A Fluorescent Probe for Imaging p53-MDM2 Protein-Protein Interaction

2014 ◽  
Vol 85 (4) ◽  
pp. 411-417 ◽  
Author(s):  
Zhenzhen Liu ◽  
Zhenyuan Miao ◽  
Jin Li ◽  
Kun Fang ◽  
Chunlin Zhuang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Protein Interaction ◽  
Mdm2 Protein ◽  
Protein Protein Interaction

Synthesis and cytotoxicity of novel dispiro derivatives of 5-arylidenoxazolones, potential inhibitors of p53—MDM2 protein-protein interaction

2018 ◽  
Vol 67 (3) ◽  
pp. 562-569 ◽  
Author(s):  
A. А. Beloglazkina ◽  
D. А. Skvortsov ◽  
V. A. Tafeenko ◽  
А. G. Majouga ◽  
N. V. Zyk ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Mdm2 Protein ◽  
Protein Protein Interaction ◽  
Potential Inhibitors ◽  
Derivatives Of

scholarly journals Recent Small-Molecule Inhibitors of the p53–MDM2 Protein–Protein Interaction

Molecules ◽  
2020 ◽  
Vol 25 (5) ◽  
pp. 1211 ◽  
Author(s):  
Anastasia Beloglazkina ◽  
Nikolai Zyk ◽  
Alexander Majouga ◽  
Elena Beloglazkina
Keyword(s):  
Small Molecule ◽  
Protein Interaction ◽  
Small Molecule Inhibitors ◽  
Mdm2 Protein ◽  
Binding Characteristics ◽  
Protein Protein Interaction ◽  
Mouse Double Minute ◽  
Double Minute ◽  
Synthetic Approaches

This review presents the last decade of studies on the synthesis of various types of small-molecule inhibitors of the p53– Mouse double minute 2 homolog (MDM2) protein–protein interaction. The main focus is placed on synthetic approaches to such molecules, their cytotoxicity, and MDM2 binding characteristics.

scholarly journals Correction: Environment-sensitive turn-on fluorescent probes for p53–MDM2 protein–protein interaction

MedChemComm ◽  
2017 ◽  
Vol 8 (8) ◽  
pp. 1727-1727 ◽  
Author(s):  
Tingting Liu ◽  
Yan Jiang ◽  
Zhenzhen Liu ◽  
Jin Li ◽  
Kun Fang ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Fluorescent Probes ◽  
Mdm2 Protein ◽  
Protein Protein Interaction ◽  
Turn On

Correction for ‘Environment-sensitive turn-on fluorescent probes for p53–MDM2 protein–protein interaction’ by Tingting Liu et al., MedChemCommun, 2017, DOI: 10.1039/c7md00287d.

‘Light up’ protein–protein interaction through bioorthogonal incorporation of a turn-on fluorescent probe into β-lactamase

2016 ◽  
Vol 12 (12) ◽  
pp. 3544-3549 ◽  
Author(s):  
Rui Hu ◽  
Hong-Kin Yap ◽  
Yik-Hong Fung ◽  
Yong Wang ◽  
Wing-Lam Cheong ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Protein Interaction ◽  
Protein Protein Interaction ◽  
Turn On

Aggregation induced emissive compound EPB can detect protein–protein interaction.

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