Altered oesophageal mechanosensitivity of secondary peristalsis as a pathophysiological marker in patients with globus sensation

2017 ◽  
Vol 43 (1) ◽  
pp. 306-311 ◽  
Author(s):  
W-Y. Lei ◽  
J-S. Hung ◽  
T-T. Liu ◽  
C-H. Yi ◽  
C-L. Chen
Keyword(s):  
Globus Sensation ◽  
Secondary Peristalsis

Altered Esophageal Mechanosensitivity of Secondary Peristalsis as a Pathophysiological Marker in Patients with Globus Sensation

2017 ◽  
Vol 152 (5) ◽  
pp. S320-S321
Author(s):  
Chien-Lin Chen ◽  
Wei-Yi Lei ◽  
Jui-Sheng Hung ◽  
Chih-Hsun Yi ◽  
Fabio Pace ◽  
...  
Keyword(s):  
Globus Sensation ◽  
Secondary Peristalsis

Globus Sensation and GERD

2003 ◽  
Vol 54 (5) ◽  
pp. 347-351
Author(s):  
Yusuke Watanabe
Keyword(s):  
Globus Sensation

scholarly journals Globus sensation due to a metastasis of a malignant melanoma

2021 ◽  
Vol 14 (4) ◽  
pp. e242755
Author(s):  
Charlotte Bultynck ◽  
Gregory Clement ◽  
Paul Lambert ◽  
Joke Patou
Keyword(s):  
Malignant Melanoma ◽  
Globus Sensation

scholarly journals Giant Fibrovascular Polyp as an Unusual Cause of Globus Pharyngeus

2021 ◽  
pp. 014556132110039
Author(s):  
Jelena Sotirović ◽  
Ljubomir Pavićević ◽  
Stanko Petrović ◽  
Saša Ristić ◽  
Aleksandar Perić
Keyword(s):  
Differential Diagnosis ◽  
Asymptomatic Patient ◽  
Histopathological Examination ◽  
Complete Resection ◽  
Airway Compromise ◽  
Endoscopic Removal ◽  
Globus Sensation ◽  
Fibrovascular Polyp ◽  
History Of ◽  
Fatal Complications

Differential diagnosis of globus sensation in an otherwise asymptomatic patient should include hypopharyngeal fibrovascular polyp to avoid potentially fatal complications like airway compromise following regurgitation. We present a case of a 74-year-old man with a 13-cm long hypopharyngeal fibrovascular polyp with 9 months history of globus sensation. A narrow stalk of the giant polyp allowed endoscopic removal and complete resection with the CO2 laser. Histopathological examination was conclusive for the fibrovascular polyp.

scholarly journals Influence of GABA-B Agonist Baclofen on Capsaicin-Induced Excitation of Secondary Peristalsis in Humans

2017 ◽  
Vol 8 (10) ◽  
pp. e120 ◽  
Author(s):  
Wei-Yi Lei ◽  
Jui-Sheng Hung ◽  
Tso-Tsai Liu ◽  
Chih-Hsun Yi ◽  
Chien-Lin Chen
Keyword(s):  
Secondary Peristalsis

Tu1426 Differences in the Control of Distension-Induced Secondary Peristalsis in Human Esophagus: the Role of 5-HT4 Receptor Versus TRPV1 Receptor

2015 ◽  
Vol 148 (4) ◽  
pp. S-887
Author(s):  
Chien-Lin Chen ◽  
Tso-Tsai Liu ◽  
Chih-Hsun Yi ◽  
Wei-Yi Lei ◽  
Jui-Sheng Hung
Keyword(s):  
Trpv1 Receptor ◽  
Human Esophagus ◽  
Secondary Peristalsis

Comparison of primary and secondary esophageal peristalsis in humans: effect of atropine

1991 ◽  
Vol 260 (1) ◽  
pp. G52-G57 ◽  
Author(s):  
W. G. Paterson ◽  
T. T. Hynna-Liepert ◽  
M. Selucky
Keyword(s):  
Neural Pathways ◽  
Esophageal Peristalsis ◽  
Healthy Male ◽  
Double Blind ◽  
Primary Peristalsis ◽  
Lower Amplitude ◽  
Catheter System ◽  
The Subject ◽  
Esophageal Sphincter ◽  
Secondary Peristalsis

To determine whether physiological differences exist between primary (swallow-induced) and secondary (distension-induced) peristalsis in humans, 10 healthy male volunteers underwent esophageal manometry on 2 consecutive days using a perfused intraluminal catheter system that incorporated a latex balloon. Initially the catheter was positioned so that the balloon was centered 16 cm above the lower esophageal sphincter (LES), and intraluminal pressures were recorded 21, 11, 6, and 1 cm above the LES. After a series of wet swallows, dry swallows, and balloon distensions, the catheter was repositioned so that the balloon was 6 cm above the LES and pressures were recorded 1 and 11 cm above the LES. A series of balloon distensions were repeated in this position, and the subject was then given either atropine (10 micrograms/kg iv) or placebo in a double-blind randomized fashion (on consecutive days). The protocol was then repeated in reverse order. Distension-induced responses aboral to the balloon with the balloon located 16 cm above the LES were 1) of lower amplitude, 2) more often nonperistaltic, and 3) less atropine sensitive than swallow-induced contractions at comparable sites. With the balloon located distally (6 cm above LES) contractions induced at the 11-cm site (i.e., orad to the balloon) were much more atropine sensitive than contractions induced at the same site when the balloon was located proximally (i.e., 16 cm above LES). These data suggest that, contrary to previous reports, secondary peristalsis differs significantly from primary peristalsis. Furthermore, atropine differentially effects these two types of peristalsis, suggesting that the neural pathways involved are dissimilar.

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