Exendin‐4‐based imaging in endogenous hyperinsulinemic hypoglycaemia cohort: A tertiary Endocrine centre experience

2020 ◽  
Vol 93 (6) ◽  
pp. 678-686
Author(s):  
Robin Garg ◽  
Ravikumar Shah ◽  
Ankita Tiwari ◽  
Nilendu Purandare ◽  
Vikram R. Lele ◽  
...  
Keyword(s):  
Hyperinsulinemic Hypoglycaemia

Postprandial Hyperinsulinemic Hypoglycaemia with Positive Selective Calcium Stimulation Test: a case of Idiopathic Reactive Hypoglycaemia.

2008 ◽  
Vol 32 (4) ◽  
pp. 354
Author(s):  
Amir Khattabi ◽  
Martin Labuda ◽  
Francis Bernard ◽  
Barbara Duda ◽  
Nicole Van Rossum ◽  
...  
Keyword(s):  
Stimulation Test ◽  
Reactive Hypoglycaemia ◽  
Calcium Stimulation ◽  
Hyperinsulinemic Hypoglycaemia

scholarly journals Occult insulinoma after oesophagectomy for oesophageal cancer-diagnostic challenges

2021 ◽  
Vol 9 (1) ◽  
pp. 185
Author(s):  
Marta Alexandre Silva ◽  
Maria João Amaral ◽  
Pedro Pinto ◽  
Mónica Martins ◽  
Marco Serôdio ◽  
...  
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Clinical Case ◽  
Gastrointestinal Surgery ◽  
Gastric Surgery ◽  
Diagnostic Investigation ◽  
Post Operative Period ◽  
History Of ◽  
Oesophageal Surgery ◽  
Hyperinsulinemic Hypoglycaemia

Hypoglycaemia in the post-operative period is mainly iatrogenic (related to anti-hyperglycaemic drugs), but can be explained by an endogenous hyperinsulinemic state. In the context of previous gastrointestinal surgery, a form of dumping syndrome can mask hypoglycaemia from an underlying cause, such as an insulinoma. The authors present a clinical case of a male patient who underwent oesophageal surgery for an oesophago-gastric junction adenocarcinoma and developed hypoglycaemic symptoms in the post-operative period, caused by an undiagnosed insulinoma. This case report portraits the diagnostic investigation of a hypoglycaemia state in the post-operative period, narrowing to the workup of an endogenous hyperinsulinemic hypoglycaemia and provides a summary of insulinoma’s treatment. An insulinoma should always be considered in a patient with endogenous hyperinsulinemic hypoglycaemia, even with a history of oesophago-gastric surgery.

scholarly journals Persistent Hypoglycemia and Seizures in Two Months Old Infant Due to Recurrent Hyper insulinemic Hypoglycemia

2020 ◽  
pp. 29-33
Author(s):  
Edwin Dias
Keyword(s):  
Metabolic Disorders ◽  
Plasma Glucose Level ◽  
Neonatal Period ◽  
Genetic Disorders ◽  
Neonatal Seizures ◽  
Neonatal Hypoglycemia ◽  
Common Cause ◽  
Malformation Syndromes ◽  
Intracranial Infections ◽  
Hyperinsulinemic Hypoglycaemia

Persistent hyperinsulinemic hypoglycaemia is the most common cause of recurrent hypoglycaemia. Neonatal hypoglycemia, is a heterogeneous disorder with plasma glucose level of less than 30mg/dL in first 24hrs of life and less than 40mg/dL thereafter, is the most common metabolic cause in newborns. The most important feature of neurologic dysfunction in neonatal period is the occurrence of seizures which can be due to metabolic disorders, genetic disorders, intracranial infections, malformation syndromes, benign neonatal seizures, hemorrhage. Here, we provide a description of a 2 months old infant with Persistent Hypoglycemia and Seizures, treated with hypoglycemic management and antiepileptic drugs

Insulin autoimmune syndrome: a rare cause of spontaneous hypoglycaemia in non-diabetic individuals

2020 ◽  
Vol 13 (12) ◽  
pp. e234448
Author(s):  
Shruthi Ravindra ◽  
Sahana Shetty
Keyword(s):  
Endoscopic Ultrasound ◽  
Insulin Autoantibodies ◽  
Exogenous Insulin ◽  
Insulin Autoimmune Syndrome ◽  
Autoimmune Syndrome ◽  
Pancreatic Tumour ◽  
Biochemical Evaluation ◽  
Antibody Levels ◽  
Hyperinsulinemic Hypoglycaemia

Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycaemia, characterised by recurrent hypoglycaemic episodes secondary to insulin autoantibodies in individuals who are not exposed to exogenous insulin. We are reporting a case of IAS in a 64-year-old gentleman, who presented with predominant postprandial hypoglycaemic episodes. On biochemical evaluation, he was found to have hyperinsulinemic hypoglycaemia. Localisation studies with MRI abdomen and endoscopic ultrasound (EUS) were negative for pancreatic tumour. Tests sent for insulin antibody levels were elevated. The patient was treated with frequent meals, acarbose and glucocorticoids. Patient condition improved and did not experience hypoglycaemia on follow-up.

scholarly journals Treatment and Follow-up in a Case with Diazoxide Treatment-Resistant Hyperinsulinemic Hypoglycaemia

2017 ◽  
pp. 245-248
Author(s):  
Damla Gökşen ◽  
Nurhan Murat ◽  
Özge Altun Köroğlu ◽  
Burçe Emine Yaşar ◽  
Samim Özen ◽  
...  
Keyword(s):  
Treatment Resistant ◽  
Hyperinsulinemic Hypoglycaemia

scholarly journals The treatment of hyperinsulinemic hypoglycaemia in adults: an update

2016 ◽  
Vol 40 (1) ◽  
pp. 9-20 ◽  
Author(s):  
M. V. Davi′ ◽  
◽  
A. Pia ◽  
V. Guarnotta ◽  
G. Pizza ◽  
...  
Keyword(s):  
Hyperinsulinemic Hypoglycaemia

scholarly journals Persistent hyperinsulinemic hypoglycaemia followed as benign infantile convulsion

Seizure ◽  
2003 ◽  
Vol 12 (3) ◽  
pp. 186-187 ◽  
Author(s):  
HIDETO YOSHIKAWA ◽  
TAKESHIGE HONMA ◽  
TOKINARI ABE
Keyword(s):  
Hyperinsulinemic Hypoglycaemia
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