scholarly journals Management strategies in Lynch syndrome and familial adenomatous polyposis: a national healthcare survey in Japan

2017 ◽  
Vol 108 (2) ◽  
pp. 243-249 ◽  
Author(s):  
Tomoki Yamano ◽  
Michiko Hamanaka ◽  
Akihito Babaya ◽  
Kei Kimura ◽  
Masayoshi Kobayashi ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Lynch Syndrome ◽  
Management Strategies ◽  
Adenomatous Polyposis ◽  
National Healthcare ◽  
Healthcare Survey

Hereditary Colorectal Cancer and Polyposis Syndromes

2021 ◽  
Author(s):  
Jose G. Guillem ◽  
John B Ammori
Keyword(s):  
Colorectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Lynch Syndrome ◽  
Juvenile Polyposis ◽  
Prophylactic Surgery ◽  
Cancer Type ◽  
Adenomatous Polyposis ◽  
Juvenile Polyposis Syndrome ◽  
Polyposis Syndrome ◽  
Peutz Jeghers Syndrome

The majority of cases of inherited colorectal cancer (CRC) are accounted for by two syndromes: Lynch syndrome and familial adenomatous polyposis (FAP). In the management of FAP, the role of prophylactic surgery is clearly defined, although the optimal procedure for an individual patient depends on a number of factors. In the management of Lynch syndrome, the indications for prophylactic procedures are emerging. The authors address the clinical evaluation, investigation findings, medical and surgical therapy, and extracolonic diseases of FAP, attenuated form of FAP (AFAP), MYH-associated polyposis, Lynch syndrome, familial colorectal cancer type X (FCCTX), hyperplastic polyposis syndrome, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. AFAP has been described that is associated with fewer adenomas and later development of CRC compared with classic FAP. The AFAP phenotype occurs in less than 10% of FAP patients. The clinical criteria for AFAP are no family members with more than 100 adenomas before the age of 30 years and (1) at least two patients with 10 to 99 adenomas at age over 30 years or (2) one patient with 10 to 99 adenomas at age over 30 years and a first-degree relative with CRC with few adenomas. Given that polyposis has a later onset and the risk of CRC is less well established in AFAP, some authors question whether prophylactic colectomy is necessary in all AFAP patients. This review contains 26 tables and 173 references Keywords: Colorectal cancer, Lynch syndrome, hyperplastic polyp, Peutz-Jeghers syndrome, juvenile polyposis syndrome, familial adenomatous polyposis

2021 Systematic genetic analysis of familial adenomatous polyposis and lynch syndrome

2015 ◽  
Vol 51 ◽  
pp. S335
Author(s):  
F. Taniguchi ◽  
T. Nagasaka ◽  
Y. Takehara ◽  
Y. Umeda ◽  
Y. Mori ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Genetic Analysis ◽  
Lynch Syndrome ◽  
Adenomatous Polyposis

scholarly journals Translational Research in Familial Colorectal Cancer Syndromes

2018 ◽  
Vol 31 (03) ◽  
pp. 161-167
Author(s):  
Molly Ford
Keyword(s):  
Colorectal Cancer ◽  
Genetic Testing ◽  
Familial Adenomatous Polyposis ◽  
Lynch Syndrome ◽  
Adenomatous Polyposis ◽  
Familial Colorectal Cancer ◽  
Inherited Cancer ◽  
Cancer Syndromes ◽  
Early Onset Colorectal Cancer ◽  
Made In

AbstractGrowing knowledge of inherited colorectal cancer syndromes has led to better surveillance and better care of this subset of patients. The most well-known entities, including Lynch syndrome and familial adenomatous polyposis, are continually being studied and with the advent of more sophisticated genetic testing, additional genetic discoveries have been made in the field of inherited cancer. This article will summarize many of the updates to both the familiar and perhaps less familiar syndromes that can lead to inherited or early-onset colorectal cancer.

scholarly journals Benign Fibroepithelial Polyp of Renal Pelvis in a Patient with Familial Adenomatous Polyposis: A Successful Percutaneous Nephroscopic Management Strategy

2009 ◽  
Vol 2009 ◽  
pp. 1-3
Author(s):  
Nikhil Vasdev ◽  
Philippa Holmes ◽  
Katie Senior ◽  
Philip Haslam ◽  
Tahseen Hasan ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Renal Pelvis ◽  
Management Strategy ◽  
Rare Case ◽  
Management Strategies ◽  
Invasive Technique ◽  
Adenomatous Polyposis ◽  
Fibroepithelial Polyp ◽  
Current Review ◽  
A Current

We present a rare case of a benign fibroepithelial polyp of the renal pelvis in a patient with familial adenomatous polyposis. In our paper we describe a new minimally invasive technique developed in our unit using an amplatz goose neck snare via a percutaneous nephroscope sheath in the management of the benign fibroepithelial polyp of the renal pelvis and present a current review of management strategies in literature.

scholarly journals Molecular and Pathological Features of Gastric Cancer in Lynch Syndrome and Familial Adenomatous Polyposis

2018 ◽  
Vol 19 (6) ◽  
pp. 1682 ◽  
Author(s):  
Mara Fornasarig ◽  
Raffaella Magris ◽  
Valli De Re ◽  
Ettore Bidoli ◽  
Vincenzo Canzonieri ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Familial Adenomatous Polyposis ◽  
Lynch Syndrome ◽  
Adenomatous Polyposis ◽  
Pathological Features
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