scholarly journals Mast cell phenotypes in the allograft after lung transplantation

2016 ◽  
Vol 30 (7) ◽  
pp. 845-851 ◽  
Author(s):  
Amit Banga ◽  
Yingchun Han ◽  
Xiaofeng Wang ◽  
Fred H. Hsieh
Keyword(s):  
Mast Cell ◽  
Lung Transplantation ◽  
Cell Phenotypes

Phenotypic and Quantitative Changes in Mast Cells after Syngeneic Unilateral Lung Transplantation in the Rat

1996 ◽  
Vol 91 (3) ◽  
pp. 319-327 ◽  
Author(s):  
Annick Buvry ◽  
Monique Garbarg ◽  
Violetta Dimitriadou ◽  
Agnès Rouleau ◽  
George F. J. Newlands ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Lung Transplantation ◽  
Left Lung ◽  
Muscle Layer ◽  
Rat Lung ◽  
Large Airways ◽  
Quantitative Changes ◽  
Cell Phenotypes ◽  
And Control

1. Lung transplantation causes a total interruption of the innervation and vascularization within the transplanted organ, followed by repair processes. This is frequently associated with bronchial hyper-responsiveness. A common feature of tissue repair is an increase in the number of mast cells. Three phenotypically distinct mast cell subsets, with respect to their protease content, have been identified in rat lung, and it is probable that mast cells of differing protease phenotype fulfil different functions. 2. We have compared the number, protease phenotype and distribution of mast cells in left lung from transplanted and control Lewis rats 1 month after syngeneic unilateral left lung transplantation, without interference of inflammation, graft rejection or of any treatment. Connective and mucosal-type mast cell phenotypes were characterized using antibodies directed against their specific rat mast cell proteases, RMCPI and RMCPII, respectively. 3. After transplantation, RMCPI and RMCPII tissue concentrations increased by 172% and 239%, respectively, compared with controls (13.1 ± 1.2 and 5.6±1.0 μg/g). 4. Localization of mast cell phenotypes was studied by immunohistochemistry after double immunostaining. The number of mast cells increased after transplantation: the increase in the number of RMCPI-immunoreactive mast cells (RMCPI+) was significant around bronchioles and arterioles, around large vessels and in the pleura. The number of RMCPII+ mast cells also significantly increased around bronchioles and arterioles, as well as in the smooth muscle layer of large airways. Some mast cells stained for the presence of both RMCPI and RMCPII, supporting the existence of co-expressing phenotype in rat lung. The number of mast cells of the RMCPI+ /H+ phenotype significantly increased around bronchioles and arterioles and in the pleura. Moreover, the distribution of the mast cell phenotypes was modified in the different areas after transplantation. 5. This indicates a local differentiation/maturation of mast cells after transplantation.

Mast Cell Phenotypes in the Allograft After Lung Transplantation.

2015 ◽  
Vol 34 (4) ◽  
pp. S261 ◽  
Author(s):  
A. Banga ◽  
M.M. Budev ◽  
X. Wang ◽  
F. Hsieh
Keyword(s):  
Mast Cell ◽  
Lung Transplantation ◽  
Cell Phenotypes

scholarly journals Skin mast cell phenotypes between two highly divergent cohorts - more pronounced variability within than between groups

2017 ◽  
Vol 26 (5) ◽  
pp. 446-449 ◽  
Author(s):  
Magda Babina ◽  
Sven Guhl ◽  
Metin Artuc ◽  
Torsten Zuberbier
Keyword(s):  
Mast Cell ◽  
Skin Mast Cell ◽  
Cell Phenotypes

Mast cell phenotypes and microvessels in non–small cell lung cancer and its prognostic significance

2010 ◽  
Vol 41 (5) ◽  
pp. 697-705 ◽  
Author(s):  
María José Carlini ◽  
Mercedes Corina Liliana Dalurzo ◽  
José María Lastiri ◽  
David Eduardo Smith ◽  
Bartolomé Carlos Vasallo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Mast Cell ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Small Cell ◽  
Small Cell Lung ◽  
Cell Phenotypes

scholarly journals Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes

2020 ◽  
Author(s):  
Heidi Hempel Sullivan ◽  
Janielle P. Maynard ◽  
Christopher M. Heaphy ◽  
Jiayun Lu ◽  
Angelo M. De Marzo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Mast Cell ◽  
Oncologic Outcomes ◽  
Cancer Tissues ◽  
Cell Phenotypes

scholarly journals Mast cell phenotypes in human transplanted kidneys

1998 ◽  
Vol 76 ◽  
pp. 70
Author(s):  
M Yamada ◽  
M Ueda ◽  
T Naruko ◽  
S Tanabe ◽  
S Takai ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Phenotypes ◽  
Transplanted Kidneys

Temporal distribution of distinct mast cell phenotypes during intestinal schistosomiasis in mice

2002 ◽  
Vol 24 (5) ◽  
pp. 225-231 ◽  
Author(s):  
Frederik De Jonge ◽  
Luc Van Nassauw ◽  
Frans Van Meir ◽  
Hugh R. P. Miller ◽  
Eric Van Marck ◽  
...  
Keyword(s):  
Mast Cell ◽  
Temporal Distribution ◽  
Intestinal Schistosomiasis ◽  
Cell Phenotypes

Mast Cell Phenotypes and Distribution in Nasal Polyps with Allergic Airway

2012 ◽  
Vol 129 (2) ◽  
pp. AB120
Author(s):  
E.E. Fouda ◽  
S. Abdelgawad ◽  
S. Said-Ahmed ◽  
A. Ali ◽  
E. Mohamed
Keyword(s):  
Mast Cell ◽  
Nasal Polyps ◽  
Cell Phenotypes
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