Associations between maternal age at menarche and anthropometric and metabolic parameters in the adolescent offspring

2019 ◽  
Vol 90 (5) ◽  
pp. 702-710 ◽  
Author(s):  
Ye Hong ◽  
Sarah E. Maessen ◽  
Guanping Dong ◽  
Ke Huang ◽  
Wei Wu ◽  
...  
2021 ◽  
Author(s):  
Zahra Jalali ◽  
Saeed Bahrampour ◽  
Parvin Khalili ◽  
Nazanin Jalali ◽  
Ali Esmaeili Nadimi ◽  
...  

2020 ◽  
Vol 5 (1) ◽  
pp. 10-15
Author(s):  
Corina Roxana Onea ◽  
Beáta Máté ◽  
Simona Cernea

AbstractAim: This study evaluated the correlations between metabolic parameters and reproductive health data in women with type 2 diabetes mellitus (T2DM).Material and methods: In this observational retrospective study, data from the medical records of 324 adult women with T2DM attending their regular diabetes check-ups were collected and analyzed (i.e., anthropometric parameters at first outpatient visit and yearly thereafter, first recorded HbA1c and all HbA1c for the entire follow-up duration, as well as obstetrical/gynecological information).Results: Age at the diagnosis of T2DM correlated positively with age at menarche (r = 0.21, [95% CI: 0.09, 0.31], p = 0.0002) and age at menopause (r = 0.18 [95% CI: 0.07, 0.29], p <0.01). Age at menarche correlated negatively with mean weight (r = –0.21 [95% CI: –0.31, –0.10], p: 0.0002) and mean BMI (–0.22 [–0.32, –0.11], p <0.0001) over the follow-up time. Patients with shorter time difference between age at menarche and age at onset of T2DM (≤45 years) had higher mean weight (83.8 ± 14.5 kg vs. 78.4 ± 16.0 kg, p = 0.0001), BMI (33.2 ± 5.6 kg/m2 vs. 31.8 ± 5.7 kg/m2, p <0.05), and HbA1c over time (6.9 ± 0.8% vs. 6.6 ± 0.9%, p <0.0001). Women with T2DM with earlier menarche (<12 years old), with irregular menses during their reproductive life, and ≥3 pregnancies had higher overall BMI, but mean HbA1c were not significantly different. However, women diagnosed with T2DM before menopause had a higher mean HbA1c over time (7.1 ± 0.8% vs. 6.7 ± 0.9%, p <0.01).Conclusion: The BMI correlated with several indicators of reproductive health (earlier menarche, irregular menses, and higher number of pregnancies), while earlier onset of T2DM influenced metabolic control in women with T2DM.


2021 ◽  
Vol 8 (1) ◽  
pp. 103-109
Author(s):  
Putu Dianisa Rosari Dewi ◽  
I Made Arimbawa ◽  
I Gusti Ayu Putu Eka Pratiwi ◽  
I Wayan Gustawan

Background: The age of maternal menarche is thought to be intergenerationally associated with the incidence of overweight and obesity in their offspring, but studies are limited. Objective: To determine the intergenerational relationship between maternal age at menarche and the incidence of childhood obesity and overweight at preschool age. Methods: This research is an analytic cross-sectional study with a cluster sampling method which was conducted in preschool in Denpasar, Bali. Younger maternal menarche was defined as the age of maternal menarche less than 12 years. Overweight and obesity in children are expressed based on the growth curve of the World Health Organization (WHO) Body Mass Index/Age > +2 SD. Results: This study was conducted from October to November 2019 involving 204 samples, with the proportion of overweight and obese children were 28.9%. The mean age of menarche in mothers was 13.28 (SD +1.97) years with 11% of mothers experiencing early maturation. The adjusted ratio prevalence of maternal menarche <11 years was 3.96 (95% CI 1.56-10.08) and the nutritional status of overweight and obesity in the father was 3.22 (95% CI 1.67-6.26). Conclusion: In this study, it was found that there was a relationship between younger maternal age at menarche and overweight and obesity nutritional status in fathers with the incidence of overweight and obesity in children.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hui Wang ◽  
Yunting Zhang ◽  
Ying Tian ◽  
Fei Li ◽  
Chonghui Yan ◽  
...  

2000 ◽  
Vol 47 (1-2) ◽  
pp. 114-126
Author(s):  
Sylvia Kirchengast ◽  
Beda Hartmann

2021 ◽  
Vol 2 (2) ◽  
pp. 3486-3509
Author(s):  
José Franco–Monsreal ◽  
Lidia Esther del Socorro Serralta–Peraza ◽  
Javier Jesús Flores–Abuxapqui

Low birth weight is an indicator that allows predicting the probability of survival of a child. In fact, there is an exponential relationship between weight deficit, gestational age, and perinatal mortality. In addition, it is important to indicate that a percentage of term children (37 ≤ weeks of gestation ≤ 41) who have low birth weight present with various sequelae of variable severity –especially in the neurological sphere– and hence the importance of predicting the presentation of low birth weight. Multiple Logistic Regression is one of the most expressive and versatile statistical instruments available for data analysis in both clinical and epidemiology. Its origin dates to the sixties with the transcendent work of Cornfield, Gordon & Smith on the risk of suffering from coronary heart disease and, in the way we know it today, with the contribution of Walter & Duncan in which addresses the issue of estimating the probability of occurrence of a certain event based on several variables. Its use has been universalized and expanded since the early eighties, due to the computer facilities available since then. Quantitative approach. The study design corresponds to that of an analytical observational epidemiological study of cases and controls with directionality response variable→explanatory variables and with prospective temporality. One thousand eight hundred fifteen newborns were studied [178 (9.81%) cases and 1,637 (90.19%) controls], which corresponds to nine controls per case. All term newborns (37 ≤ weeks of gestation ≤ 41) with weights < 2,500 g and ≥ 2,500 g were defined, respectively, as a case and as a control. The values obtained from the β Exponents or Odds Ratios indicate the positive contribution (OR> 1) in ascending numerical order of the explanatory variables alcoholism (0.0018); low socioeconomic level (0.5694); initiation of prenatal care from or after the 20th week of gestation (0.6116); birth interval ≤ 24 months (0.7942); age at menarche ≤ 12 years (1.0792); “unmarried” marital status (1.0961); female gender of the product (1.1271); maternal weight < 50 kg (1.4700); history of abortion(s) (1.5407); number of deliveries = 1 (1.5524); number of prenatal visits ≤ 5 (1.5966); type of delivery or abdominal birth route (1.6169); smoking (2.2019); number of deliveries ≥ 5 (2.2714); maternal age ≤ 19 years (2.4827); maternal age ≥ 36 years (2.8070); pathological obstetric history (4.0735); pathological personal history (4.6475); and maternal height < 150 cm (5.5092).


2018 ◽  
Vol 9 (6) ◽  
pp. 3432-3446 ◽  
Author(s):  
Melinda Csongová ◽  
Radana Gurecká ◽  
Ivana Koborová ◽  
Peter Celec ◽  
Emese Domonkos ◽  
...  

A maternal AGE-rich diet during pregnancy affects the early neuromotor development of offspring consuming a standard diet, and the metabolic status of male progeny.


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