Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone

2014 ◽  
Vol 28 (7) ◽  
pp. 762-767 ◽  
Author(s):  
Kristi J. Beermann ◽  
Matthew J. Ellis ◽  
Debra L. Sudan ◽  
Matthew T. Harris
Keyword(s):  
African American ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Tacrolimus Dose

scholarly journals P1706THE GRAFT SURVIVAL OF KIDNEY TRANSPLANTATION ACCORDING TO ETHNICITY IN KIDNEY TRANSPLANT RECIPIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Yeonsoon Jung ◽  
Jisu Kim ◽  
Haesu Jeon ◽  
Ye Na Kim ◽  
Ho Sik Shin ◽  
...  
Keyword(s):  
African American ◽  
Kidney Transplantation ◽  
Kidney Transplant ◽  
Graft Survival ◽  
Cox Regression ◽  
Patient Survival ◽  
Graft Loss ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Data Set

Abstract Background African American kidney transplant recipients experience disproportionately high rates of graft loss. The aim of this analysis was to use a UNOS data set that contains detailed baseline and longitudinal clinical data to establish and quantify the impact of the current overall graft loss definition on suppressing the true disparity magnitude in US AA kidney transplant outcomes. Methods Longitudinal cohort study of kidney transplant recipients using a data set created by United Network for Organ Sharing (UNOS), including 266,128 (African American 70,215, Non-African American 195,913) transplant patient between 1987 and December 2016. Multivariable analysis was conducted using 2-stage joint modeling of random and fixed effects of longitudinal data (linear mixed model) with time to event outcomes (Cox regression). Results 195,913 non-African American (AA) (73.6%) were compared with 70,215 AA (26.4%) recipients. 10-year-graft survival of AA in all era is lower than that of non-AA (31% in deceased kidney transplants (DKT) AA recipient and 42% in living kidney transplantation (LKT) non-AA recipient). 10-year-patient survival of AA with functioning graft in all era is similar that of non-AA. Multivariate Cox regression of factors associated with patient survival with functioning graft are acute rejection within 6 months, DM, hypertension and etc. Pre-transplant recipient BMI in AA show the trend as a protective factor in patient survival with functioning graft although not significantly in statistics Conclusions African American kidney transplant recipients experience a substantial disparity in graft loss, but not patient death with functioning graft.

Pretransplant Tacrolimus Dose Requirements Predict Early Posttransplant Dose Requirements in Blood Group AB0-Incompatible Kidney Transplant Recipients

2016 ◽  
Vol 38 (2) ◽  
pp. 217-222 ◽  
Author(s):  
Nauras Shuker ◽  
Femke M. de Man ◽  
Annelies E. de Weerd ◽  
Madelon van Agteren ◽  
Willem Weimar ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Blood Group ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Tacrolimus Dose

Induction Therapy with Basiliximab versus Thymoglobulin in African-American Kidney Transplant Recipients

2005 ◽  
Vol 79 (6) ◽  
pp. 716-721 ◽  
Author(s):  
Abdolreza Haririan ◽  
Katherina Morawski ◽  
Dale H. Sillix ◽  
Jose M. El-Amm ◽  
James Garnick ◽  
...  
Keyword(s):  
African American ◽  
Kidney Transplant ◽  
Induction Therapy ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

scholarly journals Genotype-guided tacrolimus dosing in African-American kidney transplant recipients

2015 ◽  
Vol 17 (1) ◽  
pp. 61-68 ◽  
Author(s):  
K Sanghavi ◽  
◽  
R C Brundage ◽  
M B Miller ◽  
D P Schladt ◽  
...  
Keyword(s):  
African American ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

Impact of CYP3A5 genomic variances on clinical outcomes among African American kidney transplant recipients

2017 ◽  
Vol 32 (1) ◽  
pp. e13162 ◽  
Author(s):  
Tomefa E. Asempa ◽  
Lorita M. Rebellato ◽  
Suzanne Hudson ◽  
Kimberly Briley ◽  
Angela Q. Maldonado
Keyword(s):  
African American ◽  
Clinical Outcomes ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients
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