scholarly journals Micronutritional supplementation with a holoBLG based FSMP (food for specific medical purposes)‐lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect

2021 ◽  
Author(s):  
Sheriene Moussa Afify ◽  
Andreas Regner ◽  
Luis F. Pacios ◽  
Bart R. Blokhuis ◽  
Sebastian A. Jensen ◽  
...  
Keyword(s):  
Allergic Symptoms

scholarly journals Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 738
Author(s):  
Nazanin Samadi ◽  
Denise Heiden ◽  
Martina Klems ◽  
Martina Salzmann ◽  
Johanna Rohrhofer ◽  
...  
Keyword(s):  
Food Allergy ◽  
Mouse Model ◽  
Gastric Acid ◽  
Clinical Symptoms ◽  
Acid Suppression ◽  
Gastric Digestion ◽  
Enzyme Solution ◽  
Allergic Symptoms ◽  
Gastric Acid Suppression ◽  
The Impact

Impaired gastric digestion due to suppressed gastric acidity enhances the risk for food allergy development. In the current study, we aimed to evaluate the impact of a supported gastric digestion via application of a pharmaceutical gastric enzyme solution (GES) on food allergy development and allergic reactions in a BALB/c mouse model. The ability of the GES to restore hypoacidic conditions was tested in mice treated with gastric acid suppression medication. To evaluate the impact on allergic symptoms, mice were orally sensitized with ovalbumin (OVA) under gastric acid suppression and subjected to oral challenges with or without GES. The immune response was evaluated by measurement of antibody titers, cytokine levels, mucosal allergy effector cell influx and regulatory T-cell counts. Clinical response was objectified by core body temperature measurements after oral OVA challenge. Supplementation of GES transiently restored physiological pH levels in the stomach after pharmaceutical gastric acid suppression. During oral sensitization, supplementation of gastric enzymes significantly reduced systemic IgE, IgG1 and IgG2a levels and allergic symptoms. In food allergic mice, clinical symptoms were reduced by co-administration of the gastric enzyme solution. Support of gastric digestion efficiently prevents food allergy induction and alleviates clinical symptoms in our food allergy model.

Association between ventilation rates in 390 Swedish homes and allergic symptoms in children

Indoor Air ◽  
2005 ◽  
Vol 15 (4) ◽  
pp. 275-280 ◽  
Author(s):  
C. G. Bornehag ◽  
J. Sundell ◽  
L. Hagerhed-Engman ◽  
T. Sigsgaard
Keyword(s):  
Allergic Symptoms ◽  
Ventilation Rates

scholarly journals Prevalence of allergic symptoms in young adults after wheezing during preschool

2020 ◽  
Vol 13 (8) ◽  
pp. 100210
Author(s):  
Bashir Omarjee ◽  
Serge Kah ◽  
Bernard Gregoire-Krikorian ◽  
Patrick Gros
Keyword(s):  
Young Adults ◽  
Allergic Symptoms

scholarly journals Coexistence of asthmatic and non-respiratory allergic symptoms in children of Batumi Region, Georgia: occurrence and association with known diagnosis of asthma

2021 ◽  
Vol 29 (1) ◽  
pp. 23-27
Author(s):  
Vakhtang Beridze ◽  
Tamar Bakhtadze ◽  
Sophio Beridze ◽  
Karaman Phagava ◽  
Ivane Chkhaidze ◽  
...  
Keyword(s):  
Allergic Symptoms
Sign in / Sign up

Export Citation Format

Share Document