scholarly journals Promyelocytic leukaemia zinc finger maintains self‐renewal of male germline stem cells ( mGSC s) and its expression pattern in dairy goat testis

2013 ◽  
Vol 46 (4) ◽  
pp. 457-468 ◽  
Author(s):  
W. Song ◽  
H. Zhu ◽  
M. Li ◽  
N. Li ◽  
J. Wu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Expression Pattern ◽  
Zinc Finger ◽  
Promyelocytic Leukaemia ◽  
Dairy Goat ◽  
Germline Stem Cells ◽  
Self Renewal ◽  
Male Germline ◽  
Male Germline Stem Cells

Expression pattern of Boule in dairy goat testis and its function in promoting the meiosis in male germline stem cells (mGSCs)

2012 ◽  
Vol 114 (2) ◽  
pp. 294-302 ◽  
Author(s):  
Mingzhao Li ◽  
Chao Liu ◽  
Haijing Zhu ◽  
Junwei Sun ◽  
Meng Yu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Expression Pattern ◽  
Dairy Goat ◽  
Germline Stem Cells ◽  
Male Germline ◽  
Male Germline Stem Cells

Functions of promyelocytic leukaemia zinc finger (Plzf) in male germline stem cell development and differentiation

2019 ◽  
Vol 31 (8) ◽  
pp. 1315 ◽  
Author(s):  
Daguia Zambe John Clotaire ◽  
Yudong Wei ◽  
Xiuwei Yu ◽  
Tamgue Ousman ◽  
Jinlian Hua
Keyword(s):  
Stem Cells ◽  
Zinc Finger ◽  
Zinc Finger Protein ◽  
Development Stage ◽  
Cell Development ◽  
Promyelocytic Leukaemia ◽  
Germline Stem Cell ◽  
Germline Stem Cells ◽  
Male Germline ◽  
Finger Protein

Promyelocytic leukaemia zinc finger (Plzf), also known as zinc finger and BTB domain containing 16 (ZBTB16) or zinc-finger protein 145 (ZFP145), is a critical zinc finger protein of male germline stem cells (mGSCs). Multiple lines of evidence indicate that Plzf has a central role in the development, differentiation and maintenance of many stem cells, including mGSCs, and Plzf has been validated as an essential transcription factor for mammalian testis development and spermatogenesis. This review summarises current literature focusing on the significance of Plzf in maintaining and regulating self-renewal and differentiation of mGSCs, especially goat mGSCs. The review summarises evidence of the specificity of Plzf expression in germ cell development stage, the known functions of Plzf and the microRNA-mediated mechanisms that control Plzf expression in mGSCs.

scholarly journals Functional Assessment of Self-Renewal Activity of Male Germline Stem Cells Following Cytotoxic Damage and Serial Transplantation1

2003 ◽  
Vol 68 (5) ◽  
pp. 1801-1807 ◽  
Author(s):  
Mito Kanatsu-Shinohara ◽  
Shinya Toyokuni ◽  
Takeshi Morimoto ◽  
Shigeyuki Matsui ◽  
Tasuku Honjo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Functional Assessment ◽  
Germline Stem Cells ◽  
Self Renewal ◽  
Male Germline ◽  
Male Germline Stem Cells

scholarly journals Centrosome misorientation mediates slowing of the cell cycle under limited nutrient conditions in Drosophila male germline stem cells

2012 ◽  
Vol 23 (8) ◽  
pp. 1524-1532 ◽  
Author(s):  
Therese M. Roth ◽  
C.-Y. Ason Chiang ◽  
Mayu Inaba ◽  
Hebao Yuan ◽  
Viktoria Salzmann ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Stem Cells ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Germline Stem Cells ◽  
Self Renewal ◽  
Stem Cell Regulation ◽  
Male Germline ◽  
Male Germline Stem Cells ◽  
Nutrient Conditions

Drosophila male germline stem cells (GSCs) divide asymmetrically, balancing self-renewal and differentiation. Although asymmetric stem cell division balances between self-renewal and differentiation, it does not dictate how frequently differentiating cells must be produced. In male GSCs, asymmetric GSC division is achieved by stereotyped positioning of the centrosome with respect to the stem cell niche. Recently we showed that the centrosome orientation checkpoint monitors the correct centrosome orientation to ensure an asymmetric outcome of the GSC division. When GSC centrosomes are not correctly oriented with respect to the niche, GSC cell cycle is arrested/delayed until the correct centrosome orientation is reacquired. Here we show that induction of centrosome misorientation upon culture in poor nutrient conditions mediates slowing of GSC cell proliferation via activation of the centrosome orientation checkpoint. Consistently, inactivation of the centrosome orientation checkpoint leads to lack of cell cycle slowdown even under poor nutrient conditions. We propose that centrosome misorientation serves as a mediator that transduces nutrient information into stem cell proliferation, providing a previously unappreciated mechanism of stem cell regulation in response to nutrient conditions.

Retinol (vitamin A) maintains self-renewal of pluripotent male germline stem cells (mGSCs) from adult mouse testis

2011 ◽  
Vol 112 (4) ◽  
pp. 1009-1021 ◽  
Author(s):  
Shanshan Zhang ◽  
Junwei Sun ◽  
Shaohui Pan ◽  
Haijing Zhu ◽  
Long Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Vitamin A ◽  
Adult Mouse ◽  
Mouse Testis ◽  
Germline Stem Cells ◽  
Self Renewal ◽  
Male Germline ◽  
Male Germline Stem Cells

LIN28A activates the transcription of NANOG in dairy goat male germline stem cells

2018 ◽  
Vol 234 (6) ◽  
pp. 8113-8121 ◽  
Author(s):  
Fanglin Ma ◽  
Xiaomin Du ◽  
Yudong Wei ◽  
Zhe Zhou ◽  
Daguia Zambe John Clotaire ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dairy Goat ◽  
Germline Stem Cells ◽  
Male Germline ◽  
Male Germline Stem Cells

The function of Msx1 gene in promoting meiosis of dairy goat male germline stem cells (mGSCs)

2013 ◽  
Vol 31 (8) ◽  
pp. 629-635 ◽  
Author(s):  
Hailong Mu ◽  
Jiang Wu ◽  
Haijing Zhu ◽  
Na Li ◽  
Furong Tang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dairy Goat ◽  
Germline Stem Cells ◽  
Male Germline ◽  
Male Germline Stem Cells
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