The association between thyroid function and incidence of metabolic syndrome in euthyroid subjects: Tianjin chronic low-grade systemic inflammation and health cohort study

2018 ◽  
Vol 88 (5) ◽  
pp. 735-743 ◽  
Author(s):  
Yeqing Gu ◽  
Yanyan Wang ◽  
Qing Zhang ◽  
Li Liu ◽  
Ge Meng ◽  
...  
2017 ◽  
Author(s):  
Bruce Wolffenbuttel ◽  
Hanneke Wouters ◽  
Sandra Slagter ◽  
Waateringe Robert van ◽  
Vliet-Ostaptchouk Jana van ◽  
...  

2019 ◽  
Author(s):  
Hongmei Wu ◽  
Mingyue Liu ◽  
Qing Zhang ◽  
Li Liu ◽  
Ge Meng ◽  
...  

Abstract Background although handgrip strength (HGS) is considered an excellent predictor of morbidity and mortality, there are few reference data available, especially across life from young to old populations. Objective to investigate the reference values and determinants for HGS in a large Chinese adult population. Design this cross-sectional study used data from the Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study ranging from 2013 to 2017. Setting and subjects in total, 37,707 Chinese adults aged 18–93 years with measures of HGS were included. Methods HGS was measured using a handheld digital dynamometer. The percentile distribution of HGS, as well as mean (standard deviation) values of HGS, was calculated according to sex and age categories. The Pearson’s or Spearman’s correlation coefficient and multiple linear regression were also used. Results the peak mean value of HGS was 45.2 ± 6.88 kg in men and 26.8 ± 4.65 kg in women. Different reference values for each sex and age category are present. The prevalence of low HGS was 7.69% in men and 6.46% in women. Multiple regression analysis showed that almost 72.5% of HGS variability can be explained by sex, age, height and weight. Conclusions the HGS reached peak at 40 years old, maintained or slightly lowered between ages 40 and50 and then start an accelerated decline after 50 years old. Reference values of HGS should be stratified by sex and age group. HGS variability can be largely explained by sex, age, height and weight.


2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Shaomei Sun ◽  
Hongmei Wu ◽  
Qing Zhang ◽  
Chongjin Wang ◽  
Yinting Guo ◽  
...  

Few studies have assessed the relationship between a subnormal inflammatory status and metabolic syndrome (MS). We therefore designed a cross-sectional and 5-year cohort study to evaluate how a subnormal peripheral blood leukocyte count is related to MS. Participants were recruited from Tianjin Medical University General Hospital-Health Management Centre. Both a baseline cross-sectional (n=46,179) and a prospective assessment (n=13,061) were performed. Participants without a history of MS were followed up for 5 years. Leukocyte counts and MS components were assessed at baseline and yearly during the follow-up. Adjusted logistic and Cox proportional hazards regression models were used to assess relationships between the categories of leukocyte counts and MS. The subnormal leukocyte counts group (1,100–3,900 cells/mm3) had the lowest prevalence and incidence of MS. The odds ratio and hazard ratio (95% confidence interval) of the highest leukocyte counts were 1.98 (1.57–2.49) and 1.50 (1.22–1.84) (bothPfor trend <0.0001), respectively, when compared to the subnormal leukocyte counts group after adjusting for potential confounders. This study has shown that subnormal leukocyte counts are independently related to the lowest prevalence and incidence of MS. The findings suggest that it is necessary to restudy and discuss the clinical or preventive value of subnormal leukocyte counts.


Aging ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 7350-7360
Author(s):  
Meng Ren ◽  
Lili You ◽  
Diaozhu Lin ◽  
Qiling Feng ◽  
Chulin Huang ◽  
...  

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