaray ◽  
...  

Abstract Background:Solid Pseudopapillary neoplasm (SPN) is uncommon and constitutes to 1-2% of pancreatic tumors. Owing to its rarity, literature is spare on its clinicopathological characteristics and surgical outcomes.MethodsOur study is a retrospective analysis of prospectively maintained data of patients with histologically proven SPN between January,2012 and December,2019. Patients Demography, clinical presentation, preoperative imaging, operative details, perioperative outcomes and long term follow up were recorded and analyzed. ResultsA total of 14 patients were included in the study, all were females with a median age of 19.5 years (range 15 - 35 years). All presented with pain abdomen. Eight (57.1%) out of 14 patients were correctly diagnosed with Contrast enhanced computed tomography (CECT) abdomen. CECT revealed sloid cystic well encapsulated lesions in 12(85.7%) and homogenous mass lesions without cystic changes in 2(14.2%) patients. The most common tumor location was Head/uncinate process (57.1%). Eight (57.1%) underwent pancreaticoduodenectomy and 6 (42.8%) had undergone distal pancreatectomy. The mean size of tumour was 9.5cm(2.8-14cm). The median postoperative stay was 9 days(range 4-20 days). Seven patients (50%) developed post-operative pancreatic fistula (Grade-A-6/7,Grade-B-1/7) and delayed gastric emptying (DGE) were noted in two (14.2%).R0 resection could be achieved in 13 patients (92.8%). Median follow up period was 49.5 months. One patient had postoperative recurrence after 48 months of surgery.ConclusionSPN is a rare tumor of pancreas. Lack of preoperative predictors for malignant potential complete oncological resections is essential for potential cure.


2009 ◽  
Vol 23 (6) ◽  
pp. 1391-1392 ◽  
Author(s):  
M. A. Machado ◽  
F. F. Makdissi ◽  
R. C. Surjan ◽  
M. C. Machado

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e361
Author(s):  
R. Jureidini ◽  
T. Bacchella ◽  
T.C. Ribeiro ◽  
G.N. Namur ◽  
A.C.B. Dantas ◽  
...  

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