scholarly journals Effects of the local administration of antibiotics on bone formation around dental implants in animal models: a systematic review and meta‐analysis

2020 ◽  
Vol 31 (S20) ◽  
pp. 200-200
Author(s):  
Ali Alenezi ◽  
Chrcanovic Bruno
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Bone Formation ◽  
Dental Implants ◽  
Meta Analysis ◽  
Local Administration

scholarly journals Synthetic Blocks for Bone Regeneration: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 20 (17) ◽  
pp. 4221 ◽  
Author(s):  
Tumedei ◽  
Savadori ◽  
Del Fabbro
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Bone Formation ◽  
Meta Analysis ◽  
In Vivo Studies ◽  
Control Group ◽  
Bone Augmentation ◽  
New Bone Formation ◽  
Bias Assessment

This systematic review is aimed at evaluating the effectiveness of synthetic block materials for bone augmentation in preclinical in vivo studies. An electronic search was performed on Pubmed, Scopus, EMBASE. Articles selected underwent risk-of-bias assessment. The outcomes were: new bone formation and residual graft with histomorphometry, radiographic bone density, soft tissue parameters, complications. Meta-analysis was performed to compare new bone formation in test (synthetic blocks) vs. control group (autogenous blocks or spontaneous healing). The search yielded 214 articles. After screening, 39 studies were included, all performed on animal models: rabbits (n = 18 studies), dogs (n = 4), rats (n = 7), minipigs (n = 4), goats (n = 4), and sheep (n = 2). The meta-analysis on rabbit studies showed significantly higher new bone formation for synthetic blocks with respect to autogenous blocks both at four-week (mean difference (MD): 5.91%, 95% confidence intervals (CI): 1.04, 10.79%, p = 0.02) and at eight-week healing (MD: 4.44%, 95% CI: 0.71, 8.17%, p = 0.02). Other animal models evidenced a trend for better outcomes with synthetic blocks, though only based on qualitative analysis. Synthetic blocks may represent a viable resource in bone regenerative surgery for achieving new bone formation. Differences in the animal models, the design of included studies, and the bone defects treated should be considered when generalizing the results. Clinical studies are needed to confirm the effectiveness of synthetic blocks in bone augmentation procedures.

Effects of sleep deprivation on maternal behaviour in animal models: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Gabriel N. Pires ◽  
Thainá B. Oliveira ◽  
Victoria F. F. Mello ◽  
Andréia G. Bezerra ◽  
Cathalijn H. C. Leenaars ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Sleep Deprivation ◽  
Meta Analysis ◽  
Maternal Behaviour

Clinical evidence on titanium–zirconium dental implants: a systematic review and meta-analysis

2016 ◽  
Vol 45 (7) ◽  
pp. 842-850 ◽  
Author(s):  
P. Altuna ◽  
E. Lucas-Taulé ◽  
J. Gargallo-Albiol ◽  
O. Figueras-Álvarez ◽  
F. Hernández-Alfaro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implants ◽  
Clinical Evidence ◽  
Meta Analysis ◽  
Titanium Zirconium

scholarly journals Efficacy of Deferoxamine in Animal Models of Intracerebral Hemorrhage: A Systematic Review and Stratified Meta-Analysis

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0127256 ◽  
Author(s):  
Han-Jin Cui ◽  
Hao-yu He ◽  
A-Li Yang ◽  
Hua-Jun Zhou ◽  
Cong Wang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Animal Models ◽  
Intracerebral Hemorrhage ◽  
Meta Analysis
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