Can contact allergy top-phenylenediamine explain the high rates of terpene hydroperoxide allergy? - An epidemiological study based on consecutive patch test results

2016 ◽  
Vol 76 (2) ◽  
pp. 67-73 ◽  
Author(s):  
Niels Højsager Bennike ◽  
Jean-Pierre Lepoittevin ◽  
Jeanne D. Johansen
Keyword(s):  
Patch Test ◽  
Epidemiological Study ◽  
Contact Allergy ◽  
Test Results

scholarly journals Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Hai-yan Cheng ◽  
Lin-feng Li
Keyword(s):  
Contact Dermatitis ◽  
Patch Test ◽  
Contact Allergy ◽  
Nickel Sulfate ◽  
Tibetan Medicine ◽  
Control Group ◽  
Irritant Contact Dermatitis ◽  
Test Results ◽  
Biophysical Parameters ◽  
Nickel Allergy

Background. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD. Methods. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered. Results. There were no significant differences in age and sex between ICD and control groups. It was found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value (319.90 ± 70.49 vs 347.93 ± 84.55, P < 0.05, Independent-Samples T test) were much lower in ICD than control group. Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%, P < 0.05, Fisher’s exact test) was significantly higher in ICD group. Conclusions. In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.

Increase in contact allergy to fragrances: patch-test results 1989-1998

2000 ◽  
Vol 43 (2) ◽  
pp. 107-109 ◽  
Author(s):  
Tomaž Lunder ◽  
Aleksej Kansky
Keyword(s):  
Patch Test ◽  
Contact Allergy ◽  
Test Results

scholarly journals Patch Testing in Lao medical students

2019 ◽  
Author(s):  
Catriona I. Wootton ◽  
Mick Soukavong ◽  
Sonexai Kidoikhammouan ◽  
Bounthome Samountry ◽  
John S.C. English ◽  
...  
Keyword(s):  
Medical Students ◽  
Patch Test ◽  
Patch Testing ◽  
Contact Allergy ◽  
Background Level ◽  
Future Research ◽  
Formaldehyde Resin ◽  
Test Results ◽  
Positive Patch Test ◽  
Cobalt Dichloride

AbstractBackgroundDermatological services in Laos, South East Asia are limited to the capital and patch testing is currently not available, so no data exists regarding the common cutaneous allergens in this population.ObjectivesThe aim of this study was to document common allergens in medical students in Laos. Patients/Materials/MethodsOne hundred and fifty medical students were patch tested using TRUE Test® panels 1 to 3 (35 allergens). Readings were taken at Days 2 and 4.ResultsThirty-eight students (25.3%) had a positive reaction to at least one allergen, accounting for 52 reactions in total. The proportion of the students with positive patch test reading was significantly higher in the female [33/96 (34%)] than in the male [5/54 (9%)], p<0.001. The most common allergens were: nickel (10%), gold (6.6%), thiomersal (6.6%), cobalt dichloride (2%) and p-tert-Butylphenol formaldehyde resin (2%). Balsam of Peru (0.66%), black rubber mix (0.66%), Cl+Me-Isothiazolinone (0.66%), fragrance mix 1 (0.66%), quinolone mix (0.66%), methyldibromo glutaronitrile (0.66%), mercapto mix (0.66%), epoxy resin (0.66%), paraben mix (0.66%), thiuram (0.66%) and wool alcohols (0.66%) accounted for all of the other positive reactions.ConclusionThis study represents the first documented patch test results in Lao medical students and in the adult Lao population. The results of this study will inform any future research into contact allergy in Laos and give an insight into the background level of contact sensitivity in this population.

Contact allergy to essential oils: current patch test results (2000-2008) from the Information Network of Departments of Dermatology (IVDK)*

2010 ◽  
Vol 63 (5) ◽  
pp. 277-283 ◽  
Author(s):  
Wolfgang Uter ◽  
Erich Schmidt ◽  
Johannes Geier ◽  
Holger Lessmann ◽  
Axel Schnuch ◽  
...  
Keyword(s):  
Essential Oils ◽  
Patch Test ◽  
Contact Allergy ◽  
Information Network ◽  
Test Results

scholarly journals Current patch test results with the European baseline series and extensions to it from the ‘European Surveillance System on Contact Allergy’ network, 2007-2008

2012 ◽  
Vol 67 (1) ◽  
pp. 9-19 ◽  
Author(s):  
Wolfgang Uter ◽  
Werner Aberer ◽  
José Carlos Armario-Hita ◽  
José M. Fernandez-Vozmediano ◽  
Fabio Ayala ◽  
...  
Keyword(s):  
Patch Test ◽  
Surveillance System ◽  
Contact Allergy ◽  
Test Results

Assessment of Skin Photoallergy Risk in Cosmetics Containing Herbal Extract Ingredients

2021 ◽  
pp. 1-9
Author(s):  
Nannan Pan ◽  
Yue Xia ◽  
Wenyi Hou ◽  
Gouxing Zhu ◽  
Jie Zhang ◽  
...  
Keyword(s):  
Patch Test ◽  
Contact Allergy ◽  
Test System ◽  
Herbal Extract ◽  
Test Results ◽  
Herbal Extracts ◽  
Chlorpromazine Hydrochloride ◽  
Type Iv ◽  
Cosmetic Ingredients ◽  
Chinese Subjects

