Usefulness of novel laser speckle flowgraphy-derived variables of the large vessel area in the optic nerve head in normal tension glaucoma

2014 ◽  
Vol 42 (9) ◽  
pp. 887-889 ◽  
Author(s):  
Shigeto Maekawa ◽  
Yukihiro Shiga ◽  
Ryo Kawasaki ◽  
Toru Nakazawa
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Normal Tension Glaucoma ◽  
Laser Speckle ◽  
Large Vessel ◽  
Laser Speckle Flowgraphy ◽  
Vessel Area

scholarly journals Laser speckle flowgraphy derived characteristics of optic nerve head perfusion in normal tension glaucoma and healthy individuals: a Pilot study

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Anna Sophie Mursch-Edlmayr ◽  
Nikolaus Luft ◽  
Dominika Podkowinski ◽  
Michael Ring ◽  
Leopold Schmetterer ◽  
...  
Keyword(s):  
Pilot Study ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Normal Tension Glaucoma ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Healthy Individuals

scholarly journals Association between Optic Nerve Head Microcirculation and Macular Ganglion Cell Complex Thickness in Eyes with Untreated Normal Tension Glaucoma and a Hemifield Defect

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Ayako Anraku ◽  
Kyoko Ishida ◽  
Nobuko Enomoto ◽  
Seiji Takagi ◽  
Hiroyuki Ito ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Optic Nerve Head ◽  
Structural Changes ◽  
Normal Tension Glaucoma ◽  
Cell Complex ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Ganglion Cell Complex ◽  
Fiber Layer

Purpose.We evaluated the association between optic nerve head (ONH) microcirculation and macular ganglion cell complex (mGCC) thickness in patients with untreated normal tension glaucoma (NTG) and a hemifield defect.Methods.The medical records of 47 patients with untreated NTG were retrospectively reviewed. Laser speckle flowgraphy was used to obtain mean blur rate (MBR), a relative measure of blood flow. Average total deviation (TD), mGCC, and the circumpapillary retinal nerve fiber layer (cpRNFL) thickness were also analyzed.Results.All parameters corresponding to the defective hemifield were significantly lower than those corresponding to the normal hemifield. In the defective hemifield, MBR was correlated with TD, mGCC, and cpRNFL thickness. In the normal hemifield, MBR was only correlated with mGCC thickness, and multiple regression analysis showed that mGCC thickness was a significant contributing factor of the MBR.Conclusion.MBR was well correlated with mGCC thickness in eyes with untreated NTG and a hemifield defect. In the normal hemifield, mGCC thickness was a contributing factor of the MBR indicating that ONH circulatory dysfunction may be associated with retinal structural changes in the early stages of glaucoma. A reduction in ONH microcirculation may be an early indicator of the presence and progression of glaucoma.

scholarly journals Gender differences in the influence of obstructive sleep apnea on optic nerve head circulation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Tomoaki Shiba ◽  
Mao Takahashi ◽  
Tadashi Matsumoto ◽  
Yuichi Hori
Keyword(s):  
Gender Differences ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
The Mean

AbstractWe investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), maximum (Max) MBR, and minimum (Min) MBR were evaluated. The parameters were analyzed separately for the tissues, vessels, and throughout the ONH (All). The apnea hypopnea index (AHI: times/hr), the lowest SpO2%, and the mean SpO2% were calculated as indicators of OSA. We investigated which MBR sections are correlated with OSA parameters separately in the men and women. All MBR sections in the women were significantly positively correlated with the lowest SpO2. In the men, no MBR section was correlated with any OSA parameters. The factors contributing independently to MBR-Tissue were height (β = 0.31) and lowest SpO2 (β = 0.30). The lowest SpO2 in the women was significantly positively correlated with Max MBR-Tissue, Max MBR-All, and Min MBR-All. Our results confirmed a gender difference in characteristics of ONH microcirculation in association with OSA.

Comparison of CCD-equipped laser speckle flowgraphy with hydrogen gas clearance method in the measurement of optic nerve head microcirculation in rabbits

2013 ◽  
Vol 108 ◽  
pp. 10-15 ◽  
Author(s):  
Hiroaki Takahashi ◽  
Tetsuya Sugiyama ◽  
Hideki Tokushige ◽  
Takatoshi Maeno ◽  
Toru Nakazawa ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Hydrogen Gas ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Hydrogen Gas Clearance

Association Between Optic Nerve Head Blood Flow Measured Using Laser Speckle Flowgraphy and Radial Arterial Pressure During Aortic Arch Surgery

2018 ◽  
Vol 32 (2) ◽  
pp. 702-708 ◽  
Author(s):  
Hironobu Hayashi ◽  
Masahiro Okamoto ◽  
Hideaki Kawanishi ◽  
Nobuoki Tabayashi ◽  
Toyoaki Matsuura ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Arterial Pressure ◽  
Aortic Arch ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Aortic Arch Surgery
Sign in / Sign up

Export Citation Format

Share Document