Restorative proctocolectomy in patients with ulcerative colitis: a cross-sectional Danish population study on function and quality of life

2013 ◽  
Vol 15 (8) ◽  
pp. e453-e461 ◽  
Author(s):  
S. Brandsborg ◽  
A. Tøttrup ◽  
J. Nicholls ◽  
S. Laurberg
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Ola Røkke ◽  
Knut Iversen ◽  
Torill Olsen ◽  
Sølvi-May Ristesund ◽  
Geir Egil Eide ◽  
...  

Objective. Study the functional results and mucosal changes in the ileal pouch after restorative proctocolectomy with J-reservoir for ulcerative colitis. Material and Methods. Followup study of 125 patients with J-reservoir with one disease-specific- and one general (SF-36) quality of life-questionnaire, rectoscopy with biopsies, and stool samples to evaluate inflammation, dysplasia, presence of Helicobacter pylori and calprotectin level. Results. Fourteen J-reservoirs were removed or deactivated, leaving 111 patients for followup. The followup time was 6.8 (1–15) years. 87.4% of the patients were satisfied. 93.1% had some kind of functional restriction: food- (75.5%), social- (28.9%), physical- (37%) or sexual restriction (15.3%). 18.6% had often or sometimes faecal incontinence. Low daytime faecal frequency was associated with good quality of life. 13 patients (12.6%) had a less favourable result. There was no pouch-dysplasia. Calprotectin levels were increased in patients with visible pouch inflammation or history of pouchitis. HP was diagnosed by RUT in 42.3%, but was not associated with inflammation or pouchitis. Conclusions. Most patients were satisfied with the J-reservoir in spite of a high frequency of various restrictions. 12.6% (13 patients) had a less favourable functional result, partly due to a high frequency of defecations, pain, pouchitis and inflammation.


2018 ◽  
Vol 50 (2) ◽  
pp. e204
Author(s):  
C. Marinelli ◽  
F. Zingone ◽  
M. Inferrera ◽  
G. Lorenzon ◽  
A. Rigo ◽  
...  

2009 ◽  
Vol 3 (1) ◽  
pp. S36
Author(s):  
S.D. McLaughlin ◽  
S.K. Clark ◽  
Z.L. Perry-Woodford ◽  
P.P. Tekkis ◽  
P.J. Ciclitira ◽  
...  

Clinics ◽  
2009 ◽  
Vol 64 (9) ◽  
pp. 877-883 ◽  
Author(s):  
Alberto Luiz Monteiro Meyer ◽  
Magaly Gêmeo Teixeira ◽  
Maristela Gomes de Almeida ◽  
Desidério Roberto Kiss ◽  
Sergio Carlos Nahas ◽  
...  

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