Characterization of sensitization to furry animal allergen components in an adult population

2019 ◽  
Vol 49 (4) ◽  
pp. 495-505 ◽  
Author(s):  
Shintaro Suzuki ◽  
Bright I. Nwaru ◽  
Linda Ekerljung ◽  
Sigrid Sjölander ◽  
Roxana Mincheva ◽  
...  
Keyword(s):  
Adult Population ◽  
Allergen Components ◽  
Animal Allergen

scholarly journals Epidemiological and Molecular Characterization of an Invasive Group A Streptococcusemm32.2 Outbreak

2017 ◽  
Vol 55 (6) ◽  
pp. 1837-1846 ◽  
Author(s):  
Jennifer E. Cornick ◽  
Anmol M. Kiran ◽  
Roberto Vivancos ◽  
Jon Van Aartsen ◽  
Jenny Clarke ◽  
...  
Keyword(s):  
Group A Streptococcus ◽  
Adult Population ◽  
Sequencing Analysis ◽  
Invasive Group ◽  
Disadvantaged Population ◽  
Specific Subset ◽  
Time Period ◽  
Case Comparison ◽  
Group A

ABSTRACTAnemm32.2 invasive group A streptococcus (iGAS) outbreak occurred in Liverpool from January 2010 to September 2012. This genotype had not previously been identified in Liverpool, but was responsible for 32% (14/44) of all iGAS cases reported during this time period. We performed a case-case comparison ofemm32.2 iGAS cases with non-emm32.2 control iGAS cases identified in the Liverpool population over the same time period to assess patient risk factors foremm32.2 iGAS infection. Theemm32.2 iGAS cases were confined to the adult population. We show that homelessness, intravenous drug use, and alcohol abuse predisposed patients toemm32.2 iGAS disease; however, no obvious epidemiological linkage between the patients withemm32.2 iGAS could be identified. Comparative whole-genome sequencing analysis ofemm32.2 iGAS and non-emm32.2 control isolates was also performed to identify pathogen factors which might have driven the outbreak. We identified 19 genes, five of which had previously been implicated in virulence, which were present in all of theemm32.2 iGAS isolates but not present in any of the non-emm32.2 control isolates. We report that a novelemm32.2 genotype emerged in Liverpool in 2010 and identified a specific subset of genes, which could have allowed this novelemm32.2 genotype to persist in a disadvantaged population in the region over a 3-year period.

IgE to Furry Animal Allergen Components Was Associated with Asthma in a Population-Based Study of Adults

2015 ◽  
Vol 135 (2) ◽  
pp. AB22
Author(s):  
Sigrid Sjolander ◽  
Anders Bjerg ◽  
Linda Ekerljung ◽  
Otti Bengtsson-Gref ◽  
Magnus Borres ◽  
...  
Keyword(s):  
Population Based ◽  
Population Based Study ◽  
Allergen Components ◽  
Animal Allergen

scholarly journals Detection and molecular characterization of respiratory viruses that cause acute respiratory infection in the adult population

2019 ◽  
Vol 155 (91) ◽  
Author(s):  
Dylan Lucía Díaz-Chiguer ◽  
Rocío Tirado-Mendoza ◽  
Adrián Márquez-Navarro ◽  
Javier Rolando Ambrosio-Hernández ◽  
Ismael Ruiz-Fraga ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Adult Population ◽  
Respiratory Viruses

scholarly journals Endocannabinoid system

2020 ◽  
Vol 8 (9) ◽  
pp. 354-358
Author(s):  
Luis Henrique Almeida Castro ◽  
Geanlucas Mendes Monteiro ◽  
Ygor Thiago Cerqueira de Paula ◽  
Vanessa De Souza Ferraz ◽  
Flavia Soares Bezerra Okumoto Nery de Mello ◽  
...  
Keyword(s):  
Cannabis Sativa ◽  
Adult Population ◽  
Chemical Characterization ◽  
Endocannabinoid System ◽  
Neuronal Homeostasis ◽  
Medicinal Use ◽  
Main Component ◽  
Recreational Use ◽  
Small Chemical

Among the drugs considered illicit in the West, the Cannabis sativa plant is the most consumed: around 4% of the adult population, 10% of these users are in a situation of dependence. However, the medicinal use of this herb dates back to the early days of the emergence of our own species: some anthropologists theorize that some of the genus Homo has progressed in the struggle for survival with other hominids precisely because of the advanced knowledge – kept to the proper proportions – it possessed of plants like Cannabis. Millennia later, science – even focusing intensely on the chemical characterization of its more than 530 bioactive components – was still not able to generate verifiable hypotheses in order to explain two of the most remarkable characteristics of the recreational use of this plant: because small chemical changes potentiated the effect of the drug up to 100 times and, mainly, because it would be virtually impossible for an individual to suffer a lethal overdose of the substance. To overcome this paradigm, some compounds derived from delta-ninetetrahydrocannabinol (Δ9-THC) - the main component of cannabis – were radioactively marked in an experimental study and, after their induction, it was discovered that they had tropism by brain membranes and that their binding was saturated and stereosleptic. Such evidence strongly suggested the existence of endogenous receptors for the drug and it was these findings that led to the discovery of the Endocanabinoid System (SEC): a physiological apparatus made up of endogenous receptors and binders, philogenetically conserved, responsible for several controls related to neuronal homeostasis.

scholarly journals Marginal zone lymphomas in children and the young adult population; characterization of genetic aberrations by FISH and RT-PCR

2010 ◽  
Vol 23 (6) ◽  
pp. 866-873 ◽  
Author(s):  
Kathryn A Rizzo ◽  
Berthold Streubel ◽  
Stefania Pittaluga ◽  
Andreas Chott ◽  
Liqiang Xi ◽  
...  
Keyword(s):  
Young Adult ◽  
Marginal Zone ◽  
Adult Population ◽  
Rt Pcr ◽  
Genetic Aberrations ◽  
Young Adult Population
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