scholarly journals Maternal and neonatal 25‐hydroxyvitamin D concentrations and school‐age lung function, asthma and allergy. The Generation R Study

2019 ◽  
Vol 49 (6) ◽  
pp. 900-910 ◽  
Author(s):  
Sara M. Mensink‐Bout ◽  
Evelien R. Meel ◽  
Johan C. Jongste ◽  
Trudy Voortman ◽  
Irwin K. Reiss ◽  
...  
2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A173.2-A173
Author(s):  
J Huang ◽  
TC Yao ◽  
W Yeh ◽  
S Lai ◽  
S Liao ◽  
...  

2020 ◽  
Vol 9 (10) ◽  
pp. 3345
Author(s):  
Manuel Sanchez-Solis ◽  
Maria Soledad Parra-Carrillo ◽  
Pedro Mondejar-Lopez ◽  
Patricia W Garcia-Marcos ◽  
Luis Garcia-Marcos

Background: The aim of the study is to assess whether lung function of infants born preterm predicts wheezing in pre-school age. Methods: A survey of the core wheezing questionnaire of the International Study on Asthma and Allergy in Children was administered to parents of preterm newborns, to whom lung function tests were performed at a corrected age of six months, and who, at the time of the survey, were between three and nine years of age. Results: Low values of all lung function parameters measured, except FVC, were predictors of wheezing at some time in life, (FEV0.5 OR: 0.62 (95%CI 0.39; 0.995); FEV0.5/FVC OR: 0.73 (0.54; 0.99)) FEF75 OR: 0.60 [0.37; 0.93]; FEF25-75 OR: 0.57 (0.37; 0.89)); and of wheezing in the past year (FEV0.5 OR: 0.36 (0.17; 0.76); FEV0.5/FVC OR: 0.59 (0.38; 0.93); FEF75 OR: 0.38 [0.19; 0.76]; FEF25-75 OR: 0.35 (0.17; 0.70). In addition, FEV0.5/FVC values lower than the lowest limit of normality, were predictive of hospital admissions due to wheezing (OR: 3.07; (1.02; 9.25)). Conclusions: Limited lung function in infancy is predictive of both future wheezing and hospitalization for a wheezing episode.


2014 ◽  
Vol 45 (4) ◽  
pp. 1019-1026 ◽  
Author(s):  
Tricia L. Larose ◽  
Arnulf Langhammer ◽  
Yue Chen ◽  
Carlos A. Camargo ◽  
Pål Romundstad ◽  
...  

The association between vitamin D status and lung function in adults with asthma remains unclear.We studied this cross-sectional association and possible modification by sex and allergic rhinitis in 760 adults (aged 19–55 years) with self-reported asthma in the Nord-Trøndelag Health Study. Serum 25-hydroxyvitamin D (25(OH)D) level <50 nmol·L−1was considered deficient. Lung function measurements included forced expiratory volume in 1 s (FEV1) % predicted, forced vital capacity (FVC) % predicted and FEV1/FVC ratio. Multiple linear regression models were used to estimate adjusted regression coefficients (β) and 95% confidence intervals.44% of asthma adults had serum 25(OH)D levels <50 nmol·L−1. Its associations with lung function measures seemed to be modified by sex and allergic rhinitis (p<0.03 for three-way interaction term). Overall, a serum 25(OH)D level <50 nmol·L−1was not associated with lung function measurements in subjects with allergic rhinitis in this asthma cohort. In men with asthma but without allergic rhinitis, however, a serum 25(OH)D level <50 nmol·L−1was significantly associated with lower FEV1/FVC ratio (β=−8.60%; 95% CI: −16.95%– −0.25%).Low serum 25(OH)D level was not associated with airway obstruction in most asthma adults with the exception of men with asthma but without allergic rhinitis.


Thorax ◽  
2013 ◽  
Vol 69 (1) ◽  
pp. 24-31 ◽  
Author(s):  
Shoaib Afzal ◽  
Peter Lange ◽  
Stig E Bojesen ◽  
Jacob J Freiberg ◽  
Børge G Nordestgaard

2020 ◽  
Vol 40 ◽  
pp. 537-538
Author(s):  
A.J. Causer ◽  
Z.L. Saynor ◽  
I. Arregui-Fresneda ◽  
G. Connett ◽  
M.I. Allenby ◽  
...  

2013 ◽  
Vol 43 (10) ◽  
pp. 1180-1188 ◽  
Author(s):  
A. K. Wills ◽  
S. O. Shaheen ◽  
R. Granell ◽  
A. J. Henderson ◽  
W. D. Fraser ◽  
...  

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