Early biocompatibility of poly (ethylene glycol) hydrogel barrier materials for guided bone regeneration. Anin vitrostudy using human gingival fibroblasts (HGF-1)

2012 ◽  
Vol 25 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Christer Dahlin ◽  
Anna Johansson ◽  
Maria Hoffman ◽  
Aart Molenberg
Keyword(s):  
Ethylene Glycol ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Human Gingival Fibroblasts ◽  
Gingival Fibroblasts ◽  
Poly Ethylene Glycol ◽  
Barrier Materials ◽  
Poly Ethylene

Hydrogels from chitosan crosslinked with poly(ethylene glycol) diacid as bone regeneration materials

e-Polymers ◽  
2004 ◽  
Vol 4 (1) ◽  
Author(s):  
Rosica Mincheva ◽  
Nevena Manolova ◽  
Rumen Sabov ◽  
Galen Kjurkchiev ◽  
Iliya Rashkov
Keyword(s):  
Ethylene Glycol ◽  
Bone Regeneration ◽  
Heating Temperature ◽  
Polymer Networks ◽  
Crosslinking Agent ◽  
Poly Ethylene Glycol ◽  
Simple Method ◽  
Equilibrium Degree ◽  
Poly Ethylene

Abstract A simple method to covalently crosslink chitosan using poly(ethylene glycol) diacid as crosslinking agent is proposed. Networks net-chitosan-ι- PEG(COOH)2 were obtained by heating chitosan in aqueous PEG600(COOH)2 solutions at a temperature higher than 60°C. IR spectroscopy revealed the formation of amide bonds. It is shown that the obtained chemical networks are pH-sensitive hydrogels with enhanced hydrophilicity. The equilibrium degree of swelling of the hydrogels is determined by the conditions of their preparation - heating temperature and mole ratio between chitosan and the crosslinker. The ability of the polymer networks to facilitate bone regeneration processes was shown by in vivo implantation experiments.

Poly(ethylene glycol) hydrogels cross-linked by hydrolyzable polyrotaxane containing hydroxyapatite particles as scaffolds for bone regeneration

2005 ◽  
Vol 16 (12) ◽  
pp. 1611-1621 ◽  
Author(s):  
Mariko Fujimoto ◽  
Masatsugu Isobe ◽  
Satoshi Yamaguchi ◽  
Teruo Amagasa ◽  
Akihiko Watanabe ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Bone Regeneration ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Extrudable salicylic acid-based poly(anhydride-esters) for injectable drug releasing applications

2019 ◽  
Vol 34 (2) ◽  
pp. 178-189 ◽  
Author(s):  
Sabrina S Snyder ◽  
Yue Cao ◽  
Kathryn E Uhrich
Keyword(s):  
Salicylic Acid ◽  
Ethylene Glycol ◽  
Drug Loading ◽  
Invasive Procedure ◽  
Minimal Invasive ◽  
Poly Ethylene Glycol ◽  
Barrier Materials ◽  
Injectable Drug ◽  
Poly Ethylene

Injectable biomaterials have attracted more and more interest owing to their advantages over traditional open surgeries: minimal invasive procedure and ease of handling. Commonly used synthetic injectable polymers exhibited low drug loading and poor biodegradability. In this work, we describe a novel series of degradable copolymers comprising salicylic acid–based poly(anhydride-esters) and poly(ethylene glycol) subunits suitable for injectable drug releasing applications. By tuning the rheology properties, these salicylic acid–based poly(anhydride-esters) and poly(ethylene glycol) copolymers may function as injectable drug delivery vehicles that deliver salicylic acid at the injury site. These copolymers were designed to have glass transition temperatures (Tg) below 0ºC, resulting in extrudable polymers that behave like viscous fluids at room temperature. Salicylic acid–based poly(anhydride-esters) and poly(ethylene glycol) copolymers of different ratios (2:1, 1:1, and 1:2 salicylic acid–based poly(anhydride-esters) and poly(ethylene glycol)) were synthesized and characterized by nuclear magnetic resonance and Fourier-transform infrared spectroscopies. Their shear viscosities were determined both at room and physiological temperatures. The in vitro drug release profiles, cytotoxicity, and anti-inflammatory activities were assessed. The shear viscosities were found to compare favorably with current injectable barrier materials on the market.

Synthesis of bioactive poly(ethylene glycol)/SiO2-CaO-P2O5 hybrids for bone regeneration

2012 ◽  
Vol 32 (4) ◽  
pp. 707-711 ◽  
Author(s):  
Wei Liu ◽  
Xiaohong Wu ◽  
Hongbing Zhan ◽  
Fuhua Yan
Keyword(s):  
Ethylene Glycol ◽  
Bone Regeneration ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

PIEZOELECTRIC PROPERTIES OF POLY(3-HYDROXYBUTYRATE-CO-3-HEDROXYBUTYRATE)-CO-POLY(ETHYLENE GLYCOL) PRODUCED BY CONTROLLED MICROBIOLOGICAL BIOSYNTHESIS

2019 ◽  
Vol 10 (10) ◽  
Author(s):  
Anton Bonartsev ◽  
Vera Voinova ◽  
Elizaveta Akoulina ◽  
Andrey Dudun ◽  
Irina Zharkova ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Piezoelectric Properties ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Thermosensitives hydrogels based on poly (ethylene glycol): I. Synthesis, characterization and release

2007 ◽  
Vol 32 (5) ◽  
pp. 431-446 ◽  
Author(s):  
Tahar Bartil ◽  
Mahmoud Bounekhel ◽  
Cedric Calberg ◽  
Robert Jerome
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Quantifying Heart Valve Interstitial Cell Contractile State Using Highly Tunable Poly(Ethylene Glycol) Hydrogels

2019 ◽  
Author(s):  
Alex Khang ◽  
Andrea Gonzalez Rodriguez ◽  
Megan E. Schroeder ◽  
Jacob Sansom ◽  
Emma Lejeune ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Heart Valve ◽  
Interstitial Cell ◽  
Poly Ethylene Glycol ◽  
Contractile State ◽  
Poly Ethylene
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