Contact allergy to haptens in the Swedish baseline series. Results from the Swedish Patch Test Register 2010–2017

2021 ◽  
Author(s):  
Daniel Andernord ◽  
Magnus Bruze ◽  
Ing‐Liss Bryngelsson ◽  
Johanna Bråred Christensson ◽  
Bo Glas ◽  
...  
Keyword(s):  
2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Hai-yan Cheng ◽  
Lin-feng Li

Background. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD. Methods. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered. Results. There were no significant differences in age and sex between ICD and control groups. It was found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value (319.90 ± 70.49 vs 347.93 ± 84.55, P < 0.05, Independent-Samples T test) were much lower in ICD than control group. Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%, P < 0.05, Fisher’s exact test) was significantly higher in ICD group. Conclusions. In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.


2019 ◽  
Vol 81 (2) ◽  
pp. 104-109 ◽  
Author(s):  
Magnus Bruze ◽  
Martin Mowitz ◽  
Robert Ofenloch ◽  
Pieter‐Jan Coenraads ◽  
Thomas L. Diepgen ◽  
...  

2018 ◽  
Vol 25 (4) ◽  
pp. e497-e498 ◽  
Author(s):  
Alin L. Tatu ◽  
Marius A. Ionescu ◽  
Lawrence C. Nwabudike

2015 ◽  
Vol 72 (5) ◽  
pp. 297-304 ◽  
Author(s):  
Sofia Fall ◽  
Magnus Bruze ◽  
Marléne Isaksson ◽  
Carola Lidén ◽  
Mihaly Matura ◽  
...  

2000 ◽  
Vol 43 (2) ◽  
pp. 107-109 ◽  
Author(s):  
Tomaž Lunder ◽  
Aleksej Kansky

2022 ◽  
Vol 1 ◽  
pp. 17-20
Author(s):  
Trupti Desale ◽  
Abhishek De ◽  
S. K. Shahriar Ahmed ◽  
Aarti Sarda ◽  
Kiran Godse ◽  
...  

Objectives: Chronic spontaneous urticaria (CSU) is defined as short lived (< 24h) wheals occurring spontaneously without any triggering factors, daily or almost daily for at least 6 weeks. Though CSU is mainly a Type 1 hypersensitivity reaction, earlier studies suggested contact allergy may have some role to play an important role in the etiopathogenesis of CSU. The objective of the study is to find out the relevance of patch test in the etiopathogenesis of and its correlation with serum IgE level. Materials and Methods: Thirty-one patients of CSU were thoroughly evaluated for clinical and laboratory parameters. We conducted patch testing with Indian Standard Series (ISS) in all of them and tried to find out the relevance of every positive reaction. Relevant positive cases were asked to avoid exposure for 2 months and were maintained only in breakthrough antihistamines. Furthermore, correlation of positive patch test reaction with high IgE and eosinophil count were studied. Results: Seventeen (55%) cases came positive for patch test. Potassium dichromate, lanolin, benzocaine, and fragrance mix were the most common offenders. Patients with very high IgE count had patch test positivity with multiple allergens. Seven of the fifteen patients who had relevant positive patch results could be followed up to remission; three were lost to follow-up. Conclusion: Patch test with ISS may give important clue to in a subset of patients of CSU and thus may be considered an important part of routine investigations of CSU.


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