scholarly journals Longitudinal Changes in Optic Nerve Head Blood Flow in Normal Rats Evaluated by Laser Speckle Flowgraphy

2016 ◽  
Vol 57 (13) ◽  
pp. 5568 ◽  
Author(s):  
Yasushi Wada ◽  
Tomomi Higashide ◽  
Atsushi Nagata ◽  
Kazuhisa Sugiyama
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Longitudinal Changes

Association Between Optic Nerve Head Blood Flow Measured Using Laser Speckle Flowgraphy and Radial Arterial Pressure During Aortic Arch Surgery

2018 ◽  
Vol 32 (2) ◽  
pp. 702-708 ◽  
Author(s):  
Hironobu Hayashi ◽  
Masahiro Okamoto ◽  
Hideaki Kawanishi ◽  
Nobuoki Tabayashi ◽  
Toyoaki Matsuura ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Arterial Pressure ◽  
Aortic Arch ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Aortic Arch Surgery

Non-invasive measurement techniques for quantitative assessment of optic nerve head blood flow

2019 ◽  
Vol 30 (2) ◽  
pp. 235-244 ◽  
Author(s):  
Fia Vosborg ◽  
Lasse Malmqvist ◽  
Steffen Hamann
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence Tomography Angiography ◽  
Laser Speckle ◽  
Doppler Imaging ◽  
Laser Speckle Flowgraphy ◽  
Colour Doppler ◽  
Non Invasive ◽  
Colour Doppler Imaging

Diseases of the optic nerve head involving changes in blood flow are common. However, the pathophysiology is not always fully understood. Several non-invasive methods for measuring optic nerve head blood flow are available, but currently no gold standard has been established. Methods for measuring blood flow in optic neuropathies including colour Doppler imaging, retinal function imager, optical coherence tomography angiography and laser speckle flowgraphy are reviewed. Ultrasound colour Doppler imaging is a fast measurement technique where several different parameters, especially the blood flow velocity, can be calculated. Though used for many years in ophthalmology, its use is not standardized and it requires significant observer skills. The retinal function imager is a direct method where the haemoglobin in erythrocytes is visualized and blood flow velocities in retinal vessels are calculated from a series of photos. The technique is not suitable for direct measurement of blood flow within the optic nerve head. Laser speckle flowgraphy uses a laser light which creates a light scatter pattern in the tissue. Particles moving in the area causes changes in the speckle pattern from which a relative blood flow can be estimated. It is, however, not known whether optic nerve head microcirculation is measurable with the technique. Optical coherence tomography angiography uses multiple scans to evaluate blood flow with good reproducibility but often problems with artefacts. The technique is continuously being refined and increasingly used in research as a tool for the study of blood flow in retinopathies and optic neuropathies. Most of the conducted studies are based on small sample sizes, but some of the methods show promising results in an optic nerve head blood flow research setting. Further and larger studies are required to provide standardized and comparable measurements before one or more of the methods can be considered clinical helpful in daily practice.

scholarly journals Optic nerve head and retinal blood flow regulation during isometric exercise as assessed with laser speckle flowgraphy

PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0184772 ◽  
Author(s):  
Katarzyna J. Witkowska ◽  
Ahmed M. Bata ◽  
Giacomo Calzetti ◽  
Nikolaus Luft ◽  
Klemens Fondi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Isometric Exercise ◽  
Flow Regulation ◽  
Laser Speckle ◽  
Retinal Blood Flow ◽  
Laser Speckle Flowgraphy ◽  
Blood Flow Regulation

Optic Nerve Head Blood Flow, as Measured by Laser Speckle Flowgraphy, Is Significantly Reduced in Preperimetric Glaucoma

2016 ◽  
Vol 41 (11) ◽  
pp. 1447-1453 ◽  
Author(s):  
Yukihiro Shiga ◽  
Hiroshi Kunikata ◽  
Naoko Aizawa ◽  
Naoki Kiyota ◽  
Yukiko Maiya ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Preperimetric Glaucoma

scholarly journals Gender differences in the influence of obstructive sleep apnea on optic nerve head circulation

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Tomoaki Shiba ◽  
Mao Takahashi ◽  
Tadashi Matsumoto ◽  
Yuichi Hori
Keyword(s):  
Gender Differences ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Laser Speckle ◽  
Laser Speckle Flowgraphy ◽  
Apnea Hypopnea Index ◽  
Obstructive Sleep ◽  
The Mean

AbstractWe investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), maximum (Max) MBR, and minimum (Min) MBR were evaluated. The parameters were analyzed separately for the tissues, vessels, and throughout the ONH (All). The apnea hypopnea index (AHI: times/hr), the lowest SpO2%, and the mean SpO2% were calculated as indicators of OSA. We investigated which MBR sections are correlated with OSA parameters separately in the men and women. All MBR sections in the women were significantly positively correlated with the lowest SpO2. In the men, no MBR section was correlated with any OSA parameters. The factors contributing independently to MBR-Tissue were height (β = 0.31) and lowest SpO2 (β = 0.30). The lowest SpO2 in the women was significantly positively correlated with Max MBR-Tissue, Max MBR-All, and Min MBR-All. Our results confirmed a gender difference in characteristics of ONH microcirculation in association with OSA.

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