Malignant phyllodes tumour with a noninvasive ductal carcinoma component

1998 ◽  
Vol 432 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Rieko Nishimura ◽  
Takahiro Hasebe ◽  
Shigeru Imoto ◽  
K. Mukai
Keyword(s):  
Ductal Carcinoma ◽  
Phyllodes Tumour ◽  
Noninvasive Ductal Carcinoma ◽  
Malignant Phyllodes Tumour

scholarly journals Malignant Phyllodes Tumour with Liposarcomatous Differentiation, Invasive Tubular Carcinoma, and Ductal and Lobular Carcinoma In Situ: Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Mardiana Abdul Aziz ◽  
Frank Sullivan ◽  
Michael J. Kerin ◽  
Grace Callagy
Keyword(s):  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Lobular Carcinoma In Situ ◽  
Tubular Carcinoma ◽  
In Situ Carcinoma ◽  
Phyllodes Tumour ◽  
Radiotherapy Treatment ◽  
Malignant Phyllodes Tumour

A 43-year-old woman presented with a right breast lump that had enlarged over 5 months. She had chemoradiotherapy for non-Hodgkin’s lymphoma in 1989. Histology revealed a malignant phyllodes tumour (PT) with liposarcomatous differentiation and ductal carcinoma in situ (DCIS) within the tumour with invasive tubular carcinoma, DCIS, and lobular carcinoma in situ in the surrounding breast. She had surgery and adjuvant radiotherapy. One year follow-up showed no recurrence or metastatic disease. Liposarcomatous differentiation is uncommon in PTs, and coexisting carcinoma is rare with 38 cases in 31 reports in the literature. Carcinoma is reported in malignant (), benign () and in borderline PTs () with invasive carcinoma () and pure in situ carcinoma () recorded in equal frequency. Carcinoma is more commonly found within the confines of benign PTs; whereas it is more often found surrounding the PT or in the contralateral breast in malignant PTs. Previous radiotherapy treatment is reported in only two cases. The aetiology of co-existing carcinoma is unclear but the rarity of previous radiotherapy treatment suggests that it is incidental. This case highlights the diverse pathology that can occur with PTs, which should be considered when evaluating pathology specimens as they may impact on patient management.

Infiltrating ductal carcinoma and synchronous malignant phyllodes tumour: Diagnostic and therapeutic approaches

2006 ◽  
Vol 8 (11) ◽  
pp. 830-832 ◽  
Author(s):  
Belén Merck ◽  
Pilar Cansado Martínez ◽  
Miguel Pérez Ramos ◽  
Natividad Martínez Banaclocha ◽  
Francisco Javier Lacueva Gómez ◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Therapeutic Approaches ◽  
Infiltrating Ductal Carcinoma ◽  
Phyllodes Tumour ◽  
Malignant Phyllodes Tumour

scholarly journals High-grade ductal carcinoma in-situ detected by microcalcification within borderline phyllodes tumour: A report of a case and literature review

2021 ◽  
Author(s):  
Wing Nam Yuen ◽  
Joshua Jing Xi Li ◽  
Man Yi Chan ◽  
Gary M Tse
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Surgical Excision ◽  
Management Plan ◽  
High Grade ◽  
Total Mastectomy ◽  
Phyllodes Tumour ◽  
Phyllodes Tumours

Abstract BackgroundPhyllodes tumour is a rare biphasic neoplasm of the breast that mostly affects middle aged women. Ductal carcinoma in-situ and microcalcifications occurring within phyllodes tumours are documented but are rare findings. Primary surgical excision with adjuvant therapies remains the mainstay of treatment.Case presentationWe report a case of a 42-year-old woman with high-grade ductal carcinoma in-situ within a borderline phyllodes tumour. Radiologically, clumps of microcalcification were detected within the lesion. Local excision followed by total mastectomy with axillary dissection was then performed. No tumour recurrence was detected up to a period of 8 years.ConclusionPresence of microcalcifications within a phyllodes tumour should alert clinicians and pathologists of possible coexisting carcinoma components. Stromal and epithelial components of these lesions should be evaluated separately when formulating a management plan.

Breast pathology

2017 ◽  
Author(s):  
James Carton
Keyword(s):  
Ductal Carcinoma ◽  
Breast Diseases ◽  
Radial Scar ◽  
Granulomatous Mastitis ◽  
Breast Carcinomas ◽  
Breast Pathology ◽  
Fibrocystic Change ◽  
Phyllodes Tumour ◽  
Invasive Breast Carcinomas

This chapter discusses breast pathology, including duct ectasia, granulomatous mastitis, fat necrosis, fibrocystic change, fibroadenoma, phyllodes tumour, intraductal papilloma, radial scar, proliferative breast diseases with and without atypia, ductal carcinoma in situ (DCIS), invasive breast carcinomas, breast screening, and male breast diseases.

scholarly journals Ductal carcinoma in-situ arising within benign phyllodes tumours

2018 ◽  
Vol 100 (4) ◽  
pp. e97-e102 ◽  
Author(s):  
S-A Lui ◽  
HB Oh ◽  
S Wang ◽  
CW Chan
Keyword(s):  
Ductal Carcinoma In Situ ◽  
Wide Local Excision ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Review Of The Literature ◽  
Breast Lump ◽  
Final Histology ◽  
Phyllodes Tumour ◽  
Phyllodes Tumours

Ductal carcinoma in situ arising within a benign phyllodes tumour is a rare neoplasm of the breast. We present a case of a 19-year-old woman who had a right breast lump for six months with the above diagnosis together with a mini-review of the literature. Ultrasound revealed a 5-cm breast lump and core biopsy revealed ductal carcinoma in situ. She underwent wide local excision of the breast lump with clear margins. Final histology confirmed ductal carcinoma in situ within a fibroepithelial lesion consistent with a benign phyllodes tumour. To our knowledge, this is the youngest case of ductal carcinoma in situ arising in a phyllodes tumour to have been reported so far.

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