scholarly journals Development and Applications of Porous Tantalum Trabecular Metal-Enhanced Titanium Dental Implants

2013 ◽  
Vol 16 (6) ◽  
pp. 817-826 ◽  
Author(s):  
Sompop Bencharit ◽  
Warren C. Byrd ◽  
Sandra Altarawneh ◽  
Bashir Hosseini ◽  
Austin Leong ◽  
...  
2019 ◽  
Vol 121 (3) ◽  
pp. 404-410 ◽  
Author(s):  
Alexander R. Edelmann ◽  
Devang Patel ◽  
Riley K. Allen ◽  
Chad J. Gibson ◽  
Al M. Best ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Marko Vuletić ◽  
Ivica Pelivan ◽  
Dragana Gabrić

Oropharyngeal cancer (OPC) represents a significant portion of head and neck cancers. In most cases, it is localised in the soft palate, lingual and palatine tonsils, base of the tongue, and the surrounding tissues. Alcohol and tobacco exposure are well-known evidence-based risk factors for developing OPC; however, over the last decade, there has been a rapid increase in OPC linked to human papillomavirus (HPV). Dental implant therapy faces many challenges related to immediate and long-term success, and patients who are rehabilitated with implant prosthodontic therapy often have numerous comorbidities. Tantalum is a rare transitional metal element which has high corrosion resistance and is extremely inert. Porous tantalum trabecular metal (PTTM) has high volumetric porosity, a low modulus of elasticity, and very high friction. PTTM implant surface enhancement allows “osseoincorporation,” which means the neovascularisation and formation of new bone directly onto the implant. A 65-year-old patient presented to the Department of Oral Surgery of Clinical Hospital Centre Zagreb after resection of the mandible due to OPC had oral rehabilitation. Three Zimmer Biomet Trabecular Metal™ implants ( 4.1 × 10   mm ) were inserted in the area of lower left first incisor, lower left second premolar, and lower right second premolar, and after four months, a new upper partial denture and the bar-retained mandibular overdenture were made. Implant prosthodontic rehabilitation of head and neck cancer patients is usually challenging in terms of achieving an improvement in its main aim, quality of life; however, today it is a safe and reliable therapy. Although radiation therapy may negatively affect the patient’s oral condition and influence the short- and long-term success of the implant, the presented case report showed that the excellent properties of PTTM-enhanced dental implants may give great basis for future comparative researches of using these implants in the treatment of oncologic patients.


2019 ◽  
Vol 45 (3) ◽  
pp. 173-180 ◽  
Author(s):  
Sompop Bencharit ◽  
Thiago Morelli ◽  
Silvana Barros ◽  
Jackson T. Seagroves ◽  
Steven Kim ◽  
...  

Porous tantalum trabecular metal (PTTM) has long been used in orthopedics to enhance neovascularization, wound healing, and osteogenesis; recently, it has been incorporated into titanium alloy dental implants. However, little is known about the biological responses to PTTM in the human oral cavity. We have hypothesized that, compared with conventional titanium alloy, PTTM has a greater expression of genes specific to neovascularization, wound healing, and osteogenesis during the initial healing period. Twelve subjects requiring at least 4 implants in the mandible were enrolled. Four 3 × 5mm devices, including 2 titanium alloy tapered screws and 2 PTTM cylinders, were placed in the edentulous mandibular areas using a split-mouth design. One device in each group was trephined for analysis at 2 and 4 weeks after placement. RNA microarray analysis and ingenuity pathway analysis were used to analyze osteogenesis gene expression and relevant signaling pathways. Compared to titanium alloy, PTTM samples exhibited significantly higher expressions of genes specific to cell neovascularization, wound healing, and osteogenesis. Several genes—including bone morphogenic proteins, collagens, and growth factors—were upregulated in the PTTM group compared to the titanium alloy control. PTTM materials may enhance the initial healing of dental implants by modifying gene expression profiles.


2016 ◽  
Vol 29 (6) ◽  
pp. 649-655 ◽  
Author(s):  
Georgios E. Romanos ◽  
Rafael Arcesio Delgado-Ruiz ◽  
Danielle Sacks ◽  
Josè Luis Calvo-Guirado

1999 ◽  
Vol 8 (3) ◽  
pp. 295-302 ◽  
Author(s):  
Guaracilei Maciel Vidigal ◽  
Liane Cassol Argenta Aragones ◽  
Aguinaldo Campos ◽  
Mario Groisman

Author(s):  
David Soto-Peñaloza ◽  
José Javier Martín-de-Llano ◽  
Carmen Carda-Batalla ◽  
Miguel Peñarrocha-Diago ◽  
David Peñarrocha-Oltra

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