Laser-assisted subepithelial keratectomyversusepipolis laser in situ keratomileusis for myopia: a meta-analysis of clinical outcomes

2013 ◽  
Vol 42 (4) ◽  
pp. 323-333 ◽  
Author(s):  
Daizong Wen ◽  
Jinhai Huang ◽  
Xuexi Li ◽  
Giacomo Savini ◽  
Yifan Feng ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Meta Analysis ◽  
Laser In Situ Keratomileusis

scholarly journals Efficacy and Safety of Topical Timolol Eye Drops in the Treatment of Myopic Regression after Laser In Situ Keratomileusis: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaochen Wang ◽  
Guiqiu Zhao ◽  
Jing Lin ◽  
Nan Jiang ◽  
Qian Wang ◽  
...  
Keyword(s):  
Meta Analysis ◽  
Treated Group ◽  
Laser In Situ Keratomileusis ◽  
Control Group ◽  
Eye Drops ◽  
Efficacy And Safety ◽  
China National Knowledge Infrastructure ◽  
Knowledge Infrastructure ◽  
Significant Difference

Aims. The aim of this study was to assess the efficacy and safety of timolol in the treatment of myopic regression after laser in situ keratomileusis (LASIK).Methods. We searched MEDLINE, CENTRAL, EMBASE, China National Knowledge Infrastructure (CNKI), and Chinese Biological Medicine (CBM) from the inception to July 2015 for relevant randomized controlled trials that examined timolol therapy for myopic regression. The methodological quality of the studies included was assessed using the Revman 5.3 software.Results. We included six clinical trials involving 483 eyes in this review, including 246 eyes in treated group and 237 eyes in controlled group. We observed statistically significant improvements on the postoperative SE in the 3 months. However, the change of CCT was not statistically different between the control group and the experimental group. There were fewer cases of IOP, UDVA, and CDVA in treated group having significant difference from the controlled group.Conclusions. Topical timolol could be an effective treatment for reduction of myopic regression especially the spherical errors after myopic LASIK. Further RCTs with larger sample sizes for these trials are warranted to determine the efficacy and limitation for myopic regression after LASIK.

Clinical outcomes of wavefront-guided laser in situ keratomileusis: 6-month follow-up

2003 ◽  
Vol 29 (8) ◽  
pp. 1507-1513 ◽  
Author(s):  
Daisuke Aizawa ◽  
Kimiya Shimizu ◽  
Mari Komatsu ◽  
Misae Ito ◽  
Masanobu Suzuki ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Laser In Situ Keratomileusis

scholarly journals Visual differences in topography-guided versus wavefront-optimized LASIK in the treatment of myopia: a Meta-analysis

2021 ◽  
Vol 14 (10) ◽  
pp. 1602-1609
Author(s):  
Peng-Cheng Hu ◽  
◽  
Xian-Hui Wu ◽  
Yan-Qing Li ◽  
Ke-Wei Li ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Web Of Science ◽  
Spherical Aberration ◽  
Meta Analysis ◽  
Laser In Situ Keratomileusis ◽  
Wavefront Aberration ◽  
Spherical Equivalent ◽  
Uncorrected Distance Visual Acuity ◽  
Manifest Refraction

