scholarly journals Longitudinal analysis of cotton wool spots in COVID ‐19 with high resolution spectral domain optical coherence tomography and optical coherence tomography angiography

2021 ◽  
Author(s):  
Ashish Markan ◽  
Reema Bansal ◽  
Nitin Gautam ◽  
Chirag Ahuja ◽  
Aniruddha Agarwal ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Longitudinal Analysis ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cotton Wool ◽  
Cotton Wool Spots

Features of cotton wool spots in diabetic retinopathy: a spectral-domain optical coherence tomography angiography study

2020 ◽  
Vol 40 (7) ◽  
pp. 1625-1640 ◽  
Author(s):  
Amir Mahdjoubi ◽  
Youcef Bousnina ◽  
Gaelle Barrande ◽  
Faïza Bensmaine ◽  
Sadri Chahed ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cotton Wool ◽  
Cotton Wool Spots

Optical coherence tomography angiography characterization of acute and late stage Purtscher retinopathy

2018 ◽  
Vol 28 (4) ◽  
pp. NP1-NP6 ◽  
Author(s):  
Pedro Gil ◽  
Miguel Raimundo ◽  
João P Marques ◽  
João Póvoa ◽  
Rufino Silva
Keyword(s):  
Optical Coherence Tomography ◽  
Late Stage ◽  
Optical Coherence Tomography Angiography ◽  
Road Traffic ◽  
Optical Coherence ◽  
Cotton Wool ◽  
Fiber Layer ◽  
Cotton Wool Spots ◽  
Purtscher Retinopathy

Purpose: To report a case of Purtscher retinopathy imaged with optical coherence tomography angiography. Methods: Case-report. Left eye fundoscopic examination in a 21-year old male after a road traffic accident with chest compression revealed multiple peri-papillary cotton-wool spots and intra- and pre-retinal hemorrhages. A diagnosis of Purtscher retinopathy was assumed. Results: In both the superficial and deep retinal plexuses, acute stage optical coherence tomography angiography identified multiple irregular areas of capillary non-perfusion that extended beyond the clinically visible peri-papillary cotton-wool spots. At 5-month follow-up, despite the clearing of visible cotton-wool spots, there were still permanent areas of irregular capillary non-perfusion and inner retina atrophy. These sequelae, along with a decrease in the peri-papillary retinal nerve fiber layer thickness, were consistent with a suboptimal visual outcome and a dense inferior arcuate scotoma. Conclusion: Baseline and follow-up optical coherence tomography angiography was able to detect, quantify, and map focal microvascular abnormalities at the level of the superficial and deep inner retinal vascular plexuses. These lesions were consistent with late stage structural and functional sequelae, conferring them prognostic value.

In Vivo Histology of Cotton-Wool Spots Using High-Resolution Optical Coherence Tomography

2006 ◽  
Vol 141 (4) ◽  
pp. 748-750 ◽  
Author(s):  
Igor Kozak ◽  
Dirk-Uwe Bartsch ◽  
Lingyun Cheng ◽  
William R. Freeman
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Optical Coherence ◽  
Cotton Wool ◽  
Cotton Wool Spots

Is high-resolution spectral domain optical coherence tomography reliable in nystagmus?

2011 ◽  
Vol 97 (4) ◽  
pp. 534.1-536 ◽  
Author(s):  
Mervyn G Thomas ◽  
Anil Kumar ◽  
John R Thompson ◽  
Frank A Proudlock ◽  
Kees Straatman ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Spectral Domain ◽  
Optical Coherence

scholarly journals Comparison of swept-source versus spectral-domain optical coherence tomography angiography for detection of macular neovascularization

2021 ◽  
Author(s):  
Anna Lentzsch ◽  
Laura Schöllhorn ◽  
Christel Schnorr ◽  
Robert Siggel ◽  
Sandra Liakopoulos
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
En Face ◽  
Increased Sensitivity ◽  
Sensitivity Specificity ◽  
Subretinal Hyperreflective Material

Abstract Purpose To compare swept-source (SS) versus spectral-domain (SD) optical coherence tomography angiography (OCTA) for the detection of macular neovascularization (MNV). Methods In this prospective cohort study, 72 eyes of 54 patients with subretinal hyperreflective material (SHRM) and/or pigment epithelial detachment (PED) on OCT possibly corresponding to MNV in at least one eye were included. OCTA scans were acquired using two devices, the PLEX Elite 9000 SS-OCTA and the Spectralis SD-OCTA. Fluorescein angiography (FA) was used as reference. Two graders independently evaluated en face OCTA images using a preset slab as well as a manually modified slab, followed by a combination of en face and cross-sectional OCTA. Results Sensitivity (specificity) for the automated slabs was 51.7% (93.0%) for SS-OCTA versus 58.6% (95.3%) for SD-OCTA. Manual modification of segmentation increased sensitivity to 79.3% for SS-OCTA but not for SD-OCTA (58.6%). The combination of en face OCTA with cross-sectional OCTA reached highest sensitivity values (SS-OCTA: 82.8%, SD-OCTA: 86.2%), and lowest number of cases with discrepancies between SS-OCTA and SD-OCTA (4.2%). Fleiss kappa as measure of concordance between FA, SS-OCTA, and SD-OCTA was 0.56 for the automated slabs, 0.60 for the manual slabs, and 0.73 (good agreement) for the combination of en face OCTA with cross-sectional OCTA. Concordance to FA was moderate for the automated slabs and good for manual slabs and combination with cross-sectional OCTA of both devices. Conclusion Both devices reached comparable results regarding the detection of MNV on OCTA. Sensitivity for MNV detection and agreement between devices was best when evaluating a combination of en face and cross-sectional OCTA.

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