scholarly journals In vitro survival of scabies mites

2020 ◽  
Vol 45 (6) ◽  
pp. 712-715 ◽  
Author(s):  
K. Pallesen ◽  
J. A. Lassen ◽  
N. T. Munk ◽  
G. N. Hartmeyer ◽  
L. Hvid ◽  
...  
Keyword(s):  
In Vitro Survival

scholarly journals Imaging prior to radiotherapy impacts in-vitro survival

2020 ◽  
Vol 16 ◽  
pp. 138-143
Author(s):  
Peter L. Kench ◽  
Linda Rogers ◽  
Ana Esteves ◽  
Tina Gorjiara ◽  
Elizabeth Claridge Mackonis ◽  
...  
Keyword(s):  
In Vitro Survival

scholarly journals A novel in vitro survival assay of small intestinal stem cells after exposure to ionizing radiation

2014 ◽  
Vol 55 (2) ◽  
pp. 381-390 ◽  
Author(s):  
Motohiro Yamauchi ◽  
Kensuke Otsuka ◽  
Hisayoshi Kondo ◽  
Nobuyuki Hamada ◽  
Masanori Tomita ◽  
...  
Keyword(s):  
Stem Cells ◽  
Ionizing Radiation ◽  
Intestinal Stem Cells ◽  
Survival Assay ◽  
Small Intestinal ◽  
In Vitro Survival

scholarly journals Imaging dose affects in vitro survival following subsequent therapeutic irradiation

2015 ◽  
Vol 1 (4) ◽  
pp. 045016
Author(s):  
Linda J Rogers ◽  
Natalka Suchowerska ◽  
Anna Ralston ◽  
Anna Napper ◽  
David R McKenzie
Keyword(s):  
Imaging Dose ◽  
Therapeutic Irradiation ◽  
In Vitro Survival

scholarly journals Effect of Cryoprotectant Gradient Equilibration Method on In Vitro Survival Rate and Pregnancy Rate of Bovine IVF Blastocysts.

2001 ◽  
Vol 18 (2) ◽  
pp. 67-71
Author(s):  
Yutaka Kajihara ◽  
Atsurou Hira ◽  
Ryouhei Nitta ◽  
Yoshihiko Nakanishi
Keyword(s):  
Survival Rate ◽  
Pregnancy Rate ◽  
In Vitro Survival

In vitro survival of Listeria monocytogenes in human amniotic fluid

1999 ◽  
Vol 202 (5) ◽  
pp. 377-382 ◽  
Author(s):  
Clelia Altieri ◽  
Giuseppe Maruotti ◽  
Costanzo Natale ◽  
Salvatore Massa
Keyword(s):  
Listeria Monocytogenes ◽  
Amniotic Fluid ◽  
Human Amniotic Fluid ◽  
In Vitro Survival

Efficacy of dihydroartemisinin/piperaquine in patients with non-complicated Plasmodium falciparum malaria in Yaoundé, Cameroon

2021 ◽  
Author(s):  
Mélissa Mairet-Khedim ◽  
Sandrine Nsango ◽  
Christelle Ngou ◽  
Sandie Menard ◽  
Camille Roesch ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Southeast Asia ◽  
Falciparum Malaria ◽  
Gene Polymorphisms ◽  
Plasmodium Falciparum Malaria ◽  
Molecular Profile ◽  
Uncomplicated Plasmodium Falciparum Malaria ◽  
In Vitro Survival ◽  
Phenotypic Susceptibility

Abstract Background Dihydroartemisinin/piperaquine is increasingly used for the treatment of uncomplicated Plasmodium falciparum malaria in Africa. The efficacy of this combination in Cameroon is poorly documented, while resistance to dihydroartemisinin/piperaquine readily spreads in Southeast Asia. Objectives This study evaluated the clinical efficacy of dihydroartemisinin/piperaquine in Cameroon, as well as the molecular profile and phenotypic susceptibility of collected isolates to dihydroartemisinin and piperaquine. Patients and methods Dihydroartemisinin/piperaquine efficacy in 42 days was followed-up for 138 patients presenting non-complicated falciparum malaria. Piperaquine concentration was determined at day 7 for 124 patients. kelch13 gene polymorphisms (n = 150) and plasmepsin2 gene amplification (n = 148) were determined as molecular markers of resistance to dihydroartemisinin and piperaquine, respectively. Parasite susceptibility to dihydroartemisinin and piperaquine was determined using validated in vitro survival assays. Results The efficacy of dihydroartemisinin/piperaquine treatment was 100% after PCR correction. The reinfections were not associated with a variation of piperaquine concentration at day 7. Ninety-six percent (144/150) of the samples presented a WT allele of the kelch13 gene. Two percent (3/150) presented the non-synonymous mutation A578S, which is not associated with resistance to dihydroartemisinin. No duplication of the plasmepsin2 gene was observed (0/148). All the samples tested in vitro by survival assays (n = 87) were susceptible to dihydroartemisinin and piperaquine. Conclusions Dihydroartemisinin/piperaquine has demonstrated excellent therapeutic efficacy with no evidence of emerging artemisinin or piperaquine resistance in Yaoundé, Cameroon. This observation suggests that dihydroartemisinin/piperaquine could be a sustainable therapeutic solution for P. falciparum malaria if implemented in areas previously free of artemisinin- and piperaquine-resistant parasites, unlike Southeast Asia.

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