AIM: To investigate the potential differences between topography-guided (TG) and wavefront-optimized (WFO) laser in situ keratomileusis (LASIK) for the treatment of myopia. METHODS: A systematic literature search was performed to determine relevant trials comparing LASIK with TG and WFO from the time of library construction to August 2020, and The PubMed, Cochrane, Web of Science, EMBASE and Chinese databases (i.e. CNKI, CBM, WAN FANG and VIP) were accessed. The data on visual acuity, refractive status and wavefront aberration were retrieved and evaluated from three to six months after surgery. STATA (version 14.0) software was used for statistical analysis. A cumulative Meta-analysis was simultaneously performed. RESULTS: Eleven studies with a total of 1425 eyes were incorporated. No statistically significant differences were evident between TG and WFO ablation in the proportion of eyes achieving an uncorrected distance visual acuity (UCVA) of 20/20 or better (P=0.377), gaining one line or more (P=0.05), postoperative cylinder (P=0.40), vertical coma (P=0.593) and horizontal coma (P=0.957). After TG ablation, the proportion of the patients’ eyes of which postoperative refraction is within ±0.5 diopter of the target refraction was significantly higher than that undergoes WFO (P=0.003). As opposed to the WFO group, manifest refraction spherical equivalent (MRSE; P=0.000) was lower, and UCVA (P=0.005) was better in the TG group. The higher-order aberrations (HOAs; P=0.000), spherical aberration (P=0.000) and coma (P=0.000) were significantly lower in TG group. The cumulative Meta-analysis illustrated that the proportion of eyes achieving UCVA of 20/20 or better, postoperative refraction within ±0.5 diopter, and MRSE has steady between the two groups. CONCLUSION: Both TG-LASIK and WFO-LASIK are safe, effective, and predictable for correcting myopia. TG-LASIK may produce fewer aberration and is more precise than WFO-LASIK.

scholarly journals Clinical outcomes of wavefront-guided laser in situ keratomileusis to treat moderate-to-high astigmatism

2015 ◽  
pp. 1291 ◽  
Author(s):  
Steven Schallhorn ◽  
Jan Venter ◽  
Stephen Hannan ◽  
Keith Hettinger
Keyword(s):  
Clinical Outcomes ◽  
Laser In Situ Keratomileusis

scholarly journals Optical and visual quality comparison of implantable collamer lens and femtosecond laser assisted laser in situ keratomileusis for high myopia correction

2021 ◽  
Vol 14 (5) ◽  
pp. 737-743
Author(s):  
Zheng Jiang ◽  
◽  
Dong-Qiang Luo ◽  
Jiao Chen ◽  
◽  
...  
Keyword(s):  
Visual Acuity ◽  
Femtosecond Laser ◽  
Clinical Outcomes ◽  
High Myopia ◽  
Cutoff Frequency ◽  
Laser In Situ Keratomileusis ◽  
Spherical Equivalent ◽  
Implantable Collamer Lens ◽  
Significant Difference

AIM: To compare clinical outcomes and refractive stability of implantable collamer lens (ICL) implantation and femtosecond laser assisted laser in situ keratomileusis (FS-LASIK) for high myopia correction. METHODS: The Optical Quality Analysis System (OQAS) was used to evaluate clinical outcomes objectively after operation for high myopia correction. We compared the two procedures in terms of 1-year changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), safety index, efficacy index, spherical equivalent, modulation transfer function (MTF) cutoff frequency, strehl ratio (SR) and objective scatter index (OSI). RESULTS: At 1y postoperatively, the safety indices were 1.33±0.27 in ICL group, and 1.17±0.24 in FS-LASIK group. 39.58% in the ICL group and 27.59% in the FS-LASIK group gained CDVA in 2 lines or better than that in preoperative CDVA. The efficacy indices were 1.28±0.22 in ICL group, and 1.13±0.26 in FS-LASIK group. The changes of spherical equivalent from 1wk to 1y postoperatively was -0.12±0.37 D in ICL group, and -0.79±0.58 D in FS-LASIK group (P<0.05). Spherical equivalent within ±0.50 D was achieved in 97.92% in ICL group and 68.97% in FS-LASIK group. MTF cutoff frequency were higher with ICL as compared to FS-LASIK (P<0.05) at each postoperative follow-up stage; for postoperative 1mo later, SR was statistically significant difference between two groups (P<0.05); with no statistically significant difference in OSI between two groups (P>0.05) in postoperative 3mo later. CONCLUSION: ICL implantation and FS-LASIK procedures both provide good safety and predictability in high myopia correction. ICL implantation provides better clinical outcomes and refractive stability than FS-LASIK.

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