scholarly journals The role of the skin microbiome in atopic dermatitis: a systematic review

2017 ◽  
Vol 177 (5) ◽  
pp. 1272-1278 ◽  
Author(s):  
R.D. Bjerre ◽  
J. Bandier ◽  
L. Skov ◽  
L. Engstrand ◽  
J.D. Johansen
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Skin Microbiome

scholarly journals The role of the skin microbiome in atopic dermatitis

2019 ◽  
Vol 122 (3) ◽  
pp. 263-269 ◽  
Author(s):  
Teruaki Nakatsuji ◽  
Richard L. Gallo
Keyword(s):  
Atopic Dermatitis ◽  
Skin Microbiome

Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: A systematic review and meta-analysis

2015 ◽  
Vol 72 (6) ◽  
pp. 992-1002 ◽  
Author(s):  
Laureline Legendre ◽  
Thomas Barnetche ◽  
Juliette Mazereeuw-Hautier ◽  
Nicolas Meyer ◽  
Dedee Murrell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Topical Treatment ◽  
Meta Analysis

Skin microbiomein adult atopic dermatitis

2018 ◽  
pp. 209-214
Author(s):  
О.В. Кандалова ◽  
И.В. Елистратова ◽  
О.Б. Иванченко ◽  
А.В. Гречко ◽  
С.Г. Морозов
Keyword(s):  
Atopic Dermatitis ◽  
Environmental Factors ◽  
Bacterial Infection ◽  
Adaptive Immunity ◽  
Bacterial Contamination ◽  
Proteolytic Enzymes ◽  
Regulatory Proteins ◽  
Skin Microbiome ◽  
Innate And Adaptive Immunity

Данный миниобзор посвящен изучению роли микробиома кожи и, в частности, роли стафилококков в обострении атопического дерматита у взрослых людей. Были проанализированы предпосылки бактериальной контаминации кожи и роль факторов внешней среды. Представлены данные по влиянию S. aureaus на разные звенья природного и адаптивного иммунитета за счет синтеза специфических регуляторных белков, протеолитических ферментов и гидролаз. Обозначены некоторые направления борьбы с бактериальной инфекцией для предупреждения обострения атопического дерматита у взрослых. In this mini review we have analyzed the role of skin microbiome in the atopic dermatitis relapse in adults, in particular, a role of S. aureaus in this process. The background for the skin bacterial contamination under the influence of environmental factors has been analyzed. We reviewed some S. aureaus effects on the components of innate and adaptive immunity due to the secretion of specific regulatory proteins, a number of proteolytic enzymes, and some hydrolases. There were indicated some ways to eliminate the bacterial infection to prevent the atopic dermatitis relapse in adults

The role of skin microbiome in atopic dermatitis

2017 ◽  
Vol 93 (5) ◽  
pp. 202-208
Author(s):  
László Hunor Gergely ◽  
◽  
Miklós Sárdy ◽  
Noémi Muhalik
Keyword(s):  
Atopic Dermatitis ◽  
Skin Microbiome

The emerging role of skin microbiome in atopic dermatitis and its clinical implication

2018 ◽  
Vol 30 (4) ◽  
pp. 357-364 ◽  
Author(s):  
Jean-François Stalder ◽  
Joachim W. Fluhr ◽  
Tim Foster ◽  
Martin Glatz ◽  
Ehrhardt Proksch
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Implication ◽  
Skin Microbiome

scholarly journals Changes in Skin and Nasal Microbiome and Staphylococcal Species Following Treatment of Atopic Dermatitis with Dupilumab

2021 ◽  
Vol 9 (7) ◽  
pp. 1487
Author(s):  
Caroline Meyer Olesen ◽  
Anna Cäcilia Ingham ◽  
Simon Francis Thomsen ◽  
Maja-Lisa Clausen ◽  
Paal Skytt Andersen ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Clinical Improvement ◽  
Bacterial Community Structure ◽  
Gene Sequencing ◽  
Skin Microbiome ◽  
Sequencing Data ◽  
Tuf Gene ◽  
Targeted Treatments ◽  
Before And After

Investigation of changes in the skin microbiome following treatment of atopic dermatitis (AD) with dupilumab may provide valuable insights into the skin microbiome as a therapeutic target. The aim of this study is to assess changes in the AD skin microbiome following treatment of AD with dupilumab (n = 27). E-swabs were collected from nose, lesional, and nonlesional skin before and after 16 weeks of dupilumab therapy, and the microbiome was analyzed by 16S rRNA and tuf gene sequencing. Data for 17 patients with milder disease receiving treatment with non-targeted therapies are also presented. The results show that both groups experienced clinical improvement (p < 0.001) following dupilumab therapy and that Shannon diversity increased and bacterial community structure changed. The relative abundance of the genus Staphylococcus (S.) and S. aureus decreased, while that of S. epidermidis and S. hominis increased. No significant changes were observed for patients receiving non-targeted treatments. The increases in S. epidermidis and S. hominis and the decrease in S. aureus correlated with clinical improvement. Furthermore, changes in S. hominis and S. epidermidis correlated inversely with S. aureus. In conclusion, treatment with dupilumab significantly changed the skin microbiome and decreased S. aureus. Our results suggest a favorable role of commensal staphylococci in AD.

scholarly journals Role of the Gut Microbiota in Atopic Dermatitis: A Systematic Review

2018 ◽  
pp. 0 ◽  
Author(s):  
E Pedersen ◽  
L Skov ◽  
J Thyssen ◽  
P Jensen
Keyword(s):  
Systematic Review ◽  
Atopic Dermatitis ◽  
Gut Microbiota
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