Osteosarcoma mimic in the breast: A recurrent malignant phyllodes tumour harbouring MED12 and hTERT mutations

Cytopathology ◽  
2018 ◽  
Vol 29 (4) ◽  
pp. 383-385
Author(s):  
M. Tokoyoda ◽  
S. Adachi ◽  
Y. Ishida ◽  
K. Yamazaki
Keyword(s):  
Phyllodes Tumour ◽  
Malignant Phyllodes Tumour

scholarly journals Malignant phyllodes tumour presenting as a massive fungating breast mass and silent thrombo-embolism

2015 ◽  
Vol 9 ◽  
pp. 78-81 ◽  
Author(s):  
Anita G. Bourke ◽  
Madeleine McCreanor ◽  
Allen Yeo ◽  
Dieter Weber ◽  
Anthony Bartlett ◽  
...  
Keyword(s):  
Breast Mass ◽  
Phyllodes Tumour ◽  
Malignant Phyllodes Tumour

scholarly journals Acrometastases: The nasty alter ego of fingertip infections

2021 ◽  
Vol 16 (2) ◽  
pp. 86-89
Author(s):  
Collin Seng Kim Looi ◽  
Manohar Arumugam
Keyword(s):  
Primary Care ◽  
Middle Finger ◽  
Distal Phalanx ◽  
Phyllodes Tumour ◽  
Alter Ego ◽  
Left Middle ◽  
Malignant Phyllodes Tumour

Fingertip infections are commonly diagnosed in primary care. There is a serious condition, acrometastases, that is often mistaken for these infections. Acrometastases are defined as metastases located distal to the elbow or knee. We present a case of a malignant phyllodes tumour with acrometastases to the distal phalanx of the left middle finger that was misdiagnosed as a fingertip infection on 2 separate occasions, highlighting the need for vigilance regarding acrometastases.

scholarly journals Giant Malignant Phyllodes Tumour of Breast- A Clinical Dilemma and Surgical Challenge

2021 ◽  
Author(s):  
Raghav Yelamanchi ◽  
Nikhil Gupta ◽  
Dhruv Gupta ◽  
CK Durga
Keyword(s):  
Pectoralis Major Muscle ◽  
Left Breast ◽  
High Index ◽  
Image Guided ◽  
Phyllodes Tumour ◽  
Benign Tumours ◽  
Clinical Dilemma ◽  
Phyllodes Tumours ◽  
High Index Of Suspicion ◽  
Malignant Phyllodes Tumour

Phyllodes tumour is an uncommon tumour of the breast. It is fibroepithelial in origin and mostly benign. Giant phyllodes tumours are described as tumours with size more than 10 cm and are extremely rare. Differentiating malignant and benign tumours pathologically is difficult and needs clinical judgement and high index of suspicion. A 50-year-old female presented with complaint of swelling in the left breast. On further evaluation, it was diagnosed as phyllodes tumour on biopsy. She underwent left mastectomy and excision of pectoralis major muscle due to clinical and radiological suspicion of malignancy. Postoperative histopathology report revealed malignant phyllodes tumour. Cases of giant phyllodes tumour should undergo adequate imaging and image guided biopsy with high index for suspicion for malignancy. They should be operated as per the principles of oncosurgery as there is a high probability of such huge tumours harboring malignancy.

scholarly journals Malignant Phyllodes Tumour with Rhabdomyosarcomatous Differentiation: A Rare Phenomenon

2021 ◽  
Author(s):  
Kusum Yadav ◽  
Jitendra Singh Nigam ◽  
Anshul Singh ◽  
Vatsala Misra
Keyword(s):  
Rare Tumour ◽  
Complete Excision ◽  
Eosinophilic Cytoplasm ◽  
Phyllodes Tumour ◽  
Abundant Eosinophilic Cytoplasm ◽  
One Year ◽  
Phyllodes Tumours ◽  
The Right ◽  
Pleomorphic Cells ◽  
Malignant Phyllodes Tumour

Phyllodes tumour is a rare tumour of the breast constituting less than 1% of all breast tumours. Malignant Phyllodes Tumour (MPT) accounts for only 10-30% of all phyllodes tumours. Heterologous sarcomatous differentiation in a MPT is an infrequent phenomenon, with the cases reported showing differentiation mostly towards liposarcoma, fibrosarcoma, angiosarcoma, osteosarcoma, or chondrosarcoma. MPTs with rhabdomyosarcomatous differentiation are scarcely seen with only three confirmed cases documented till date to the best of the knowledge after a thorough search of literature. Here, authors present a case of 45-year-old female who presented with a well-defined rapidly growing lump in the right breast for last one year. A core needle biopsy performed showed a sarcomatous picture on histology. Complete excision was subsequently done. On microscopy, most of the areas showed fibrosarcomatous changes with frequent mitoses. Some of the foci showed large pleomorphic cells in diffuse sheets that were polygonal with densely abundant eosinophilic cytoplasm and vesicular nucleus with prominent nucleoli (rhabdomyoblasts). Myogenin was diffusely positive on Immunohistochemistry (IHC). A diagnosis of MPT with rhabdomyosarcomatous differentiation was made. This case is reported here for its unusual presentation and to make pathologists aware of this rare heterologous differentiation of MPT.

Malignant phyllodes tumour with a noninvasive ductal carcinoma component

1998 ◽  
Vol 432 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Rieko Nishimura ◽  
Takahiro Hasebe ◽  
Shigeru Imoto ◽  
K. Mukai
Keyword(s):  
Ductal Carcinoma ◽  
Phyllodes Tumour ◽  
Noninvasive Ductal Carcinoma ◽  
Malignant Phyllodes Tumour
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