Abstract
Background:Solid Pseudopapillary neoplasm (SPN) is uncommon and constitutes to 1-2% of pancreatic tumors. Owing to its rarity, literature is spare on its clinicopathological characteristics and surgical outcomes.MethodsOur study is a retrospective analysis of prospectively maintained data of patients with histologically proven SPN between January,2012 and December,2019. Patients Demography, clinical presentation, preoperative imaging, operative details, perioperative outcomes and long term follow up were recorded and analyzed. ResultsA total of 14 patients were included in the study, all were females with a median age of 19.5 years (range 15 - 35 years). All presented with pain abdomen. Eight (57.1%) out of 14 patients were correctly diagnosed with Contrast enhanced computed tomography (CECT) abdomen. CECT revealed sloid cystic well encapsulated lesions in 12(85.7%) and homogenous mass lesions without cystic changes in 2(14.2%) patients. The most common tumor location was Head/uncinate process (57.1%). Eight (57.1%) underwent pancreaticoduodenectomy and 6 (42.8%) had undergone distal pancreatectomy. The mean size of tumour was 9.5cm(2.8-14cm). The median postoperative stay was 9 days(range 4-20 days). Seven patients (50%) developed post-operative pancreatic fistula (Grade-A-6/7,Grade-B-1/7) and delayed gastric emptying (DGE) were noted in two (14.2%).R0 resection could be achieved in 13 patients (92.8%). Median follow up period was 49.5 months. One patient had postoperative recurrence after 48 months of surgery.ConclusionSPN is a rare tumor of pancreas. Lack of preoperative predictors for malignant potential complete oncological resections is essential for potential cure.