<b><i>Background/Objective:</i></b> In recent years, herbal extracts are becoming increasingly popular ingredients added in cosmetics; however, the assessment of their potential adverse effects on the skin remains unclear. As <i>Coptis</i>, <i>Phellodendron amurense</i>, curcumin, and shikonin are herbs currently used in cosmetic ingredients, the aim of this study was to assess their skin photoallergy (PA) potential and the concentrations at which they could safely be used. <b><i>Methods:</i></b> In the patch test, <i>Coptis</i>, <i>P. amurense</i>, curcumin, and shikonin with 5, 10, 25, and 50% concentration were applied on 33 healthy Chinese subjects using the T.R.U.E. TEST® patch test system for 48 h. Photopatch testing was performed on 206 Chinese subjects with predisposed photosensitivity history using the Scandinavian photopatch series, and subjects were irradiated by 50% UVA minimum erythema dose. Photopatch testing of herbal extracts was then performed on subjects diagnosed with PA. <b><i>Results:</i></b> Thirty-three subjects (14 with type III skin and 19 with type IV skin) completed contact patch testing of herbal extracts. <i>Coptis</i> induced a contact allergy (CA) reaction on 2 subjects at 25% concentration and on 2 subjects at 10% concentration. <i>P. amurense</i> induced a CA reaction on 1 subject at 10% concentration and on 1 subject at 5% concentration. Shikonin induced a stimulating reaction on 1 subject at 10% concentration. Curcumin induced a stimulating reaction on 1 subject at 10% concentration. Of the 206 Chinese subjects predisposed for photosensitivity, 10.19% had PA, 16.5% showed CA, and 1.45% had both PA + CA. PA-induced substances were promethazine hydrochloride (15%, <i>n</i> = 31), chlorpromazine hydrochloride (10.84%, <i>n</i> = 19), perfume mix (5.82%, <i>n</i> = 12), atranorin (3.39%, <i>n</i> = 7), 6-methyl coumarine (3.39%, <i>n</i> = 7), balsam Peru (1.94%, <i>n</i> = 4), fentichlor (1.94%, <i>n</i> = 4), 3,3′,4′,5-tetrachloro salicylanilide (0.97%, <i>n</i> = 2), hexachlorophene (0.97%, <i>n</i> = 2), chlorhexidine digluconate (0.97%, <i>n</i> = 2), and 4-aminobenzoic acid 2-hydroxy-4-methoxybenzophenone (0.97%, <i>n</i> = 2). <i>Coptis</i> at 25, 10, and 5% concentration and <i>P. amurense</i>, shikonin, and curcumin each at 10 and 5% concentration induced negative photopatch test results in all 10 photosensitive subjects. <b><i>Conclusion:</i></b> We have shown that <i>Coptis</i>, shikonin, or curcumin at 5% concentration in cosmetics could be applied safely without inducing contact allergic and photosensitive reactions on the skin. These findings advance the understanding of herbal extract use in cosmetic ingredients as related to the fields of dermatopharmacology and dermatotoxicology.

scholarly journals Patch test results in patients with suspected contact allergy to shoes – retrospective IVDK data analysis 2009–2018

2021 ◽  
Author(s):  
Stephan Traidl ◽  
Thomas Werfel ◽  
Franziska Ruëff ◽  
Dagmar Simon ◽  
Claudia Lang ◽  
...  
Keyword(s):  
Data Analysis ◽  
Patch Test ◽  
Contact Allergy ◽  
Test Results

scholarly journals Patch Testing for Contact Allergy and Allergic Contact Dermatitis

2008 ◽  
Vol 1 (1) ◽  
pp. 42-51 ◽  
Author(s):  
Radoslaw Spiewak
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Test ◽  
Contact Allergy ◽  
Diagnostic Methods ◽  
Test Results ◽  
Costs Of Treatment ◽  
Allergic Contact

Contact allergy (CA) is alteration of immune response with readiness to develop an inflammatory reaction against a specific substance of low molecular weight (hapten). The prevalence of CA is estimated at 26-40% among adults, and 21-36% children. A proportion of people with CA will remain asymptomatic, among the rest, the most frequent clinical manifestation is allergic contact dermatitis (ACD) with lifetime prevalence estimated at 10%. Less frequent manifestations include allergic contact stomatitis, conjunctivitis, vaginitis, systemic reactions, implant intolerance, and rarely urticaria, asthma, and allergic rhinitis. Patch test (epicutaneous test) is the gold standard in the diagnosis of CA and ACD: Performing the test significantly increases probability of accurate diagnosis, reduces costs of treatment, and leads to improved patients’ quality of life. Patch test results may be influenced by patient’s medication and health status, and interpretation requires due knowledge and experience. Other diagnostic methods are more laborious and not validated; no in vitro tests are available for routine application at present.

Sign in / Sign up

Export Citation Format

Share Document