The incidence of thyroid cartilage invasion in early-stage laryngeal carcinoma: Our experience on sixty-two patients

2017 ◽  
Vol 43 (1) ◽  
pp. 388-392 ◽  
Author(s):  
H.M. Yener ◽  
M. Yilmaz ◽  
A.B. Karaaltın ◽  
H.C. Inan ◽  
F. Turgut ◽  
...  
Keyword(s):  
Laryngeal Carcinoma ◽  
Early Stage ◽  
Thyroid Cartilage ◽  
Cartilage Invasion

Thyroid cartilage invasion in early-stage squamous cell carcinoma involving the anterior commissure

Head & Neck ◽  
2011 ◽  
Vol 34 (10) ◽  
pp. 1476-1479 ◽  
Author(s):  
Dana M. Hartl ◽  
Guillaume Landry ◽  
Stéphane Hans ◽  
Patrick Marandas ◽  
Odile Casiraghi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Anterior Commissure ◽  
Thyroid Cartilage ◽  
Cartilage Invasion

Diffusion-weighted MRI in diagnosing thyroid cartilage invasion in laryngeal carcinoma

2013 ◽  
Vol 271 (9) ◽  
pp. 2511-2516 ◽  
Author(s):  
Mohamed S Taha ◽  
Ossama Hassan ◽  
Mohamed Amir ◽  
Togan Taha ◽  
Magdy Amin Riad
Keyword(s):  
Laryngeal Carcinoma ◽  
Thyroid Cartilage ◽  
Diffusion Weighted Mri ◽  
Cartilage Invasion ◽  
Diffusion Weighted

scholarly journals Thyroid Gland Invasion in Laryngeal Carcinoma

2018 ◽  
Vol 32 (2) ◽  
pp. 22-24 ◽  
Author(s):  
Maria Concepcion F. Vitamog ◽  
Samantha S. Castañeda
Keyword(s):  
Thyroid Gland ◽  
Total Thyroidectomy ◽  
Laryngeal Carcinoma ◽  
Total Laryngectomy ◽  
Thyroid Cartilage ◽  
Case Series ◽  
Government Hospital ◽  
Retrospective Case ◽  
Cartilage Invasion ◽  
Poorly Differentiated

Objective: To determine the prevalence of, and describe transglottic cancer with thyroid cartilage invasion as a possible risk for, thyroid gland invasion in a series of patients with laryngeal carcinoma who underwent total laryngectomy with thyroidectomy. Methods Study Design:            Retrospective case series Setting:                       Tertiary government hospital Subjects:                    61 laryngeal carcinoma patients who underwent total laryngectomy with hemi- or total thyroidectomy from January 2010 to August 2017. Results Out of 61 patients with laryngeal carcinoma, 11 patients had supraglottic, 11 glottic, 2 subglottic and 37 had transglottic involvement. Eleven had thyroid cartilage invasion, all of whom had transglottic tumors. Of these 11 patients, only 1 had thyroid gland invasion. This was a case of a 78 year-old male patient, with poorly differentiated SCC stage IVa transglottic tumor with thyroid cartilage invasion. Conclusion Thyroid gland invasion was uncommon in our sample of laryngeal carcinoma patients who underwent laryngectomy and thyroidectomy. Although transglottic involvement with thyroid cartilage invasion may increase the risk of thyroid gland invasion, it could not be confirmed by our series. Perhaps thyroidectomy should not be routinely performed on all patients with laryngeal carcinoma who undergo total laryngectomy, but more rigorous studies are needed to establish this.   Keywords: laryngeal carcinoma, transglottic, thyroid cartilage invasion, thyroid gland invasion, thyroidectomy  

scholarly journals Organ motion in linac-based SBRT for glottic cancer

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Annarita Perillo ◽  
Valeria Landoni ◽  
Alessia Farneti ◽  
Giuseppe Sanguineti
Keyword(s):  
Early Stage ◽  
Displacement Vector ◽  
Thyroid Cartilage ◽  
Three Dimensional ◽  
Target Volume ◽  
Glottic Cancer ◽  
Organ Motion ◽  
Delivery Times ◽  
Significant Difference ◽  
Pre Treatment

Abstract Purpose The purpose of this study is to evaluate inter- and intra-fraction organ motion as well as to quantify clinical target volume (CTV) to planning target volume (PTV) margins to be adopted in the stereotactic treatment of early stage glottic cancer. Methods and materials Stereotactic body radiotherapy (SBRT) to 36 Gy in 3 fractions was administered to 23 patients with early glottic cancer T1N0M0. Patients were irradiated with a volumetric intensity modulated arc technique delivered with 6 MV FFF energy. Each patient underwent a pre-treatment cone beam computed tomography (CBCT) to correct the setup based on the thyroid cartilage position. Imaging was repeated if displacement exceeded 2 mm in any direction. CBCT imaging was also performed after each treatment arc as well as at the end of the delivery. Swallowing was allowed only during the beam-off time between arcs. CBCT images were reviewed to evaluate inter- and intra-fraction organ motion. The relationships between selected treatment characteristics, both beam-on and delivery times as well as organ motion were investigated. Results For the population systematic (Ʃ) and random (σ) inter-fraction errors were 0.9, 1.3 and 0.6 mm and 1.1, 1.3 and 0.7 mm in the left-right (X), cranio-caudal (Y) and antero-posterior (Z) directions, respectively. From the analysis of CBCT images acquired after treatment, systematic (Ʃ) and random (σ) intra-fraction errors resulted 0.7, 1.6 and 0.7 mm and 1.0, 1.5 and 0.6 mm in the X, Y and Z directions, respectively. Margins calculated from the intra-fraction errors were 2.4, 5.1 and 2.2 mm in the X, Y and Z directions respectively. A statistically significant difference was found for the displacement in the Z direction between patients irradiated with > 2 arcs versus ≤ 2 arcs, (MW test, p = 0.038). When analyzing mean data from CBCT images for the whole treatment, a significant correlation was found between the time of delivery and the three dimensional displacement vector (r = 0.489, p = 0.055), the displacement in the Y direction (r = 0.553, p = 0.026) and the subsequent margins to be adopted (r = 0.626, p = 0.009). Finally, displacements and the subsequent margins to be adopted in Y direction were significantly greater for treatments with more than 2 arcs (MW test p = 0.037 and p = 0.019, respectively). Conclusions In the setting of controlled swallowing during treatment delivery, intra-fraction motion still needs to be taken into account when planning with estimated CTV to PTV margins of 3, 5 and 3 mm in the X, Y and Z directions, respectively. Selected treatments may require additional margins.

