Restorative proctocolectomy for ulcerative colitis: development and validation of a new scoring system for pouch dysfunction and quality of life

2013 ◽  
Vol 15 (12) ◽  
pp. e719-e725 ◽  
Author(s):  
S. Brandsborg ◽  
R. J. Nicholls ◽  
L. S. Mortensen ◽  
S. Laurberg
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Ola Røkke ◽  
Knut Iversen ◽  
Torill Olsen ◽  
Sølvi-May Ristesund ◽  
Geir Egil Eide ◽  
...  

Objective. Study the functional results and mucosal changes in the ileal pouch after restorative proctocolectomy with J-reservoir for ulcerative colitis. Material and Methods. Followup study of 125 patients with J-reservoir with one disease-specific- and one general (SF-36) quality of life-questionnaire, rectoscopy with biopsies, and stool samples to evaluate inflammation, dysplasia, presence of Helicobacter pylori and calprotectin level. Results. Fourteen J-reservoirs were removed or deactivated, leaving 111 patients for followup. The followup time was 6.8 (1–15) years. 87.4% of the patients were satisfied. 93.1% had some kind of functional restriction: food- (75.5%), social- (28.9%), physical- (37%) or sexual restriction (15.3%). 18.6% had often or sometimes faecal incontinence. Low daytime faecal frequency was associated with good quality of life. 13 patients (12.6%) had a less favourable result. There was no pouch-dysplasia. Calprotectin levels were increased in patients with visible pouch inflammation or history of pouchitis. HP was diagnosed by RUT in 42.3%, but was not associated with inflammation or pouchitis. Conclusions. Most patients were satisfied with the J-reservoir in spite of a high frequency of various restrictions. 12.6% (13 patients) had a less favourable functional result, partly due to a high frequency of defecations, pain, pouchitis and inflammation.


2009 ◽  
Vol 3 (1) ◽  
pp. S36
Author(s):  
S.D. McLaughlin ◽  
S.K. Clark ◽  
Z.L. Perry-Woodford ◽  
P.P. Tekkis ◽  
P.J. Ciclitira ◽  
...  

Clinics ◽  
2009 ◽  
Vol 64 (9) ◽  
pp. 877-883 ◽  
Author(s):  
Alberto Luiz Monteiro Meyer ◽  
Magaly Gêmeo Teixeira ◽  
Maristela Gomes de Almeida ◽  
Desidério Roberto Kiss ◽  
Sergio Carlos Nahas ◽  
...  

2017 ◽  
Vol 32 (9) ◽  
pp. 1812-1818 ◽  
Author(s):  
M. Riiskjær ◽  
A.G. Egekvist ◽  
D. Hartwell ◽  
A. Forman ◽  
M. Seyer-Hansen ◽  
...  

2018 ◽  
Vol 107 (4) ◽  
pp. 315-321 ◽  
Author(s):  
I. Helavirta ◽  
M. Hyöty ◽  
P. Oksanen ◽  
H. Huhtala ◽  
J. Haapamäki ◽  
...  

Background and Aims: Patients undergoing restorative proctocolectomy have often suffered from active ulcerative colitis which should be remembered when assessing quality of life after operation. The aim of this study was to explore health-related quality of life after restorative proctocolectomy in those with poor or good pouch function and to compare that to patients with active or inactive ulcerative colitis and to the general population. Material and Methods: Altogether, 282 restorative proctocolectomy patients were investigated. The control group comprised 408 ulcerative colitis patients from the local register. Generic 15D and disease-specific inflammatory bowel disease questionnaire health-related quality of life instruments were used. Population-based data were available for 15D. Pouch function was evaluated with Öresland score and colitis activity with simple clinical colitis activity index. Results: 15D results showed that patients with good pouch function had health-related quality of life similar to that of the general population. Health-related quality of life with inflammatory bowel disease questionnaire was equally good in patients with good pouch function (n = 131; 70%) and inactive colitis (n = 95; 63%), and equally impaired in patients with poor pouch function (n = 56; 30%) and active colitis (n = 18; 12%). Conclusion: The majority of patients had health-related quality of life comparable to that in general population. Most patients with active ulcerative colitis are likely to improve their health-related quality of life after successful surgery. These findings are important when informing colitis patients about life after surgery.


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