scholarly journals Comparative Study between CT and MRI in Assessment of Laryngeal Cartilage Invasion in Laryngeal Carcinoma

2021 ◽  
Vol 89 (6) ◽  
pp. 873-880
Author(s):  
SHAIMA F. ELKHOLY, M.D.; MOHAMED A. KANDEEL, M.Sc. ◽  
MOMEN A. AMEEN HAMELA RAMY E. IBRAHIM ASAAD
Keyword(s):  
Comparative Study ◽  
Laryngeal Carcinoma ◽  
Laryngeal Cartilage ◽  
Cartilage Invasion ◽  
Ct And Mri

scholarly journals Outcome of Early-Stage Glottic Laryngeal Carcinoma Patients Treated with Radical Radiotherapy Using Different Techniques

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Oguz Cetinayak ◽  
Ersoy Dogan ◽  
Ahmet Kuru ◽  
Nesrin Akturk ◽  
Barbaros Aydin ◽  
...  
Keyword(s):  
Local Control ◽  
Laryngeal Carcinoma ◽  
Early Stage ◽  
Anterior Commissure ◽  
Conventional Technique ◽  
Radical Radiotherapy ◽  
Treatment Techniques ◽  
Median Total Dose ◽  
Effective Treatment Modality ◽  
Laryngeal Carcinomas

Purpose. The aim was to evaluate the treatment outcomes and prognostic characteristics of patients with early-stage glottic laryngeal carcinoma who underwent radical radiotherapy (RT) with different techniques. Patients and Methods. Radiotherapy was applied using the 2D conventional technique between 1991 and 2004 (130 patients), 3DCRT until 2014 (125 patients), and by VMAT until January 2017 (44 patients). Clinical T stages were 38 (12.7%) for Tis, 209 (69.9%) for T1, and 52 (17.4%) for T2. Radiotherapy technique and energy, anterior commissure involvement, and stage were analyzed as prognostic factors. Results. The median total dose was 66 (50–70) Gy, and median follow-up time was 72 (3–288) months; 5-year disease-specific survival (DSS) rates were 95.8%, 95.5%, and 88.6%, respectively, in Tis, T1, and T2 stages. In multivariate analyses, anterior commissure involvement was found significant for all survival and local control rates. The patients treated with VMAT technique had better local control and DSS rates. However, these results were not statistically significant. Conclusion. In early-stage laryngeal carcinomas, radical RT is a function sparing and effective treatment modality, regardless of treatment techniques.

Computerized Axial Tomography in the Assessment of Thyroid Cartilage Invasion by Laryngeal Carcinoma: A Prospective Study

1980 ◽  
Vol 88 (6) ◽  
pp. 726-733 ◽  
Author(s):  
Marshall D. Nathan ◽  
Taher El Gammal ◽  
James H. Hudson
Keyword(s):  
Soft Tissue Tumor ◽  
Thyroid Cartilage ◽  
Human Study ◽  
Study Group ◽  
Axial Tomography ◽  
Cartilage Invasion ◽  
Radiographic Technique ◽  
Carcinoma Of The Larynx ◽  
Computerized Axial Tomography ◽  
A Prospective Study

The purpose of this study was to assess the value of computerized axial tomography (CAT) in canine larynges that exhibit controlled surgical defects, and in 18 patients with biopsy-proved epidermoid carcinoma of the larynx who were studied prospectively. Five canine larynges with sequential surgical defects of 0 mm, 5 mm, 10 mm, and 15 mm were studied by CAT in order to evaluate our ability to identify defects in the thyroid cartilage. A 5-mm collimator with overlapping sections at 3-mm intervals and a 13-mm collimator with 5-mm overlapping sections were both used for each stage of the experiment. Results show significantly improved resolution with the 5-mm collimator compared with the 13-mm unit. In the human study group, results demonstrated excellent (100%) soft-tissue tumor site correlation. It appears from this study that we still lack a highly reliable radiographic technique for evaluating preoperatively with accuracy the integrity of the thyroid cartilage in the patient with carcinoma of the larynx.

CT-scan prediction of thyroid cartilage invasion for early laryngeal squamous cell carcinoma

2012 ◽  
Vol 270 (1) ◽  
pp. 287-291 ◽  
Author(s):  
Dana M. Hartl ◽  
Guillaume Landry ◽  
François Bidault ◽  
Stéphane Hans ◽  
Morbize Julieron ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Ct Scan ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Thyroid Cartilage ◽  
Cartilage Invasion
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